1-fluoro-6-propyl-2-naphthol | 247924-39-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 1-fluoro-6-propyl-2-naphthol
• 英文别名: 1-fluoro-6-propylnaphthalen-2-ol
• CAS: 247924-39-6
• 化学式: C₁₃H₁₃FO
• 分子量: 204.244
• InChiKey: ODWMPTMWRTZGCF-UHFFFAOYSA-N

物化性质

• 沸点：
  324.3±22.0 °C(Predicted)
• 密度：
  1.163±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1-fluoro-6-propyl-2-naphthol 在 palladium on activated charcoal 氢气 作用下， 生成 2-propyl-5-fluoro-1,2,3,4-tetrahydro-6-naphthol
  参考文献：
  名称：

  Design, Synthesis and Physical Properties of New Liquid Crystal Materials Having a Fluoro-Substituted Tetrahydronaphthalene Structure for Active Matrix LCD

  摘要：

  Liquid crystal materials having a fluoro-substituted tetralhydro-naphthalene structure were designed for active matrix LCD. 6-Aryl-5-fluoro-1,2,3,4-tetrahydronaphthalenes and 5,6-difluro-1,2,3,4-tetrahydronaphthalenes were prepared by regioselective fluorination and hydrogenation of 2-naphthols. 6-Aryl-5,7-difluoro-1,2,3,4-tetrahydronaphthalenes were synthesized from 5,7-difluoro-1,2,3,4-tetrahydronaphthalene-2-one. The liquid crystal mixture containing these compounds with very good co-solubility exhibits a wide nematic temperature range with low melting point and very large value of dielectric anisotropy. From these results these compounds are useful for design. of new liquid crystal mixtures for TFT-displays.

  DOI：

  10.1080/15421400490434973
• 作为产物：
  描述：

  6-丙基-2-萘酚 在 N,N’-difluoro-2,2’-bipyridinium bis(tetrafluoroborate) 作用下， 生成 1-fluoro-6-propyl-2-naphthol
  参考文献：
  名称：

  Design, Synthesis and Physical Properties of New Liquid Crystal Materials Having a Fluoro-Substituted Tetrahydronaphthalene Structure for Active Matrix LCD

  摘要：

  Liquid crystal materials having a fluoro-substituted tetralhydro-naphthalene structure were designed for active matrix LCD. 6-Aryl-5-fluoro-1,2,3,4-tetrahydronaphthalenes and 5,6-difluro-1,2,3,4-tetrahydronaphthalenes were prepared by regioselective fluorination and hydrogenation of 2-naphthols. 6-Aryl-5,7-difluoro-1,2,3,4-tetrahydronaphthalenes were synthesized from 5,7-difluoro-1,2,3,4-tetrahydronaphthalene-2-one. The liquid crystal mixture containing these compounds with very good co-solubility exhibits a wide nematic temperature range with low melting point and very large value of dielectric anisotropy. From these results these compounds are useful for design. of new liquid crystal mixtures for TFT-displays.

  DOI：

  10.1080/15421400490434973

文献信息

• Naphthalene derivative and liquid crystal composition comprising the same
  申请人：Dainippon Ink and Chemicals, Inc.

  公开号：US20030136944A1

  公开（公告）日：2003-07-24

  Disclosed in a novel liquid-crystalline compound which is a naphthalene derivative useful as an electro-optical liquid crystal display material, a liquid crystal composition containing such naphthalene derivatives and a liquid crystal display device comprising the same. The naphthalene derivative provided by the present invention exhibits an excellent liquid-crystallinity and miscibility with currently widely used liquid crystal compositions or compositions. The addition of the naphthalene derivative makes it possible to drastically lower the threshold voltage of the liquid crystal composition while maintaining its high response. The naphthalene derivative of the present invention is characterized by a large birefringence index. Further, most of the naphthalene derivative of the present invention has no strongly polar group in its molecule and thus can also be used for active matrix driving. Moreover, as shown in the foregoing examples, the naphthalene derivative of the present invention can be easily produced and is colorless and chemically stable. Accordingly, the liquid crystal composition comprising the naphthalene derivative of the present invention is extremely useful as a practical liquid crystal composition, particularly a liquid crystal composition which can operate within a wide temperature range and requires a high speed response and a low voltage driving.

  本发明揭示了一种新型液晶化合物，该化合物是萘衍生物，可用作电光液晶显示材料，液晶组合物包含这种萘衍生物，以及包含它的液晶显示装置。本发明提供的萘衍生物表现出优异的液晶性和与目前广泛使用的液晶组合物或配方的混溶性。添加萘衍生物可以在保持高响应的同时大幅降低液晶组合物的阈值电压。本发明的萘衍生物具有较大的双折射率指数。此外，大多数本发明的萘衍生物分子中没有强极性基团，因此也可用于有源矩阵驱动。此外，正如前面的例子所示，本发明的萘衍生物可以很容易地制备，无色且化学稳定。因此，包含本发明的萘衍生物的液晶组合物非常有用作为实用的液晶组合物，特别是需要在广泛的温度范围内工作并需要高速响应和低电压驱动的液晶组合物。
• Design, Synthesis and Physical Properties of New Liquid Crystal Materials for Active Matrix LCD (2)
  作者：Makoto Negishi、Shinji Ogawa、Masashi Osawa、Tatsuo Kawara、Tetsuo Kusumoto、Kiyofumi Takeuchi、Sadao Takehara、Haruyoshi Takatsu

  DOI：10.1080/10587250108025059

  日期：2001.8

  Novel 1-fluoro- and 1,2-difluoronaphthalene derivatives were designed for active matrix LCD and were prepared through the regioselective fluorination of 6-substituted 2-naphthols. These compounds exhibited high nematic-isotropic transition temperatures with very large dielectric anisotropy and large birefringences. These results are useful for design of new liquid crystal mixtures for TFT-displays.
• US6468607B1
  申请人：——

  公开号：US6468607B1

  公开（公告）日：2002-10-22
• US7145047B2
  申请人：——

  公开号：US7145047B2

  公开（公告）日：2006-12-05
• Design, Synthesis and Physical Properties of New Liquid Crystal Materials Having a Fluoro-Substituted Tetrahydronaphthalene Structure for Active Matrix LCD
  作者：Tetsuo Kusumoto、Yoshitaka Saito、Yutaka Nagashima、Makoto Negishi、Sadao Takehara、Yoshinori Iwashita、Kiyofumi Takeuchi、Haruyoshi Takatsu、Corneria Pithart、Rainer Frings、Artur Lachowicz、Gerwald Grahe

  DOI：10.1080/15421400490434973

  日期：2004.1

  Liquid crystal materials having a fluoro-substituted tetralhydro-naphthalene structure were designed for active matrix LCD. 6-Aryl-5-fluoro-1,2,3,4-tetrahydronaphthalenes and 5,6-difluro-1,2,3,4-tetrahydronaphthalenes were prepared by regioselective fluorination and hydrogenation of 2-naphthols. 6-Aryl-5,7-difluoro-1,2,3,4-tetrahydronaphthalenes were synthesized from 5,7-difluoro-1,2,3,4-tetrahydronaphthalene-2-one. The liquid crystal mixture containing these compounds with very good co-solubility exhibits a wide nematic temperature range with low melting point and very large value of dielectric anisotropy. From these results these compounds are useful for design. of new liquid crystal mixtures for TFT-displays.