2-ethylamino-butan-1-ol | 20636-06-0

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 2-ethylamino-butan-1-ol
• 英文别名: 2-Aethylamino-butan-1-ol；(+/-)-2-Ethylamino-butanol-(1)；2-(Ethylamino)butan-1-ol
• CAS: 20636-06-0
• 化学式: C₆H₁₅NO
• mdl: MFCD11163822
• 分子量: 117.191
• InChiKey: BMTAVLCPOPFWKR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  8
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  32.3
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-ethylamino-butan-1-ol 、 N-(2-氯乙基)丙烷-2-胺盐酸盐 生成 (+/-)-N-Ethyl-N-(1-hydroxymethyl-propyl)-N'-isopropyl-ethylendiamin
  参考文献：
  名称：

  Antituberculous Agents. III. (+)-2,2 -(Ethylenediimino)-di-1-butanol^1,2 and Some Analogs

  摘要：

  DOI：

  10.1021/jm01239a018
• 作为产物：
  描述：

  N-acetyl-N-(1-hydroxybutan-2-yl)acetamide 在 lithium aluminium tetrahydride 作用下， 生成 2-ethylamino-butan-1-ol
  参考文献：
  名称：

  Antituberculous Agents. III. (+)-2,2 -(Ethylenediimino)-di-1-butanol^1,2 and Some Analogs

  摘要：

  DOI：

  10.1021/jm01239a018

文献信息

• Proton magnetic resonance studies of compounds with bridgehead nitrogen atoms—XXVI
  作者：T.A. Crabb、M.J. Hall、R.O. Williams

  DOI：10.1016/s0040-4020(01)93494-5

  日期：1973.1

  3′-disubstituted, and 3,5-disubstitted perhydro-7a-methyloxazolo[3,4-c]oxazoles has been synthesised. Some indication of the predominant conformations of these systems and of the related perhydro-imidazo[1,5-c]thiazoles is obtainable from the magnitude of the geminal coupling constants of the methylene group protons situated between the heteroatoms.

  已经合成了一系列的3-单取代的，3,3'-二取代的和3,5-二取代的全氢-7a-甲基恶唑并[3,4- c ]恶唑。这些体系和相关的全氢咪唑并[1，5- c ]噻唑的主要构型的某些迹象可从位于杂原子之间的亚甲基质子的双键偶合常数的大小获得。
• METHOD FOR FRACTIONATING STEREOISOMERIC COMPOUNDS
  申请人：Jakel Christoph

  公开号：US20090030235A1

  公开（公告）日：2009-01-29

  The present invention relates to a method for fractionating stereoisomeric compounds which have at least one alcohol and/or amino group.

  本发明涉及一种用于分离具有至少一种醇和/或氨基团的立体异构化合物的方法。
• 10a-Azalide Compound
  申请人：Sugimoto Tomohiro

  公开号：US20090281292A1

  公开（公告）日：2009-11-12

  [Object]: To provide a compound having a novel structure effective against Hemophilus influenzae and erythromycin resistant bacteria (for example, resistant pneumococci and streptococci) as well as against conventional erythromycin sensitive bacteria. [Solution]: A novel 10a-azalide compound represented by the formula (I), a pharmaceutically acceptable salt thereof or a solvate thereof, or an intermediate for the preparation of the same. The compound of the present invention has superior antibacterial activity against Hemophilus influenzae , erythromycin resistant pneumococci and the like, and therefore, the compound can be used as a therapeutic agent of infectious diseases.

  【目标】提供一种具有新结构的化合物，对流感嗜血杆菌和红霉素耐药菌（例如耐药肺炎球菌和链球菌）以及传统的红霉素敏感菌具有有效作用。 【解决方案】本发明提供了一种新型10a-氮杂环十六元化合物，其化学式为（I），其药学上可接受的盐或其溶剂化物，或其制备的中间体。该化合物对流感嗜血杆菌、红霉素耐药性肺炎球菌等具有卓越的抗菌活性，因此可以作为治疗传染病的药物。
• Dynamic multi-purpose composition for the removal of photoresists and method for its use
  申请人：Dynaloy, LLC

  公开号：EP2657770A1

  公开（公告）日：2013-10-30

  Improved dry stripper solutions for removing one, two or more photoresist layers from substrates are provided. The stripper solutions comprise dimethyl sulfoxide, a quaternary ammonium hydroxide, and an alkanolamine, an optional secondary solvent and less than about 3 wt.% water and/or a dryness coefficient of at least about 1. Methods for the preparation and use of the improved dry stripping solutions are additionally provided.

  提供了用于从基底上去除一层、两层或多层光阻的改进型干法剥离剂溶液。这些剥离剂溶液包括二甲基亚砜、季铵氢氧化物、烷醇胺、任选的辅助溶剂和小于约 3 重量百分比的水和/或干燥系数至少约为 1 的溶液，此外还提供了制备和使用改进型干法剥离溶液的方法。
• Dynamic multi-purpose composition for the removal of photoresists
  申请人：Dynaloy, LLC

  公开号：EP2657771A1

  公开（公告）日：2013-10-30

  Improved dry stripper solutions for removing one, two or more photoresist layers from substrates are provided. The stripper solutions comprise dimethyl sulfoxide, a quaternary ammonium hydroxide, and an alkanolamine, an optional secondary solvent and less than about 3 wt.% water and/or a dryness coefficient of at least about 1. Methods for the preparation and use of the improved dry stripping solutions are additionally provided.

  提供了用于从基底上去除一层、两层或多层光阻的改进型干法剥离剂溶液。这些剥离剂溶液包括二甲基亚砜、季铵氢氧化物、烷醇胺、任选的辅助溶剂和小于约 3 重量百分比的水和/或干燥系数至少约为 1 的溶液，此外还提供了制备和使用改进型干法剥离溶液的方法。

表征谱图