6a,7,8,10a-四氢-1-羟基-6,6-二甲基-3-戊基-6H-二苯并[b,d]吡喃-9-甲醇 | 26108-40-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 中文名称: 6a,7,8,10a-四氢-1-羟基-6,6-二甲基-3-戊基-6H-二苯并[b,d]吡喃-9-甲醇
• 英文名称: 11-Hydroxy-D9-THC
• 英文别名: 11-hydroxy-Δ⁹-tetrahydrocannabinol；11-OH-Δ⁹-tetrahydrocannabinol；11-OH-THC；11-hydroxy-tetrahydrocannabinol；6a,7,8,10a-Tetrahydro-1-hydroxy-6,6-dimethyl-3-pentyl-6H-dibenzo(b,d)pyran-9-methanol；9-(hydroxymethyl)-6,6-dimethyl-3-pentyl-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-ol
• CAS: 26108-40-7
• 化学式: C₂₁H₃₀O₃
• 分子量: 330.467
• InChiKey: YCBKSSAWEUDACY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  24
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  49.7
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  三甲基氯硅烷 、 6a,7,8,10a-四氢-1-羟基-6,6-二甲基-3-戊基-6H-二苯并[b,d]吡喃-9-甲醇 、 α-溴-2,3,4,5,6-五氟甲基苯酸酯 生成
  参考文献：
  名称：

  固相支持试剂测定血浆中的大麻素。

  摘要：

  DOI：

  10.1021/ac00295a012

文献信息

• CANNABIS INFUSED BEVERAGES
  申请人：Lost County, Inc.

  公开号：EP3482640A1

  公开（公告）日：2019-05-15

  Cannabis infused beverages, and a method and system for preparing the cannabis infused beverages. A dealcoholized cannabis infused beverage may include a dealcoholized beverage and a phytocannabinoid preparation. An entourage preparation including terpenoids may be included in the cannabis infused beverage. The entourage preparation may include a cannabis hydrosol. A non-alcoholic cannabis infused beverage may include a phytocannabinoid preparation and a cannabis hydrosol. The non-alcoholic cannabis infused beverage may be prepared from water, fruit juice, coffee, tea, or other base beverages.

  大麻浸泡饮料以及制备大麻浸泡饮料的方法和系统。脱醇大麻浸泡饮料可包括脱醇饮料和植物大麻素制剂。大麻浸泡饮料中可包括一种包括萜类化合物的辅助制剂。随附制剂可包括大麻水溶液。非酒精大麻浸泡饮料可包括植物大麻素制剂和大麻水醇。非酒精大麻浸泡饮料可以用水、果汁、咖啡、茶或其他基础饮料制备。
• Compound and method for treatment of diseases and disorders
  申请人：Kariman Alexander

  公开号：US10307392B2

  公开（公告）日：2019-06-04

  The disclosed invention generally relates to treatment and/or prevention of symptoms associated with cannabinoid responsive diseases and disorders in subjects in need thereof, as well as the method of administering therapeutically-effective amount of a pharmaceutical compound containing cannabinoids. The disclosed invention further relates to pharmaceutical compounds for treating and/or preventing symptoms associated with said diseases and disorders.

  所公开的发明一般涉及治疗和/或预防有需要的受试者中与大麻素反应性疾病和紊乱相关的症状，以及施用治疗有效量的含大麻素的药用化合物的方法。本发明还涉及用于治疗和/或预防上述疾病和紊乱相关症状的药物化合物。
• Cannabis-based bioactive formulations and methods for use thereof
  申请人：Segreti Louis M.

  公开号：US10517848B2

  公开（公告）日：2019-12-31

  Disclosed are compositions and methods for mitigating a tolerance effect from ingestion of cannabis-based medicines in human subjects, for example, subjects having an increased risk of unresponsiveness to one or more therapeutic agents such as, for example, antidepressants and antianxiety drugs. In some methods, the human subjects have been previously treated with one or more therapeutic agents such as, for example, antidepressants and antianxiety drugs, and have developed at least partial tolerance to the one or more therapeutic agents.

  所公开的是用于减轻人类受试者（例如，对一种或多种治疗剂如抗抑郁药和抗焦虑药无反应的风险增加的受试者）摄入大麻基药物产生的耐受效应的组合物和方法。在某些方法中，人体受试者以前曾接受过一种或多种治疗剂的治疗，例如抗抑郁药和抗焦虑药，并对一种或多种治疗剂产生了至少部分耐受性。
• Breeding, production, processing and use of specialty cannabis
  申请人：Biotech Institute LLC

  公开号：US10582676B2

  公开（公告）日：2020-03-10

  The invention provides compositions and methods for the breeding, production, processing and use of specialty cannabis.

  本发明为特种大麻的培育、生产、加工和使用提供了组合物和方法。
• Dual swab fluid sample collection for split sample testing and fingerprint identification device
  申请人：Guirguis Raouf A

  公开号：US10564155B2

  公开（公告）日：2020-02-18

  An apparatus for testing a fluid sample including a sample receiving member having an opening for receiving a fluid sample, wherein the sample receiving member comprises at least a first and second sample collection chambers, a sample retention member, in fluid communication with the first sample collection chamber, to retain a portion of the fluid sample, and at least one test strip, in fluid communication with the second collection chamber, to indicate the presence or absence of at least one analyte in the fluid sample, wherein the first collection chamber is not in fluid communication with the second collection chamber.

  一种用于检测流体样品的仪器，包括一个样品接收部件，该部件具有一个用于接收流体样品的开口，其中样品接收部件包括至少一个第一和第二样品收集室、一个与第一样品收集室流体相通的用于保留部分流体样品的样品保留部件，以及至少一个与第二收集室流体相通的用于指示流体样品中是否存在至少一种分析物的测试条，其中第一收集室不与第二收集室流体相通。