4-[2-[4-(二甲氨基)苯基]乙基]-N,N-二甲基苯胺 | 793-08-8

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 中文名称: 4-[2-[4-(二甲氨基)苯基]乙基]-N,N-二甲基苯胺
• 英文名称: N,N,N',N'-tetramethyl-α,α'-bi-p-toluidine
• 英文别名: 1,2-bisethane；4,4'-bis(dimethylaminobenzyl)；1,2-bis(4-N,N-dimethylaminophenyl)ethane；4,4'-(ethane-1,2-diyl)bis(N,N-dimethylaniline)；α.β-Bis-(4-dimethylamino-phenyl)-aethan；tetra-N-methyl-bibenzyl-4,4'-diyldiamine；4.4'-Bis-dimethylamino-bibenzyl；4.4'-Bis-dimethylamino-dibenzyl；Benzenamine, 4,4'-(1,2-ethanediyl)bis[N,N-dimethyl-；4-[2-[4-(dimethylamino)phenyl]ethyl]-N,N-dimethylaniline
• CAS: 793-08-8
• 化学式: C₁₈H₂₄N₂
• 分子量: 268.402
• InChiKey: KTSAZBIMVPAQNB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  20
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  6.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4-[2-[4-(二甲氨基)苯基]乙基]-N,N-二甲基苯胺 在 sodium hydroxide 、 silver(I) chloride 作用下， 生成 hexa-N-methyl-bibenzyl-4,4'-diyl-di-ammonium; dichloride
  参考文献：
  名称：

  US2760978

  摘要：

  公开号：
• 作为产物：
  描述：

  4,4'-bis(dimethylamino)dibenzyl disulfide 在 铜 作用下， 生成 4-[2-[4-(二甲氨基)苯基]乙基]-N,N-二甲基苯胺
  参考文献：
  名称：

  Carbonatite metasomatized peridotite xenoliths from southern Patagonia: implications for lithospheric processes and Neogene plateau magmatism

  摘要：

  The mineral chemistry, major and trace element, and Sr-Nd isotopic composition of Cr-diopside, spinel peridotite xenoliths from the Estancia Lote 17 locality in southern Patagonia document a strong carbonatitic metasomatism of the backarc continental lithosphere. The Lote 17 peridotite xenolith suite consists of hydrous spinel Iherzolite, wehrlite, and olivine websterite, and anhydrous harzburgite and Iherzolite. Two-pyroxene thermometry indicates equilibration temperatures ranging from 870 to 1015 degreesC and the lack of plagioclase or garnet suggests the xenoliths originated from between similar to 40 and 60 km depth. All of the xenoliths are LILE- and LREE-enriched, but have relatively low Sr-87/Sr-86 (0.70294 to 0.70342) and high epsilon (Nd) (+3.0 to +6.6), indicating recent trace element enrichment (similar to 25 Ma, based on the low Sr-87/Sr-86 and high Rb concentrations of phlogopite separates) in the long-term, melt-depleted Patagonian lithosphere. Lote 17 peridotite xenoliths are divided into two basic groups. Group 1 xenoliths consist of fertile peridotites that contain hydrous phases (amphibole +/- phlogopite +/- apatite). Group 1 xenoliths are further subdivided into three groups (a, b, and c) based on distinctive textures and whole-rock chemistry. Group 1 xenolith mineralogy and chemistry are consistent with a complex metasomatic history involving variable extents of recent carbonatite metasomatism (high Ca/Al, Nb/La, Zr/Hf, low Ti/Eu) that has overprinted earlier metasomatic events. Group 2 xenoliths consist of infertile, anhydrous harzburgites and record cryptic metasomatism that is attributed to CO2-rich fluids liberated from Group 1 carbonatite metasomatic reactions. Extremely variable incompatible trace element ratios and depleted Sr-Nd isotopic compositions of Lote 17 peridotite xenoliths indicate that the continental lithosphere was neither the primary source nor an enriched lithospheric contaminant for Neogene Patagonian plateau lavas. Neogene plateau magmatism associated with formation of asthenospheric slab windows may have triggered this occurrence of "intraplate-type" carbonatite metasomatism in an active continental backarc setting.

  DOI：

  10.1007/s004100000164

文献信息

• Decarboxylative Allylation of Amino Alkanoic Acids and Esters via Dual Catalysis
  作者：Simon B. Lang、Kathryn M. O’Nele、Jon A. Tunge

  DOI：10.1021/ja508317j

  日期：2014.10.1

  temperature decarboxylative allylation of recalcitrant α-amino and phenylacetic allyl esters. This operationally simple process produces CO2 as the only byproduct and provides direct access to allylated alkanes. After photochemical oxidation, the carboxylate undergoes radical decarboxylation to site-specifically generate radical intermediates which undergo allylation. A radical dual catalysis mechanism

  光氧化还原和钯催化的组合已被用于促进顽固的 α-氨基和苯乙酸烯丙酯的室温脱羧烯丙基化。这个操作简单的过程产生 CO2 作为唯一的副产品，并提供直接获取烯丙基化烷烃的途径。光化学氧化后，羧酸盐发生自由基脱羧作用，以位点特异性地生成自由基中间体，然后进行烯丙基化。提出了一种自由基双催化机制。游离苯乙酸也使用类似的反应条件进行烯丙基化。
• Towards Highly Fluorescent and Water-Soluble Perylene Dyes
  作者：Christopher Kohl、Tanja Weil、Jianqiang Qu、Klaus Müllen

  DOI：10.1002/chem.200400291

  日期：2004.11.5

  A systematic approach towards highly fluorescent, water-soluble perylene-3,4:9,10-tetracarboxylic acid diimide chromophores is presented. Water solubility was introduced first through the attachment of four hydrophilic substituents onto the bay region of the perylene dye. Positively and negatively charged groups were then applied to the chromophore, and their number and their distance from the aromatic

  提出了一种系统化的方法来制备高度荧光的水溶性per 3,4：9,10-四羧酸二酰亚胺发色团。首先通过将四个亲水性取代基连接到the染料的海湾区域上来引入水溶性。然后将带正电和带负电的基团应用于发色团，并系统地改变它们的数目和与芳香族支架的距离。为了抑制聚集，将生色团进一步分离在树突状壳内。此类结构特征的变化以及对所得光学性质的透彻研究促进了combining 3,4：9,10-四羧酸二酰亚胺的首次合成，结合了水溶性和荧光量子产率（FQYs）接近于1的特性，
• Photoinduced Charge Accumulation and Prolonged Multielectron Storage for the Separation of Light and Dark Reaction
  作者：Martin Schulz、Nina Hagmeyer、Frerk Wehmeyer、Grace Lowe、Marco Rosenkranz、Bianca Seidler、Alexey Popov、Carsten Streb、Johannes G. Vos、Benjamin Dietzek

  DOI：10.1021/jacs.0c03779

  日期：2020.9.16

  sacrificial electron donors that facilitate proton-coupled electron transfer. Repeated photochemical reduction and chemical oxida-tion reveals that the complex retained a charging capacity of 72% after four cycles. We demonstrate a chemical system that can decouple photochemical processes from the day-night cycle, which has been a barrier to realizing utilization of solar energy in photochemical processes

  太阳能的利用受到太阳涌入的间歇性的限制。我们提出了新型的无贵金属配合物，它们可以在牺牲电子供体的存在下进行光化学充电，并在其带电形式下保持稳定超过 14 小时。这使得双还原的 Cu(I) 4H-咪唑络合物在光化学充电后储存起来，并用作暗反应中的试剂，例如甲基紫精或氧气的还原。组合 UV-Vis/EPR 光谱电化学表明，通过引入促进质子耦合电子转移的牺牲电子供体，诱导了双电子还原。重复的光化学还原和化学氧化表明，该复合物在四次循环后仍保持 72% 的充电容量。
• Novel routes to 4-substituted N,N-dialkylanilines, N-alkylanilines and anilines
  作者：Alan R. Katritzky、Hengyuan Lang、Xiangfu Lan

  DOI：10.1016/s0040-4020(01)87221-5

  日期：1993.8

  N-dialkylanilines, -N-alkylanilines, -anilines and some substituted analogs obtained via lithiation are converted by lithium aluminum hydride or Grignard reagents into 4-substituted N,N-dialkylanilines, N-alkylanilines and anilines, respectively, in good yields.

  通过氢化锂铝或格氏试剂将4-（苯并三唑-1-基甲基）-N，N-二烷基苯胺，-N-烷基苯胺，-苯胺和一些通过锂化获得的取代类似物通过氢化锂铝或格氏试剂转化为4-取代的N，N-二烷基苯胺，N -烷基苯胺和苯胺分别具有良好的收率。
• Kinetics of the Decay Reactions of the <i>N</i>,<i>N-</i>Dimethyl-<i>p-</i>Toluidine Cation Radical in Acetonitrile. Acid−Base Interaction to Promote the CH₂−CH₂ Bonding
  作者：Masashi Goto、Hyun Park、Koji Otsuka、Munetaka Oyama

  DOI：10.1021/jp026073h

  日期：2002.9.1

  The decay reaction of N,N-dimethyl-p-toluidine (DMT) cation radical (DMT + ) in acetonitrile (AN) was analyzed using an electron-transfer stopped-flow (ETSF) method. In the ETSF method, DMT + is generated by mixing AN solutions of DMT and tris(p-bromophenyl)amine cation radical (TBPA + ). When DMT + was generated quantitatively without DMT via 1:1 mixing of DMT and TBPA + , it was found that DMT +

  N,N-二甲基-对甲苯胺 (DMT) 阳离子自由基 (DMT + ) 在乙腈 (AN) 中的衰变反应采用电子转移停流 (ETSF) 方法进行了分析。在 ETSF 方法中，通过混合 DMT 和三（对溴苯基）胺阳离子自由基（TBPA + ）的 AN 溶液生成 DMT + 。当通过DMT和TBPA + 1:1混合在没有DMT的情况下定量产生DMT + 时，发现DMT + 在AN中相当稳定。另一方面，当DMT/TBPA + (>1)的混合比控制下，DMT与DMT + 保持一致时，发现中性DMT促进了DMT + 的衰变反应。根据确定的速率定律，-d[DMT + ]/dt = k [DMT + ] [DMT] (k = 6.5 x 10 2 M - 1 s - 1 )，DMT + 和 DMT 之间的初始酸碱反应为澄清为速率确定步骤。通过在吡啶衍生物存在下观察 DMT + 的衰变反应也证实了酸碱相互作用