N-4-t-butylbenzoyl-N-{2-[4-(2-ethoxyethyl)-2-methylphenoxy]ethyl}-4-chloro-1,3-dimethyl-5-pyrazolecarboxamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: N-4-t-butylbenzoyl-N-{2-[4-(2-ethoxyethyl)-2-methylphenoxy]ethyl}-4-chloro-1,3-dimethyl-5-pyrazolecarboxamide
• 英文别名: N-(4-tert-butylbenzoyl)-4-chloro-N-[2-[4-(2-ethoxyethyl)-2-methylphenoxy]ethyl]-2,5-dimethylpyrazole-3-carboxamide
• 化学式: C₃₀H₃₈ClN₃O₄
• 分子量: 540.102
• InChiKey: ORLHGOUHNGKRON-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.7
• 重原子数：
  38
• 可旋转键数：
  11
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  73.7
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  N-{2-[4-(2-ethoxyethyl)-2-methylphenoxy]-ethyl}-4-chloro-1,3-dimethyl-5-pyrazolecarboxamide 、 2-叔丁基苯甲酰氯 以 水 、 甲苯 为溶剂， 生成 N-4-t-butylbenzoyl-N-{2-[4-(2-ethoxyethyl)-2-methylphenoxy]ethyl}-4-chloro-1,3-dimethyl-5-pyrazolecarboxamide
  参考文献：
  名称：

  Phenoxyalkylamine derivative and agricultural and horticultural chemical

  摘要：

  本发明涉及一种由以下式（I）表示的苯氧基烷胺化合物：其中R.sup.1是C.sub.1-8烷基，C.sub.3-8环烷基，氢原子，苯基或C.sub.1-4卤代烷基；R.sup.2是卤原子，氢原子，C.sub.1-4烷基，C.sub.1-4烷氧基或硝基；R.sup.1和R.sup.2可以彼此连接并缩合成吡唑环以形成饱和的4-至8-成员环；R.sup.3是C.sub.1-15烷基，C.sub.3-8环烷基，苯基，C.sub.1-4卤代烷基，C.sub.2-8烷氧基烷基，C.sub.3-6烯基，吡啶基，苄基，C.sub.3-8烷氧羰基烷基，吡唑基或C.sub.1-4烷氧基；R.sup.4是C.sub.1-4烷基，氢原子或卤原子；R.sup.5是C.sub.1-20烷基，氢原子，C.sub.3-6烯基，苄基，苯氧基，卤原子，氰甲基或--A--O--R.sup.7，其中A为C.sub.1-4烷基烯基，R.sup.7为C.sub.1-6烷基，C.sub.3-6烯基，C.sub.3-6炔基或C.sub.2-5酰基；R.sup.6是氢原子，C.sub.1-4烷基或卤原子，以及一种制备该化合物的方法和含有该化合物作为有效成分的用于控制有害生物的化学品。

  公开号：

  US05380744A1

文献信息

• Insecticidal, acaricidal and fungicidal pyrazole phenoxyalkylamin derivatives and process for preparing the same
  申请人：UBE INDUSTRIES, LTD.

  公开号：EP0618195A1

  公开（公告）日：1994-10-05

  Disclosed are a phenoxyalkylamine compound having insecticidal, acaricidal and fungicidal activities and being represented by the formula (I): wherein R1 is C1-8 alkyl group, C3-8 cycloalkyl group, a hydrogen atom, a phenyl group, or C1-4 haloalkyl group; R2 is a halogen atom, a hydrogen atom, C1 -4 alkyl group, C1 -4 alkoxy group or a nitro group; R1 and R2 may be linked with each other and condensed to a pyrazole ring to form a saturated 4- to 8-membered ring; R3 is C1-15 alkyl group, C3-8 cycloalkyl group, a phenyl group, C1-4 haloalkyl group, C2-8 alkoxyalkyl group, C3-6 alkenyl group, a pyridyl group, a benzyl group, C3-8 alkoxycarbonylalkyl group, a pyrazole group, or C1-4 alkoxy group; R4 is C1 -4 alkyl group, a hydrogen atom or a halogen atom; R5 is C1 -2o alkyl group, a hydrogen atom, C3-6 alkenyl group, a benzyl group, a phenoxy group, a halogen atom, a cyanomethyl group or -A-O-R7 where A is C1-4 alkylene group and R7 is C1-6 alkyl group, C3-6 alkenyl group, C3-6 alkynyl group or C2-5 acyl group; and R6 is a hydrogen atom, C1 -4 alkyl group or a halogen atom, a process for preparing the same and a chemical for controlling noxious organisms containing the same as an effective ingredient.

  本发明公开了一种具有杀虫、杀螨虫和杀真菌活性的苯氧基烷基胺化合物，由式 (I) 表示： 其中 R1 是 C1-8 烷基、C3-8 环烷基、氢原子、苯基或 C1-4 卤代烷基；R2 是卤素原子、氢原子、C1-4 烷基、C1-4 烷氧基或硝基；R1 和 R2 可相互连接并缩合成吡唑环，形成饱和的 4 至 8 元环；R3是C1-15烷基、C3-8环烷基、苯基、C1-4卤代烷基、C2-8烷氧基烷基、C3-6烯基、吡啶基、苄基、C3-8烷氧基羰基、吡唑基或C1-4烷氧基；R4 是 C1-4 烷基、氢原子或卤素原子； R5 是 C1-2o 烷基、氢原子、C3-6 烯基、苄基、苯氧基、卤素原子、氰甲基或 -A-O-R7 其中 A 是 C1-4 亚烷基，R7 是 C1-6 烷基、C3-6 烯基、C3-6 炔基或 C2-5 丙烯酸基；和 R6 是氢原子、C1-4 烷基或卤素原子，以及制备上述物质的工艺和含有上述物质作为有效成分的控制有害生物的化学品。
• US5380744A
  申请人：——

  公开号：US5380744A

  公开（公告）日：1995-01-10
• Phenoxyalkylamine derivative and agricultural and horticultural chemical
  申请人：Ube Industries, Ltd.

  公开号：US05380744A1

  公开（公告）日：1995-01-10

  Disclosed are a phenoxyalkylamine compound represented by the formula (I): ##STR1## wherein R.sup.1 is C.sub.1-8 alkyl group, C.sub.3-8 cycloalkyl group, a hydrogen atom, a phenyl group, or C.sub.1-4 haloalkyl group; R.sup.2 is a halogen atom, a hydrogen atom, C.sub.1-4 alkyl group, C.sub.1-4 alkoxy group or a nitro group; R.sup.1 and R.sup.2 may be linked with each other and condensed to a pyrazole ring to form a saturated 4- to 8-membered ring; R.sup.3 is C.sub.1-15 alkyl group, C.sub.3-8 cycloalkyl group, a phenyl group, C.sub.1-4 haloalkyl group, C.sub.2-8 alkoxyalkyl group, C.sub.3-6 alkenyl group, a pyridyl group, a benzyl group, C.sub.3-8 alkoxycarbonylalkyl group, a pyrazole group, or C.sub.1-4 alkoxy group; R.sup.4 is C.sub.1-4 alkyl group, a hydrogen atom or a halogen atom; R.sup.5 is C.sub.1-20 alkyl group, a hydrogen atom, C.sub.3-6 alkenyl group, a benzyl group, a phenoxy group, a halogen atom, a cyanomethyl group or --A--O--R.sup.7 where A is C.sub.1-4 alkylene group and R.sup.7 is C.sub.1-6 alkyl group, C.sub.3-6 alkenyl group, C.sub.3-6 alkynyl group or C.sub.2-5 acyl group; and R.sup.6 is a hydrogen atom, C.sub.1-4 alkyl group or a halogen atom, a process for preparing the same and a chemical for controlling noxious organisms containing the same as an effective ingredient.

  本发明涉及一种由以下式（I）表示的苯氧基烷胺化合物：其中R.sup.1是C.sub.1-8烷基，C.sub.3-8环烷基，氢原子，苯基或C.sub.1-4卤代烷基；R.sup.2是卤原子，氢原子，C.sub.1-4烷基，C.sub.1-4烷氧基或硝基；R.sup.1和R.sup.2可以彼此连接并缩合成吡唑环以形成饱和的4-至8-成员环；R.sup.3是C.sub.1-15烷基，C.sub.3-8环烷基，苯基，C.sub.1-4卤代烷基，C.sub.2-8烷氧基烷基，C.sub.3-6烯基，吡啶基，苄基，C.sub.3-8烷氧羰基烷基，吡唑基或C.sub.1-4烷氧基；R.sup.4是C.sub.1-4烷基，氢原子或卤原子；R.sup.5是C.sub.1-20烷基，氢原子，C.sub.3-6烯基，苄基，苯氧基，卤原子，氰甲基或--A--O--R.sup.7，其中A为C.sub.1-4烷基烯基，R.sup.7为C.sub.1-6烷基，C.sub.3-6烯基，C.sub.3-6炔基或C.sub.2-5酰基；R.sup.6是氢原子，C.sub.1-4烷基或卤原子，以及一种制备该化合物的方法和含有该化合物作为有效成分的用于控制有害生物的化学品。