4-nitro-salicylaldehyde acetylhydrazone | 143361-72-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 4-nitro-salicylaldehyde acetylhydrazone
• 英文别名: N-(acetyl)-N'-(5-NO2-salicylidene)hydrazine；H2ahsNO2；N-[(2-hydroxy-5-nitrophenyl)methylideneamino]acetamide
• CAS: 143361-72-2
• 化学式: C₉H₉N₃O₄
• 分子量: 223.188
• InChiKey: IFTTYDJKKZDCHM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  108
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  4-nitro-salicylaldehyde acetylhydrazone 以 甲醇 为溶剂， 生成
  参考文献：
  名称：

  Lukov; Kogan; Levchenkov, Russian Journal of Inorganic Chemistry, 1998, vol. 43, # 3, p. 359 - 364

  摘要：

  DOI：
• 作为产物：
  描述：

  乙酰肼 、 5-硝基水杨醛 以 乙醇 为溶剂， 生成 4-nitro-salicylaldehyde acetylhydrazone
  参考文献：
  名称：

  Synthesis of 3-hydroxyindanones via potassium salt of amino acid catalyzed regioselective intramolecular aldolization of ortho-diacylbenzenes

  摘要：

  First organocatalytic intramolecular aldolization of ortho-diacylbenzenes to construct highly functionalized 3-hydroxyindanones is described. In this transformation a high trans-selectivity is achieved by the use of metal salt of amino acid. This method allows an easy access to the strained spiro-cyclic 3-hydroxyindanones related to a number of natural product frameworks. Synthesis of a new class of indole skeleton substituted by 3-hydroxyindanones added an extra essence to this new protocol. (C) 2015 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2015.01.077

文献信息

• Ruthenium(III) complexes with N-(acetyl)-N′-(5-R-salicylidene)hydrazines: Syntheses, structures and properties
  作者：Raji Raveendran、Samudranil Pal

  DOI：10.1016/j.poly.2007.10.027

  日期：2008.2

  The reactions of 1 mol equiv. each of [Ru(PPh3)(3)Cl-2] and N-(acetyl)-N'-(5-R-salicylidene)hydrazines (H(2)ahsR, R = H, OCH3, Cl, Br and NO2) in alcoholic media afford simultaneously two types of complexes having the general formulae [Ru(HahsR)(PPh3)(2)Cl-2] and [Ru(ahsR)(PPh3)(2)Cl]. The complexes have been characterized by elemental analysis, magnetic, spectroscopic and electrochemical measurements. Molecular structures of [Ru(HahsH)(PPh3)(2)Cl-2] and [Ru(ahsH)(PPh3)(2)Cl] have been confirmed by X-ray crystallography. In both species, the PPh3 ligands are trans to each other. The bidentate HahsH(-) coordinates to the metal ion via the 0 atom of the deprotonated amide and the imine-N atom in [Ru(HahsH)(PPh3)(2)Cl-2]. In HahsH(-), the phenolic OH is involved in a strong intramolecular hydrogen bond with the uncoordinated amide N atom forming a seven-membered ring. In [Ru(ahsH)(PPh3)(2)Cl], the tridentate ahsH(2-) binds to the metal ion via the deprotonated amide 0, the imine N and the phenolate 0 atoms. In the electronic spectra, the green [Ru(HahsR)(PPh3)(2)Cl-2] and brown [Ru(ahsR)(PPh3)(2)Cl] complexes display several absorptions in the ranges 385-283 and 457-269 nm, respectively. Both complexes are low-spin and display rhombic EPR spectra in frozen solutions. Both types of complexes are redox active and display a quasi-reversible ruthenium(III) to ruthenium(II) reduction which is sensitive to the polar effect of the substituent on the chelating ligand. The reduction potentials are in the ranges -0.21 to -0.12 and -0.42 to -0.21 V (versus Ag/AgCl) for [Ru(HahsR)(PPh3)(2)Cl-2] and [Ru(ahsR)(PPh3)(2)Cl], respectively. (c) 2007 Elsevier Ltd. All rights reserved.
• Lukov; Levchenkov; Kogan, Russian Journal of Inorganic Chemistry, 1997, vol. 42, # 4, p. 532 - 535
  作者：Lukov、Levchenkov、Kogan

  DOI：——

  日期：——
• Lukov; Levchenkov; Kogan, Russian Journal of Coordination Chemistry, 1998, vol. 24, # 12, p. 887 - 890
  作者：Lukov、Levchenkov、Kogan

  DOI：——

  日期：——