4-异丙氧基-2-甲基-苯酚 | 1243374-05-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 中文名称: 4-异丙氧基-2-甲基-苯酚
• 英文名称: 4-isopropoxy-2-methyl-phenol
• 英文别名: 4-i-propoxy-2-methylphenol；4-Isopropoxy-2-methylphenol；2-methyl-4-propan-2-yloxyphenol
• CAS: 1243374-05-1
• 化学式: C₁₀H₁₄O₂
• 分子量: 166.22
• InChiKey: XEDRITKMMGBNOP-UHFFFAOYSA-N

物化性质

• 沸点：
  271.8±20.0 °C(Predicted)
• 密度：
  1.029±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  甲基苯醌 、 异丙醇 在 Amberlyst-15 作用下， 反应 6.0h， 生成 4-异丙氧基-2-甲基-苯酚 、 4-isopropoxy-3-methyl-phenol
  参考文献：
  名称：

  Facile conversion of para-benzoquinones to para-alkoxyphenols with primary/secondary alcohols and amberlyst-15: a process showing novel reducing property of such alcohols

  摘要：

  A new efficient methodology has been developed for the synthesis of para-alkoxyphenols, an important group of anti-melanoma compounds, by heating alcoholic solutions of para-benzoquinones in the presence of amberlyst-15. The most notable feature here is the behaviour of the used primary or secondary alcohol as an effective reducing agent. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.10.119

文献信息

• [EN] INHIBITORS OF ACETYL-COA CARBOXYLASE<br/>[FR] INHIBITEURS DE L'ACÉTYL-COA CARBOXYLASE
  申请人：FOREST LAB HOLDINGS LTD

  公开号：WO2010127208A1

  公开（公告）日：2010-11-04

  The present invention relates to compounds that act as acetyl-CoA carboxylase (ACC) inhibitors. The invention also relates to methods of preparing the compounds, compositions containing the compounds, and to methods of treatment using the compounds.

  本发明涉及作为乙酰辅酶A羧化酶（ACC）抑制剂的化合物。该发明还涉及制备这些化合物的方法、含有这些化合物的组合物，以及使用这些化合物进行治疗的方法。
• ULTRAVIOLET CURABLE LIQUID COMPOSITION, ULTRAVIOLET CURING INKJET INK, ULTRAVIOLET CURING WET ELECTROPHOTOGRAPHIC LIQUID DEVELOPER, ULTRAVIOLET CURING ELECTROSTATIC INKJET INK, AND IMAGE FORMING METHOD USING THEREOF
  申请人：Canon Kabushiki Kaisha

  公开号：EP3242897A1

  公开（公告）日：2017-11-15
• [EN] THIAZOLE COMPOUNDS USEFUL AS ACETYL-COA CARBOXYLASE (ACC) INHIBITORS<br/>[FR] COMPOSÉS THIAZOLES UTILES COMME INHIBITEURS DE L'ACÉTYL-CoA CARBOXYLASE (ACC)
  申请人：JUBILANT BIOSYS LTD

  公开号：WO2012090219A2

  公开（公告）日：2012-07-05

  The present invention provides thiazole compounds of Formula I or its pharmaceutically acceptable salts, prodrugs, solvates, N-oxide thereof; solvates of pharmaceutically acceptable salts and N-oxides; pharmaceutically acceptable salts of N-oxides, or prodrugs; or combination or mixtures thereof; (I) The present invention further provides a method for preventing or treating a condition that responds to an Acetyl-CoA Carboxylase (ACC) inhibitor by using compounds of formula (I) or ), its pharmaceutically acceptable salts, prodrugs, solvates, N-oxide thereof; solvates of pharmaceutically acceptable salts and N-oxides; pharmaceutically acceptable salts of N-oxides, or prodrugs; or combination or mixtures thereof.
• [EN] ULTRAVIOLET CURABLE LIQUID COMPOSITION, ULTRAVIOLET CURING INKJET INK, ULTRAVIOLET CURING WET ELECTROPHOTOGRAPHIC LIQUID DEVELOPER, ULTRAVIOLET CURING ELECTROSTATIC INKJET INK, AND IMAGE FORMING METHOD USING THEREOF<br/>[FR] COMPOSITION LIQUIDE DURCISSABLE AUX ULTRAVIOLETS, ENCRE POUR IMPRESSION À JET D'ENCRE DURCISSANT AUX ULTRAVIOLETS, RÉVÉLATEUR LIQUIDE ÉLECTROPHOTOGRAPHIQUE PAR VOIE HUMIDE DURCISSANT AUX ULTRAVIOLETS, ENCRE À JET D'ENCRE ÉLECTROSTATIQUE DURCISSANT AUX ULTRAVIOLETS, ET PROCÉDÉ DE FORMATION D'IMAGE LES UTILISANT
  申请人：CANON KK

  公开号：WO2016111380A1

  公开（公告）日：2016-07-14

  An object of the present invention is to provide an ultraviolet curing liquid composition having high sensitivity, excellent storage stability, low viscosity, and excellent fixability after ultraviolet curing. The ultraviolet curable liquid composition of the present invention is an ultraviolet curable liquid composition containing a cationically polymerizable liquid monomer, a photopolymerization initiator and a photopolymerization sensitizer, wherein the cationically polymerizable liquid monomer is a vinyl ether compound, the photopolymerization initiator includes a compound represented by general formula (1), and the photopolymerization sensitizer includes, (A) at least one compound selected from the group consisting of a compound represented by general formula (2) and a compound represented by general formula (3), and (B) at least one compound selected from the group consisting of a compound represented by general formula (4) and a compound represented by general formula (5).
• Facile conversion of para-benzoquinones to para-alkoxyphenols with primary/secondary alcohols and amberlyst-15: a process showing novel reducing property of such alcohols
  作者：Rina Mondal、Chayan Guha、Asok K. Mallik

  DOI：10.1016/j.tetlet.2013.10.119

  日期：2014.1

  A new efficient methodology has been developed for the synthesis of para-alkoxyphenols, an important group of anti-melanoma compounds, by heating alcoholic solutions of para-benzoquinones in the presence of amberlyst-15. The most notable feature here is the behaviour of the used primary or secondary alcohol as an effective reducing agent. (C) 2013 Elsevier Ltd. All rights reserved.