diheptadecyl-amine | 16130-73-7

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: diheptadecyl-amine
• 英文别名: N-heptadecylheptadecan-1-amine
• CAS: 16130-73-7
• 化学式: C₃₄H₇₁N
• 分子量: 493.944
• InChiKey: RLARTHIKSMHWBL-UHFFFAOYSA-N

物化性质

• 熔点：
  71°C
• 沸点：
  507.19°C (estimate)
• 密度：
  0.9052 (estimate)

计算性质

• 辛醇/水分配系数(LogP)：
  16.4
• 重原子数：
  35
• 可旋转键数：
  32
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  正十七胺 、 diheptadecyl-amine 、 聚合甲醛 生成 N,N-二甲基十七烷-1-胺
  参考文献：
  名称：

  FERNANDEZ, P.;VALLS, M.;BAYONA, J. M.;ALBALGES, J., ENVIRON. SCI. AND TECHNOL., 25,(1991) N, C. 547-550

  摘要：

  DOI：
• 作为产物：
  描述：

  正十七胺 在 镍 作用下， 生成 diheptadecyl-amine
  参考文献：
  名称：

  Arbusow; Kataewa, Zhurnal Fizicheskoj Khimii, 1952, vol. 26, p. 1298

  摘要：

  DOI：

文献信息

• Mononuclear iron complex and organic synthesis reaction using same
  申请人：KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION

  公开号：US10363551B2

  公开（公告）日：2019-07-30

  A mononuclear iron bivalent complex having iron-silicon bonds, which is represented by formula (1), can exhibit an excellent catalytic activity in at least one reaction selected from three reactions, i.e., a hydrosilylation reaction, a hydrogenation reaction and a reaction for reducing a carbonyl compound. (In the formula, R1 to R6 independently represent a hydrogen atom, an alkyl group which may be substituted by X, or the like; X represents a halogen atom, or the like; L1 represents at least one two-electron ligand selected from an isonitrile ligand, an amine ligand, an imine ligand, a nitrogenated heterocyclic ring, a phosphine ligand, a phosphite ligand and a sulfide ligand, wherein, when multiple L1's are present, two L1's may be bonded to each other; L2 represents a two-electron ligand that is different from a CO ligand or the above-mentioned L1, wherein, when multiple L2's are present, two L2's may be bonded to each other; and m1 represents an integer of 1 to 4 and m2 represents an integer of 0 to 3, wherein the sum total of m1 and m2 (i.e., m1+m2) satisfies 3 or 4.)

  具有铁-硅键的单核二价铁络合物，其由公式（1）表示，可以在三个反应中选择至少一个反应表现出优异的催化活性，即硅氢化反应、氢化反应和还原羰基化合物的反应。 （在公式中，R1至R6独立代表氢原子、可能被X取代的烷基团等；X代表卤素原子等；L1代表至少一种从异腈配体、胺配体、亚胺配体、氮杂环、膦配体、亚磷酸盐配体和硫化物配体中选择的两电子配体，其中，当存在多个L1时，两个L1可以相互连接；L2代表与CO配体或上述L1不同的两电子配体，其中，当存在多个L2时，两个L2可以相互连接；m1代表1至4的整数，m2代表0至3的整数，其中m1和m2的总和（即m1+m2）满足3或4。）
• MONONUCLEAR IRON COMPLEX AND ORGANIC SYNTHESIS REACTION USING SAME
  申请人：KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION

  公开号：US20160023196A1

  公开（公告）日：2016-01-28

  Provided is a mononuclear iron complex that comprises an iron-silicon bond that is represented by formula (1) and that exhibits excellent catalyst activity in each of a hydrosilylation reaction, a hydrogenation reaction, and reduction of a carbonyl compound. In formula (1), R 1 -R 6 either independently represent an alkyl group, an aryl group, an aralkyl group or the like that may be substituted with a hydrogen atom or X, or represent a crosslinking substituent in which at least one pair comprising one of R 1 -R 3 and one of R 4 -R 6 is combined. X represents a halogen atom, an organoxy group, or the like. L represents a two-electron ligand other than CO. When a plurality of L are present, the plurality of L may be the same as or different from each other. When two L are present, the two L may be bonded to each other. n and m independently represent an integer of 1 to 3 with the stipulation that n+m equals 3 or 4.

  提供的是一种含有铁硅键的单核铁配合物，其由式（1）表示，并且在氢硅烷基化反应、加氢反应和醛类化合物还原反应中表现出优异的催化活性。 在式（1）中，R1-R6分别独立表示可以用氢原子或X取代的烷基、芳基、芳基烷基等，或表示至少包括一个由R1-R3和一个由R4-R6组成的一对的交联取代基。X表示卤素原子、有机氧基等。L表示除CO之外的双电子配体。当存在多个L时，这些L可以相同也可以不同。当存在两个L时，这两个L可以与彼此相连。n和m分别表示1到3的整数，且n+m等于3或4。
• ABUSE DETERRENT AND ANTI-DOSE DUMPING PHARMACEUTICAL SALTS USEFUL FOR THE TREATMENT OF ATTENTION DEFICIT/HYPERACTIVITY DISORDER
  申请人：King Clifford Riley

  公开号：US20120028960A1

  公开（公告）日：2012-02-02

  A pharmaceutical composition comprising a drug substance consisting essentially of a pharmaceutically acceptable organic acid addition salt of an amine containing pharmaceutically active compound wherein the amine containing pharmaceutical active compound is selected from the group consisting of racemic or single isomer ritalinic acid or phenethylamine derivatives and the drug substance has a physical form selected from amorphous and polymorphic.

  一种药物组合物，包括基本上由含有药用活性化合物的胺的药用可接受的有机酸加合盐组成的药物物质，其中含有药用活性化合物的胺被选择自光学异构体或单异构体利他林酸或苯乙胺衍生物的群体，并且该药物物质具有从无定形到多型的物理形式。
• PROCESS FOR PREPARATION OF NORBORNENE DERIVATIVES
  申请人：JX Nippon Oil & Energy Corporation

  公开号：EP2444386A1

  公开（公告）日：2012-04-25

  A method for producing a norbornene derivative, comprising: a first step of forming a Mannich base by reacting a carbonyl compound and an amine compound with each other in an acidic solvent, to thereby obtain a reaction liquid comprising the Mannich base in the acidic solvent, the acidic solvent comprising a formaldehyde derivative and 0.01 mol/L or more of an acid represented by the formula: HX (In the formula, X represents F or the like), the carbonyl compound being represented by any of the following general formulae (1) to (3): [in formulae (1) to (3), R1, R2, R3, R4, R5, and R6 each independently represent a hydrogen atom or the like, and n represents an integer of any of 0 to 4], the amine compound being represented by the following general formula (4): [in the formula (4), R7S each independently represent a linear chain saturated hydrocarbon group having 1 to 20 carbon atoms or the like, and X- represents F- or the like], the Mannich base being represented by any of the following general formulae (5) to (7): [R1, R2, R3, R4, R5, R6, and n in the formulae (5) to (7) have the same meanings as those of R1, R2, R3, R4, R5, R6, and n in the formulae (1) to (3), and R7 and X- in the formulae (5) to (7) have the same meanings as those of R7 and X- in the formula (4)] and a second step of reacting the Mannich base and a diene compound with each other by adding an organic solvent, a base in an amount of 1.0 to 20.0 equivalents to the acid, and the diene compound to the reaction liquid, and then heating the reaction liquid, to thereby form a norbornene derivative, the diene compound being represented by the following general formula (8): [in the formula (8), R8 represents a hydrogen atom or the like], the norbornene derivative being represented by any of the following general formulae (9) to (11): [R1, R2, R3, R4, R5, R6, and n in the formulae (9) to (11) have the same meanings as those of R1, R2, R3, R4, R5, R6, and n in the formulae (1) to (3), and R8 in the formulae (9) to (11) has the same meaning as that of R8 in the formula (8)].

  一种制备去氢莰烯衍生物的方法，包括以下步骤：第一步，在酸性溶剂中使羰基化合物和胺基化合物反应，形成曼尼希碱，从而在酸性溶剂中获得包含曼尼希碱的反应液，所述酸性溶剂包括甲醛衍生物和代表为HX的酸，其中HX中的X代表F或类似物，所述羰基化合物由以下通式（1）至（3）中的任一通式表示：[在通式（1）至（3）中，R1、R2、R3、R4、R5和R6各自独立地代表氢原子或类似物，n代表0至4中的任一整数]，所述胺基化合物由以下通式（4）表示：[在通式（4）中，R7S各自独立地代表具有1至20个碳原子或类似物的线性链饱和碳氢基团，X-代表F-或类似物]，所述曼尼希碱由以下通式（5）至（7）中的任一通式表示：[在通式（5）至（7）中，R1、R2、R3、R4、R5、R6和n的含义与通式（1）至（3）中的R1、R2、R3、R4、R5、R6和n的含义相同，通式（5）至（7）中的R7和X-的含义与通式（4）中的R7和X-的含义相同]；第二步，通过向反应液中加入有机溶剂、相当于酸的1.0至20.0当量的碱和二烯化合物，然后加热反应液，使曼尼希碱与二烯化合物发生反应，从而形成去氢莰烯衍生物，所述二烯化合物由以下通式（8）表示：[在通式（8）中，R8代表氢原子或类似物]，所述去氢莰烯衍生物由以下通式（9）至（11）中的任一通式表示：[在通式（9）至（11）中，R1、R2、R3、R4、R5、R6和n的含义与通式（1）至（3）中的R1、R2、R3、R4、R5、R6和n的含义相同，通式（9）至（11）中的R8的含义与通式（8）中的R8的含义相同]。
• Sequential hydroaminomethylation/Pd-catalyzed hydrogenolysis as an atom efficient route to valuable primary and secondary amines
  作者：Jacquin October、Selwyn F. Mapolie

  DOI：10.1016/j.tetlet.2021.153018

  日期：2021.4

  valuable primary and secondary amines is reported using a sequential procedure of hydroaminomethylation and Pd-catalyzed hydrogenolysis. The hydroaminomethylation reaction was catalyzed by a cationic Rh(I) iminopyridyl complex and the N-alkylated benzylamines were produced with high chemoselectivity, albeit as mixtures of linear and branched products. Performing the hydrogenolysis reaction using 10% Pd/C

  使用氢氨基甲基化和 Pd 催化氢解的顺序程序报道了有价值的伯胺和仲胺的简单合成。氢氨基甲基化反应由阳离子 Rh（I） 亚氨基吡啶络合物催化，并且产生具有高化学选择性的 N-烷基化苄胺，尽管是线性和支链产物的混合物。使用 10% Pd/C 进行氢解反应，提供了有价值的伯胺和仲胺，这些胺可用于表面活性剂、制药和聚合物行业。