(Z)-N-butylpentan-2-imine | 19325-62-3

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: (Z)-N-butylpentan-2-imine
• 英文别名: N-(1-methylbutylidene)butylamine；(1-anti-Methylbutyliden)-butylamin
• CAS: 19325-62-3
• 化学式: C₉H₁₉N
• 分子量: 141.257
• InChiKey: YSWBBDGSRZJBIO-KTKRTIGZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.05
• 重原子数：
  10.0
• 可旋转键数：
  5.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  12.36
• 氢给体数：
  0.0
• 氢受体数：
  1.0

反应信息

• 作为产物：
  描述：

  N-isopropylidene-n-butylamine 、 碘乙烷 、 lithium diisopropyl amide 生成 (Z)-N-butylpentan-2-imine
  参考文献：
  名称：

  SMITH, J. K.;NEWCOMB, M.;BERGBREITER, D. E.;WILLIAMS, D. R.;MEYERS, A. I., TETRAHEDRON LETT., 1983, 24, N 34, 3559-3562

  摘要：

  DOI：

文献信息

• Zinc(II)-Catalyzed Synthesis of Propargylamines by Coupling Aldimines and Ketimines with Alkynes
  作者：Syeda Aaliya Shehzadi、Aamer Saeed、Filip Lemière、Bert U. W. Maes、Kourosch Abbaspour Tehrani

  DOI：10.1002/ejoc.201701567

  日期：2018.1.10

  Imines derived from unactivated aldehydes or ketones and primary amines or α‐amino acid esters have been shown to undergo a ZnII‐catalyzed reaction with a variety of terminal alkynes to give secondary propargylamines that have tri‐ and tetrasubstituted α‐carbon atoms (from aldimines and ketimines, respectively).

  已证明衍生自未活化醛或酮，伯胺或α-氨基酸酯的亚胺与各种末端炔烃进行Zn II催化反应，生成具有三或四取代α-碳原子的仲炔丙胺（来自醛亚胺和ketimines）。
• Process for the preparation of organic compounds with manganese cataylsts or the like
  申请人：——

  公开号：US20020165416A1

  公开（公告）日：2002-11-07

  A process of the present invention produces an organic compound by allowing a compound containing an electron attractive group of following Formula (1): 1 wherein Y is an electron attractive group; and R b and R c are each a hydrogen atom or an organic group, where Y, R b and R c may respectively be combined with each other to form a ring with an adjacent carbon atom, to react with a compound containing an unsaturated carbon-carbon bond of following Formula (2) or 2 wherein R d , R e , R f , R g , R i and R j are each a hydrogen atom or an organic group, where R d , R e , R f and R g may respectively be combined to form a ring with one or two adjacent carbon atoms, and R i and R j may be combined to form a ring with adjacent two carbon atoms, in the presence of oxygen and a catalytic compound of a Group 5, 6, 7, 8 or 9 element of the Periodic Table of Elements to yield a compound of following Formula (3) or (8): 3 wherein Z is a hydrogen atom or a hydroxyl group; and Y, R b , R c , R d , R e , R f , R g , R i and R j have the same meanings as defined above. This process can efficiently produce a compound having an alkyl group or alkenyl group bonded at the alpha position of an electron attractive group, or a derivative thereof, by catalytic radical addition reaction.

  本发明的一种过程通过允许含有下式（1）中的电子亲合基团的化合物与含有下式（2）的不饱和碳-碳键的化合物在氧气和周期表元素的5、6、7、8或9族的催化化合物存在下反应，产生下式（3）或（8）的化合物： 其中Y是一个电子亲合基团；Rb和Rc分别是氢原子或有机基团，其中Y、Rb和Rc可以分别结合在一起形成与相邻碳原子的环；Rd、Re、Rf、Rg、Ri和Rj分别是氢原子或有机基团，其中Rd、Re、Rf和Rg可以分别结合在一起形成与一个或两个相邻碳原子的环，而Ri和Rj可以结合在一起形成与相邻两个碳原子的环。这个过程可以通过催化自由基加成反应高效地产生在电子亲合基团的α位结合有烷基或烯基基团的化合物，或其衍生物。
• Process for producing organic compounds using nitrites
  申请人：——

  公开号：US20030171618A1

  公开（公告）日：2003-09-11

  A process produces an organic compound by allowing (A) a compound capable of generating a free radical to react with (B) at least one of esters and salts of nitrous acid in the presence of a nitrogen-containing cyclic compound constitutively having a skeleton represented by following Formula (i) in its ring: 1 wherein X is an oxygen atom or an —OR group, and wherein R is a hydrogen atom or a hydroxyl-protecting group. Examples of the nitrogen-containing cyclic compound are cyclic imide compounds having a cyclic imide skeleton represented by following Formula (I): 2 wherein n is 0 or 1; X is an oxygen atom or an —OR group, and wherein R is a hydrogen atom or a hydroxyl-protecting group.

  该过程通过允许（A）具有产生自由基的化合物与（B）硝酸酯和盐中至少一种在氮含环腺嘌呤化合物的存在下反应来产生有机化合物，该氮含环腺嘌呤化合物在其环中具有以下式（i）所表示的骨架：1其中X为氧原子或-OR基团，R为氢原子或羟基保护基团。氮含环腺嘌呤化合物的示例是具有以下式（I）所表示的环状咪唑酰衍生物骨架的环状咪唑化合物：2其中n为0或1；X为氧原子或-OR基团，R为氢原子或羟基保护基团。
• Process for producing aziridine compound
  申请人：Daicel Chemical Industries, Ltd.

  公开号：EP1038866A1

  公开（公告）日：2000-09-27

  In the presence of an iridium compound, an imine of the following formula (1): wherein R1, R2 and R3 are each, identical to or different from one another, a hydrogen atom or a non-reactive organic group, where R1 and R2 may be combined to form a ring together with the adjacent carbon atom, is reacted with a diazoacetic acid derivative of the following formula (2):         N2CHR4     (2) wherein R4 is a cyano group, an alkoxycarbonyl group, a carbamoyl group or the like, to yield an aziridine compound of the following formula (5): wherein R1, R2, R3 and R4 have the same meanings as defined above. The process can easily and efficiently produce aziridine compounds.

  在铱化合物存在的情况下，下式(1)的亚胺： 其中 R1、R2 和 R3 各自为相同或不同的氢原子或非反应性有机基团，其中 R1 和 R2 可与相邻碳原子结合形成一个环，该亚胺与下式（2）的重氮乙酸衍生物反应： N2CHR4 (2) 其中 R4 为氰基、烷氧羰基、氨基甲酰基或类似基团，生成下式（5）的氮丙啶化合物： 其中 R1、R2、R3 和 R4 的含义与上述定义相同。该工艺可以方便、高效地生产氮丙啶化合物。
• Process for producing oximes using nitirites
  申请人：Daicel Chemical Industries, Ltd.

  公开号：EP1342715A2

  公开（公告）日：2003-09-10

  A process produces an organic compound by allowing (A) a compound capable of generating a free radical to react with (B) at least one of esters and salts of nitrous acid in the presence of a nitrogen-containing cyclic compound constitutively having a skeleton represented by following Formula (i) in its ring: wherein X is an oxygen atom or an -OR group, and wherein R is a hydrogen atom or a hydroxyl-protecting group. Examples of the nitrogen-containing cyclic compound are cyclic imide compounds having a cyclic imide skeleton represented by following Formula (I): wherein n is 0 or 1; X is an oxygen atom or an -OR group, and wherein R is a hydrogen atom or a hydroxyl-protecting group.

  一种生产有机化合物的工艺，其方法是让(A)一种能产生自由基的化合物与(B)至少一种亚硝酸酯和盐反应，反应物存在于一种含氮环状化合物中，该环状化合物在其环中具有下式(i)所代表的骨架： 其中 X 为氧原子或-OR 基团，R 为氢原子或羟基保护基团。含氮环状化合物的例子是环状亚胺化合物，其环状亚胺骨架由下式（I）表示： 其中 n 为 0 或 1；X 为氧原子或-OR 基团，R 为氢原子或羟基保护基团。