trans-2-oxadecalin

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: trans-2-oxadecalin
• 英文别名: (+/-)-trans-Hexahydro-isochroman；(4aR,8aS)-3,4,4a,5,6,7,8,8a-octahydro-1H-isochromene
• 化学式: C₉H₁₆O
• 分子量: 140.225
• InChiKey: LALXVXZHYIIWQP-RKDXNWHRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  trans-2-oxadecalin 在 氢溴酸 作用下， 生成 trans-1-bromomethyl-2-(2-bromoethyl)cyclohexane
  参考文献：
  名称：

  PREPARATION AND PHYSICAL PROPERTIES OF SULFUR COMPOUNDS RELATED TO PETROLEUM. IV. cis- AND trans-2-THIAHYDRINDAN AND 2-THIADECALIN

  摘要：

  DOI：

  10.1021/jo01374a007
• 作为产物：
  描述：

  异色满 在 镍 作用下， 200.0~230.0 ℃ 、12.26 MPa 条件下， 生成 trans-2-oxadecalin 、 (+/-)-cis-Hexahydro-isochroman
  参考文献：
  名称：

  PREPARATION AND PHYSICAL PROPERTIES OF SULFUR COMPOUNDS RELATED TO PETROLEUM. IV. cis- AND trans-2-THIAHYDRINDAN AND 2-THIADECALIN

  摘要：

  DOI：

  10.1021/jo01374a007

文献信息

• [EN] NON-SYMMETRICAL GELLING AGENT<br/>[FR] AGENT DE GELIFICATION NON SYMETRIQUE
  申请人：APPLIED NANO SYSTEMS B V

  公开号：WO2005047231A1

  公开（公告）日：2005-05-26

  The present invention relates to a novel trisubstituted cyclic thickener or gelator. The present invention further relates to a method for thickening or gelating a solution comprising the use of such a gelator or thickener. A gelator or thickener according to the invention may for instance be used for pharmaceutical or cosmetic purposes. It may further be used as a support material in chromatographic materials or catalytically active materials.

  本发明涉及一种新型的三取代环状增稠剂或凝胶剂。本发明还涉及一种利用该凝胶剂或增稠剂增稠或凝胶化溶液的方法。根据本发明的凝胶剂或增稠剂可能用于制药或化妆品目的。它还可以用作色谱材料或催化活性材料的支撑材料。
• Gelling agents
  申请人：Applied NanoSystems B.V.

  公开号：EP1364941A1

  公开（公告）日：2003-11-26

  The invention relates to a novel class of gelling agents, to a process of preparing said agents, to the use of said agents to prepare gels, and to the gels thus obtained. A gelling agent or thickener according to the invention comprises a rigid core which is functionalized with three amino acid ester or amide groups by means of an amide or urea linkage. It may be used to gelate or thicken numerous solvents.

  该发明涉及一种新型凝胶剂类别，一种制备该剂的方法，使用该剂来制备凝胶，以及由此获得的凝胶。根据该发明，一种凝胶剂或增稠剂包括通过酰胺或脲键与三个氨基酸酯或酰胺基团功能化的刚性核心。它可以用于凝胶或增稠许多溶剂。
• Production of small particles
  申请人：Friggeri Arianna

  公开号：US20060099270A1

  公开（公告）日：2006-05-11

  The present invention relates to a method for producing particles of a compound of interest. In a method according to the invention a solution is provided of the compound of interest in a solvent. This solution is thickened or gelled and particles are formed. The invention further relates to a particle that is obtainable by the invention.

  本发明涉及一种生产相关化合物颗粒的方法。根据本发明的方法，在溶剂中提供相关化合物的溶液。该溶液经浓缩或胶化后形成颗粒。本发明还涉及一种可通过本发明获得的颗粒。
• Synthesis of 3-substituted trans-2-oxadecalins and 1-substituted trans-2-oxahydrindanes
  作者：N. P. Volynskii、O. L. Alikhanova

  DOI：10.1007/bf01172270

  日期：1991.8

  A study was carried out of the intramolecular cyclization of trans-1-methoxy-methyl-2-(1-hydroxyalkyl)cyclohexanes and trans-1-methoxymethyl-2-(2-hydroxy-alkyl) cyclohexanes by the action of acid chlorides of phosphorous, sulfurous and p-toluenesulfonic acids with the formation of 1-substituted trans-2-oxa-hydrindanes in low yields and 3-substituted trans-2-oxadecalins in high yields. A relationship has been established between the yields of the cyclization products and the nature of the halogenating agent. The cyclization does not proceed via an intermediate oxonium ion, but by means of an intermolecular electronic transition.
• GELLING AGENTS
  申请人：Applied NanoSystems B.V.

  公开号：EP1506168B1

  公开（公告）日：2008-04-30