烯丙基丁基碳酸酯 | 16308-66-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机碳酸及其衍生物
• 中文名称: 烯丙基丁基碳酸酯
• 英文名称: allyl butyl carbonate
• 英文别名: Carbonic acid, allyl butyl ester；butyl prop-2-enyl carbonate
• CAS: 16308-66-0
• 化学式: C₈H₁₄O₃
• 分子量: 158.197
• InChiKey: DUCQZMNLGAVYKS-UHFFFAOYSA-N

物化性质

• 沸点：
  179.9±19.0 °C(Predicted)
• 密度：
  0.955±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  11
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  烯丙基丁基碳酸酯 在 C₃₀H₂₁O₆PS₂^(2-)*2Na⁽¹⁺⁾ 、 水 、 palladium diacetate 、 二乙胺 作用下， 生成 正丁醇
  参考文献：
  名称：

  新型易制备的两亲性膦在有机金属水溶液中的性质和催化活性

  摘要：

  三苯膦（PPh 3）和环己基（苯基）膦的单和二磺化两亲型很容易从商业试剂和硫酸中合成。通过表面张力，等温滴定量热法，核磁共振和低温透射电子显微镜研究了这些膦在溶液中的行为。根据磺化程度证明了两种不同的超分子组装。单磺化的膦形成了组织良好的胶束状聚集体，而二磺化的膦则形成了异质且无组织的囊状组装体。在两相，钯催化的烯丙基烷基碳酸酯的水相双相裂解中，评估了这些两亲膦的效率。

  DOI：

  10.1002/adsc.201000014
• 作为产物：
  描述：

  烯丙醇 、 正溴丁烷 、 1,8-二氮杂双环[5.4.0]十一碳-7-烯 以56%的产率得到
  参考文献：
  名称：

  HORI YUJI; NAGANO YOSHIAKI; NAKAO JUNJI; FUKUHARA TAKASHI; TANIGUCHI HIRO+, CHEM. EXPRESS, 1,(1986) N 4, 224-227

  摘要：

  DOI：

文献信息

• Activated Carbon as a Mass-Transfer Additive in Aqueous Organometallic Catalysis
  作者：Nicolas Kania、Bastien Léger、Sophie Fourmentin、Eric Monflier、Anne Ponchel

  DOI：10.1002/chem.201000085

  日期：——

  Carbon, on active duty: The addition of activated carbon into the reaction medium appears to be a simple and efficient method to solve mass‐transfer limitations in aqueous organometallic catalysis (see figure).

  活性碳：将活性炭添加到反应介质中似乎是解决水性有机金属催化中传质限制的一种简单有效的方法（见图）。
• NOVEL ACRYLATES, NOVEL ALLYL ETHERS, NOVEL ALLYL CARBONATES, ACRYLATE POLYMERS, ALLYL ETHER POLYMERS, ALLYL CARBONATE POLYMERS, AND SOLID POLYELECTROLYTES
  申请人：MITSUI PETROCHEMICAL INDUSTRIES, LTD.

  公开号：EP0787749A1

  公开（公告）日：1997-08-06

  The novel acrylic ester, allyl ether and allyl carbonate of the present invention are characterized by having the structures represented by the following general formulae (I) to (IV): The above acrylic ester, allyl ether and allyl carbonate are used as a starting monomer which forms a polymer matrix for use in a polymeric solid electrolyte. The novel polymer of the present invention comprises structural units derived from at least one compound selected from a group of the compounds represented by the above general formulae (I) to (IV). The polymeric solid electrolyte comprising the above novel polymer as a polymer matrix exhibits high ionic conductivity and is chemically stable. The polymeric solid electrolyte comprising the above novel polymer as a matrix exhibits high ionic conductivity and is electrochemically stable, so that it can be used in, for example, an electrochemical element such as a primary battery, a secondary battery, a capacitor or an electrochromic display and a medical actuator.

  本发明的新型丙烯酸酯、烯丙基醚和碳酸烯丙基酯的特点是具有以下通式 (I) 至 (IV) 所代表的结构： 上述丙烯酸酯、烯丙基醚和碳酸烯丙基酯用作起始单体，形成聚合物基体，用于聚合固体电解质。 本发明的新型聚合物由至少一种从上述通式（I）至（IV）所代表的化合物组中选出的化合物衍生的结构单元组成。由上述新型聚合物作为聚合物基质的聚合物固体电解质具有高离子电导率和化学稳定性。 以上述新型聚合物为基质的聚合物固体电解质具有高离子导电性和电化学稳定性，因此可用于电化学元件，例如一次电池、二次电池、电容器或电致变色显示器和医疗致动器。
• Allylic carbonates. Efficient allylating agents of carbonucleophiles in palladium-catalyzed reactions under neutral conditions
  作者：Jiro Tsuji、Isao Shimizu、Ichiro Minami、Yukihiro Ohashi、Teruo Sugiura、Kazuhiko Takahashi

  DOI：10.1021/jo00209a032

  日期：1985.5
• Lacroix, Thibaut; Bricout, Herve; Tilloy, Sebastien, European Journal of Organic Chemistry, 1999, # 11, p. 3127 - 3129
  作者：Lacroix, Thibaut、Bricout, Herve、Tilloy, Sebastien、Monflier, Eric

  DOI：——

  日期：——
• Design, synthesis and structure-bactericidal activity relationships of novel 9-oxime ketolides and reductive epimers of acylides
  作者：Jing-Chao Tian、Xu Han、Wei Lv、Ya-Xin Li、Hui Wang、Bing-Zhi Fan、Mark Cushman、Jian-Hua Liang

  DOI：10.1016/j.bmcl.2017.02.041

  日期：2017.4

  Erythromycin was long viewed as a bacteriostatic agent. The erythromycin derivatives, 9-oxime ketolides have a species-specific bactericidal profile. Among them, the 3'-allyl version of the 9-oxime ketolide 1 (Ar = 3-quinolyl; 17a) is bactericidal against Streptococcus pneumoniae and Streptococcus pyogenes. In contrast, the 2-fluoro analogs of 1, 13a (Ar = 6-quinolyl), 13b (Ar = 3-quinolyl) and 24a (Ar = 4-isoquinolyl), show bactericidal activities against S. pneumoniae, Staphylococcus aureus and Moraxella catarrhalis, while the 2-fluoro analogs 13c (Ar = 3-aminopyridyl) and 24b (Ar = 3-carbamoylpyridyl) are only bactericidal against S. pneumoniae and Haemophilus influenzae. Reduction of the ketolides led to novel epiacylides, the 3-O-epimers of the acylides. Alteration of linker length (30b vs. 30a), 2-fluorination (33 vs. 30a) and incorporation of additional spacers at the 9-oxime or 6-OH (35, 40 vs. 30a) did not restore the epiacylides back to be as active as the acylide 31. Molecular docking suggested that epimerization at the 3 position reshapes the orientation of the 3-v-sidechain and leads to considerably weaker binding with bacterial ribosomes. (C) 2017 Elsevier Ltd. All rights reserved.