5,7-Difluoro-2-propyl-6-(3,4,5-trifluorophenyl)-1,2,3,4-tetrahydronaphthalene

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 5,7-Difluoro-2-propyl-6-(3,4,5-trifluorophenyl)-1,2,3,4-tetrahydronaphthalene
• 化学式: C₁₉H₁₇F₅
• 分子量: 340.336
• InChiKey: NWEYLFKXORNYIJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.8
• 重原子数：
  24
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.37
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  5,7-二氟-3,4-二氢-1H-2-萘酮 在 正丁基锂 作用下， 生成 5,7-Difluoro-2-propyl-6-(3,4,5-trifluorophenyl)-1,2,3,4-tetrahydronaphthalene
  参考文献：
  名称：

  Design, Synthesis and Physical Properties of New Liquid Crystal Materials Having a Fluoro-Substituted Tetrahydronaphthalene Structure for Active Matrix LCD

  摘要：

  Liquid crystal materials having a fluoro-substituted tetralhydro-naphthalene structure were designed for active matrix LCD. 6-Aryl-5-fluoro-1,2,3,4-tetrahydronaphthalenes and 5,6-difluro-1,2,3,4-tetrahydronaphthalenes were prepared by regioselective fluorination and hydrogenation of 2-naphthols. 6-Aryl-5,7-difluoro-1,2,3,4-tetrahydronaphthalenes were synthesized from 5,7-difluoro-1,2,3,4-tetrahydronaphthalene-2-one. The liquid crystal mixture containing these compounds with very good co-solubility exhibits a wide nematic temperature range with low melting point and very large value of dielectric anisotropy. From these results these compounds are useful for design. of new liquid crystal mixtures for TFT-displays.

  DOI：

  10.1080/15421400490434973

文献信息

• COMPOSITE LIQUID CRYSTAL COMPOSITION, DISPLAY ELEMENT AND ELECTRIC FIELD DETECTOR
  申请人：DIC CORPORATION

  公开号：US20160298035A1

  公开（公告）日：2016-10-13

  Provided is a composite liquid crystal composition which contains a liquid crystal compound and a polymerizable compound, has sufficiently high Δn, further has high photostability, and can constitute a liquid crystal device capable of being driven at a low voltage. The composite liquid crystal composition includes, as the liquid crystal compound, a compound having a biphenyl skeleton and two or more compounds represented by Formula (I-a), in which the content of the compound having a biphenyl skeleton is 20% by mass or less of the liquid crystal compounds, and the content of the compound represented by Formula (I-a) in which C 1 represents a 1,4-cyclohexylene group and n 1 is not 0 is 45% by mass or more of the liquid crystal compounds; and as the polymerizable compound, one or more compounds selected from the compounds represented by Formulas (II-a1) and (II-a2) and a compound represented by (II-b), in which the total content of the liquid crystal compounds is 65% to 85% by mass, and the total content of the polymerizable compounds is 15% to 35% by mass.
• US7198827B1
  申请人：——

  公开号：US7198827B1

  公开（公告）日：2007-04-03
• US9914878B2
  申请人：——

  公开号：US9914878B2

  公开（公告）日：2018-03-13
• Design, Synthesis and Physical Properties of New Liquid Crystal Materials Having a Fluoro-Substituted Tetrahydronaphthalene Structure for Active Matrix LCD
  作者：Tetsuo Kusumoto、Yoshitaka Saito、Yutaka Nagashima、Makoto Negishi、Sadao Takehara、Yoshinori Iwashita、Kiyofumi Takeuchi、Haruyoshi Takatsu、Corneria Pithart、Rainer Frings、Artur Lachowicz、Gerwald Grahe

  DOI：10.1080/15421400490434973

  日期：2004.1

  Liquid crystal materials having a fluoro-substituted tetralhydro-naphthalene structure were designed for active matrix LCD. 6-Aryl-5-fluoro-1,2,3,4-tetrahydronaphthalenes and 5,6-difluro-1,2,3,4-tetrahydronaphthalenes were prepared by regioselective fluorination and hydrogenation of 2-naphthols. 6-Aryl-5,7-difluoro-1,2,3,4-tetrahydronaphthalenes were synthesized from 5,7-difluoro-1,2,3,4-tetrahydronaphthalene-2-one. The liquid crystal mixture containing these compounds with very good co-solubility exhibits a wide nematic temperature range with low melting point and very large value of dielectric anisotropy. From these results these compounds are useful for design. of new liquid crystal mixtures for TFT-displays.