1,4-Diphenyl-2,3-benzoxazin-1-ol

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并恶嗪类
• 英文名称: 1,4-Diphenyl-2,3-benzoxazin-1-ol
• 化学式: C₂₀H₁₅NO₂
• 分子量: 301.345
• InChiKey: NBCXNSFQHZFXFV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  23
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  41.8
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  1,3-二苯基异苯并呋喃 在 sodium trioxodinitrate 作用下， 以 甲醇 、 水 为溶剂， 反应 3.0h， 生成 1,4-Diphenyl-2,3-benzoxazin-1-ol
  参考文献：
  名称：

  二硝基三氧化钠（安格利盐）的环加成反应

  摘要：

  Angeli's salt undergoes a quantitative reaction with 1,3-diphenylisobenzofuran in a methanol/water solution at room temperature to give a product (1) explicable by an initial [4+2] cycloaddition reaction. Under the same conditions, Angeli's salt reacts with 1-naphthaldehyde to give 1-naphthoic acid in good yield. This reaction can also be explained by an initial [2+2] cycloaddition to give a hydroxamic acid, which is then hydrolyzed to the carboxylic acid. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(99)00962-4

文献信息

• Cycloaddition reactions of sodium dinitroxytrioxide (Angeli's salt)
  作者：Lokman Torun、Taj Mohammad、Harry Morrison

  DOI：10.1016/s0040-4039(99)00962-4

  日期：1999.7

  Angeli's salt undergoes a quantitative reaction with 1,3-diphenylisobenzofuran in a methanol/water solution at room temperature to give a product (1) explicable by an initial [4+2] cycloaddition reaction. Under the same conditions, Angeli's salt reacts with 1-naphthaldehyde to give 1-naphthoic acid in good yield. This reaction can also be explained by an initial [2+2] cycloaddition to give a hydroxamic acid, which is then hydrolyzed to the carboxylic acid. (C) 1999 Elsevier Science Ltd. All rights reserved.