3-hydroxy-butyric acid-[1]naphthylamide | 96328-04-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 3-hydroxy-butyric acid-[1]naphthylamide
• 英文别名: 3-Hydroxy-buttersaeure-[1]naphthylamid；3-hydroxy-N-naphthalen-1-ylbutanamide
• CAS: 96328-04-0
• 化学式: C₁₄H₁₅NO₂
• 分子量: 229.279
• InChiKey: DRYOCDANNUYLRY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  49.3
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  β-丁内酯 、 1-萘胺 在 苯 作用下， 生成 3-hydroxy-butyric acid-[1]naphthylamide
  参考文献：
  名称：

  Iwakura et al., Nippon Kagaku Zasshi, 1954, vol. 75, p. 315,318

  摘要：

  DOI：

文献信息

• Method for preparing optically active beta-butyrolactones
  申请人：Watanabe Shinya

  公开号：US20060046286A1

  公开（公告）日：2006-03-02

  The present invention is to provide a method for preparing easily and efficiently β-butyrolactones and/or optically active 3-hydroxycarboxylic acid derivatives in high optical purity by use of an easily available hydrolase, which are useful as intermediates for pharmaceuticals, agrochemicals and the like. More particularly, the present invention relates to a method for preparing β-butyrolactones and/or optically active 3-hydroxycarboxylic acid derivatives with an optical purity of substantially 100% ee, comprising reacting a β-butyrolactone which is a mixture of optical isomers, with a nucleophilic agent in the presence of a hydrolase, provided that a lipase derived from porcine pancreas is excluded.

  本发明提供了一种使用易得的水解酶高效制备β-丁内酯和/或高光学纯度的光学活性3-羟基羧酸衍生物的方法，这些衍生物作为制药、农药等中间体具有应用价值。更具体地说，本发明涉及一种制备β-丁内酯和/或光学活性3-羟基羧酸衍生物的方法，其光学纯度达到实质上100% ee，包括在水解酶的存在下，用亲核试剂反应混合光学异构体的β-丁内酯，但不包括来自猪胰脂肪酶的酶。
• Starch-(Meth)Acrylate Graft Copolymer, Oil-Swellable Material and Oil- and Water-Swellable Material Comprising the Same, and Sealing Articles and Packers Prepared from said Swellable Material
  申请人：Wang Qiang

  公开号：US20090131563A1

  公开（公告）日：2009-05-21

  The present invention provides a starch-(meth)acrylate graft copolymer and the preparation process thereof. The starch-(meth)acrylate graft copolymer is prepared by copolymerizing (meth)acrylate monomer and starch in a weight ratio of (0.4˜8):1, the graft copolymer having a skeleton of large starch molecule is grafted with one or more (meth)acrylate monomer with a grafting ratio of no less than 70%. The present invention further provides an oil swellable material, which comprises the starch-(meth)acrylate graft copolymer above as the swelling agent; and also an oil- and water-swellable material, which comprises the starch-(meth)acrylate graft copolymer above, water absorbing agent, reactive monomer, surfactant and material matrix. Further, sealing articles and packers prepared from the above oil swellable material and oil- and water-swellable material are also provided.
• US8053509B2
  申请人：——

  公开号：US8053509B2

  公开（公告）日：2011-11-08
• Iwakura et al., Nippon Kagaku Zasshi, 1954, vol. 75, p. 315,318
  作者：Iwakura et al.

  DOI：——

  日期：——