7-amino-8-((4'-((diphenoxyphosphoryl)(pyridin-3-yl)methylamino)biphenyl-4-yl)diazenyl)-4-hydroxynaphthalene-2-sulfonic acid | 1392848-75-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 7-amino-8-((4'-((diphenoxyphosphoryl)(pyridin-3-yl)methylamino)biphenyl-4-yl)diazenyl)-4-hydroxynaphthalene-2-sulfonic acid
• 英文别名: 7-Amino-8-[[4-[4-[[diphenoxyphosphoryl(pyridin-3-yl)methyl]amino]phenyl]phenyl]diazenyl]-4-hydroxynaphthalene-2-sulfonic acid
• CAS: 1392848-75-7
• 化学式: C₄₀H₃₂N₅O₇PS
• 分子量: 757.763
• InChiKey: ARNWGAPNHFHZMD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.7
• 重原子数：
  54
• 可旋转键数：
  12
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.03
• 拓扑面积：
  194
• 氢给体数：
  4
• 氢受体数：
  12

反应信息

• 作为产物：
  描述：

  联苯胺 在 盐酸 、 四氯化钛 、 sodium nitrite 作用下， 以 二氯甲烷 、 水 为溶剂， 反应 26.5h， 生成 7-amino-8-((4'-((diphenoxyphosphoryl)(pyridin-3-yl)methylamino)biphenyl-4-yl)diazenyl)-4-hydroxynaphthalene-2-sulfonic acid
  参考文献：
  名称：

  Antimicrobial Activities of a Series of Diphenyl (4′-(Aryldiazenyl)Biphenyl-4-Ylamino)(Pyridin-3-YL)Methylphosphonates

  摘要：

  A series of diphenyl (4'-(aryldiazenyl)biphenyl-4-ylamino)(pyridin-3-yl)methylphosphonates 2-7 was synthesized in high yields and their antimicrobial activities were investigated. Some compounds showed high antimicrobial activities against Escherichia coli as a gram-negative bacterium, Bacillus subtilis and Staphylococcus aureus as gram-positive bacteria, and Candida albicans and Schccaromycies cerevisiae as fungi and at low concentrations (10-1000 mu g/mL). Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file.

  DOI：

  10.1080/10426507.2012.680084