2,2,5,5-四甲基哌嗪 | 5434-90-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪烷类
• 中文名称: 2,2,5,5-四甲基哌嗪
• 中文别名: 2,2,5,5-四甲基哌嗪双盐酸盐；2,2,5,5-四甲基哌嗪.2HCL
• 英文名称: 2,2,5,5-tetramethyl-piperazine
• 英文别名: 2,2,5,5-Tetramethyl-piperazin；2,2,5,5-tetramethylpiperazine
• CAS: 5434-90-2
• 化学式: C₈H₁₈N₂
• 分子量: 142.244
• InChiKey: QOBFZPNAUHORDW-UHFFFAOYSA-N

物化性质

• 熔点：
  85-87℃
• 沸点：
  176-183℃
• 密度：
  0.811±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  24.1
• 氢给体数：
  2
• 氢受体数：
  2

安全信息

• 海关编码：
  2933599090

反应信息

• 作为反应物：
  描述：

  2,2,5,5-四甲基哌嗪 在 1,4-二氧六环 、 copper oxide-chromium oxide barium oxide 、 sodium carbonate 、 苯 作用下， 生成 2-(2,2,5,5-tetramethyl-piperazino)-ethanol
  参考文献：
  名称：

  1,4-Diazabicyclo[2.2.2]octanes and 1,5-Diazabicyclo[3.2.2]nonanes from Piperazines and Homopiperazines

  摘要：

  DOI：

  10.1021/ja01633a057
• 作为产物：
  描述：

  2-氨基-2-甲基-1-丙醇 在 氨 、 氢气 、 镍 作用下， 200.0 ℃ 、6.86 MPa 条件下， 生成 2,2,5,5-四甲基哌嗪
  参考文献：
  名称：

  1,4-Diazabicyclo[2.2.2]octanes and 1,5-Diazabicyclo[3.2.2]nonanes from Piperazines and Homopiperazines

  摘要：

  DOI：

  10.1021/ja01633a057

文献信息

• Salts of triazine compounds with cyanuric acid as flame retardants
  申请人：MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA

  公开号：EP0550084A1

  公开（公告）日：1993-07-07

  Salts of triazine compounds with cyanuric acid, of general formula (I): obtained by salifying 2,4,6-triamino-1,3,5-triazine derivatives with cyanuric acid. The new salts of general formula (I) are used in particular as flame retardant additives.

  三嗪类化合物与三聚氰酸的盐，通式为(I)：通过使用三聚氰酸与2,4,6-三氨基-1,3,5-三嗪衍生物进行盐化反应而获得。新的通式(I)盐特别用作阻燃添加剂。
• Piperazine derivatives as chain extenders in polyurea elastomer systems
  申请人：Texaco Chemical Co.

  公开号：US05082917A1

  公开（公告）日：1992-01-21

  A polyurea elastomer is disclosed. The elastomer includes an isocyanate, an amine terminated polyoxyalkylene polyol, and a chain extender. The isocyanate is preferably a quasi-prepolymer of an isocyanate and a material selected from at least one polyol, a high molecular weight polyoxyalkyleneamine or a combination thereof. The chain extender includes a minor amount of a tetraalkylpiperazine and a major amount of diethyltoluenediamine. A one-step method of making the tetraalkylpiperazine and tetraalkylpiperazinone is also disclosed. The method includes reacting a 2-amino-2-alkyl-1-alkanol in the presence of a nickel-iron-copper-manganese catalyst.

  本发明涉及一种聚氨酯弹性体。该弹性体包括异氰酸酯，末端带有氨基的聚氧烷基多元醇和链延长剂。所述异氰酸酯优选为异氰酸酯和至少一种聚醇、高分子量聚氧烷基胺或两者的组合物的准预聚物。链延长剂包括少量四烷基哌嗪和大量二乙基甲苯二胺。本发明还公开了一种制备四烷基哌嗪和四烷基哌嗪酮的一步法。该方法包括在镍-铁-铜-锰催化剂的存在下反应2-氨基-2-烷基-1-醇。
• Piperazine derivatives as chain extenders in polyurea elastomer systems and method of making same
  申请人：TEXACO CHEMICAL COMPANY

  公开号：EP0459673A2

  公开（公告）日：1991-12-04

  Polyurea elastomers are produced by reacting an isocyanate with an amine-terminated polyoxyalkylene polyol in the presence of a chain extender according to the invention, the chain extender comprises a minor amount of tetraalkylpiperazine, preferably tetramethyl piperazine, and a major amount of diethyl toluene diamine. The invention also provides a method for synthesizing tetraalkylpiperazines simultaneously with tetraalkylpiperazinones, by reacting a 2-amino-2-alkyl-1-alkanol in the presence of a nickel plus transition metal catalyst.

  根据本发明，聚脲弹性体是通过异氰酸酯与胺封端聚氧亚烷基多元醇在扩链剂存在下反应制得的，扩链剂包括少量的四烷基哌嗪（最好是四甲基哌嗪）和大量的二乙基甲苯二胺。 本发明还提供了一种同时合成四烷基哌嗪和四烷基哌嗪酮的方法，即在镍加过渡金属催化剂存在下，使 2-氨基-2-烷基-1-烷醇发生反应。
• Melaminic polycondensates
  申请人：MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA

  公开号：EP0542360A1

  公开（公告）日：1993-05-19

  Condensation compounds obtained by means of the polymerization of polyaminic compositions essentially constituted by derivatives of 2,4,6-triamino-1,3,5-triazine having the general formula (I): with aldehydes, preferably formaldehyde.

  通过聚合主要由具有通式 (I) 的 2,4,6-三氨基-1,3,5-三嗪衍生物构成的多氨基组合物而获得的缩合化合物： 与醛（最好是甲醛）的缩合物。
• Self-extinguishing polymeric compositions
  申请人：MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA

  公开号：EP0542369A1

  公开（公告）日：1993-05-19

  Self-extinguishing polymeric compositions comprising ammonium polyphosphate having the general formula (I): microencapsulated with condensation compounds obtained by means of the polymerization of polyaminic compositions essentially constituted by derivatives of 2,4,6-triamino-1,3,5- triazine, having the general formula (II): with aldehydes, preferably formaldehyde.

  自熄灭聚合物组合物，包含通式为(I)的聚磷酸铵： 与通过聚合基本上由 2，4，6-三氨基-1，3，5-三嗪的衍生物构成的聚氨基组合物（通式为 (II)）而获得的缩合化合物微囊化： 与醛（最好是甲醛）聚合而成。