N'-[2-(2-氨基乙胺基)乙基]丙烷-1,3-二胺 | 70209-08-4

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: N'-[2-(2-氨基乙胺基)乙基]丙烷-1,3-二胺
• 英文名称: N-(2-aminoethyl)-N'-(3-aminopropyl)ethylenediamine
• 英文别名: N-3-aminopropyldiethylenetriamine；3,6-diazanonane-1,9-diamine；1,4,7,11-tetraazaundecane；2,2,3-tet；1,4,7,11-Tetraazaundecan；N1-(2-((2-Aminoethyl)amino)ethyl)propane-1,3-diamine；N'-[2-(2-aminoethylamino)ethyl]propane-1,3-diamine
• CAS: 70209-08-4
• 化学式: C₇H₂₀N₄
• 分子量: 160.263
• InChiKey: UFLJAVBLQHSCDD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.2
• 重原子数：
  11
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  76.1
• 氢给体数：
  4
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  N'-[2-(2-氨基乙胺基)乙基]丙烷-1,3-二胺 、 nickel(II) perchlorate 以 水 为溶剂， 以84%的产率得到(1,4,7,11-tetraazaundecane)nickel(II) perchlorate hydrate
  参考文献：
  名称：

  Pisarev, E. A.; Esaulenko, A. N.; Nazarova, T. M., Journal of general chemistry of the USSR, 1986, vol. 56, p. 1255 - 1255

  摘要：

  DOI：
• 作为产物：
  描述：

  3-[[2-[(2-氨基乙基)氨基]乙基]氨基]丙腈 在 乙醇 、 sodium 作用下， 以 甲醇 、 甲苯 为溶剂， 生成 N'-[2-(2-氨基乙胺基)乙基]丙烷-1,3-二胺
  参考文献：
  名称：

  氨基取代的四氮杂环烷烃与钴（III）的五齿配位。第3部分。不对称配体的合成及其顺式-氯钴（III）配合物的晶体结构

  摘要：

  非对称侧链大环9-甲基-9-硝基-1,4,7,11-四氮杂环十四烷（L 1）是通过铜（II）定向的3,6-二氮杂壬烷-1,9-二胺缩合制备的与硝基乙烷和甲醛。在水溶液中用锌还原L 1的铜（II）络合物可生成新的潜在的五齿多胺9-甲基-1,4,7,11-四氮杂环十四烷-9-胺（L 2）。水中的L 2与钴（II）离子和空气反应，然后与盐酸水溶液反应，并与活性炭平衡，仅生成顺式-[CoL 2（Cl）] [ClO 4 ] 2。，在单斜空间群P 2 1 / c中结晶，a = 12.745（5），b = 11.438（5），c = 14.414（8），β= 104.80（3）°。侧链伯胺和两个相邻的仲胺必定占据一个八面体面，氯配体顺式排列在伯胺上，仲胺采用RRSS立体化学。平均CO-N距离为1.96 0埃，钴-CL距离是2.252（1）。立体定向碱水解（k OH 9100 dm 3 mol –1 s

  DOI：

  10.1039/dt9920001649

文献信息

• BENZYLATED MANNICH BASE CURING AGENTS, COMPOSITIONS, AND METHODS
  申请人：EVONIK DEGUSSA GMBH

  公开号：US20170240691A1

  公开（公告）日：2017-08-24

  Compositions and curing agents comprising a benzylated Mannich base composition. The benzylated Mannich base composition includes a reaction product of (a) a substituted phenolic compound having at least one substituent of formula (I): wherein R 1 is each independently a linear or branched alkyl group having 1 to 4 carbon atoms, and R 2 is hydrogen, methyl, ethyl or phenyl, with (b) a benzylated polyalkylene polyamine (II): wherein R A is substituted or unsubstituted benzyl; R B is each independently R A , or a hydrogen atom, or a group selected from C 1 -C 16 linear, cyclic, and branched alkyl, alkenyl, and alkaryl groups; X, Y, and Z are independently selected from C 2 -C 10 alkylene, and cycloalkylene groups; y is an integer from 0 to 7, and z is an integer from 0 to 4; and, optionally, (c) a multifunctional amine. Amine-epoxy compositions and articles produced from these compositions are also disclosed.

  含有苄基曼尼希碱基组分的组合物和固化剂。所述苄基曼尼希碱基组分包括以下反应产物：(a)至少具有一个取代基的取代酚化合物，所述取代基的公式为(I)：其中R1各自独立地是具有1到4个碳原子的线性或支链烷基，R2是氢、甲基、乙基或苯基；(b)苄基化的聚烯烃聚醚胺(II)：其中RA是取代或未取代的苄基，RB各自独立地是RA或氢原子，或选自C1-C16线性、环状和支链烷基、烯基和烷基芳基基团；X、Y和Z各自独立地选自C2-C10烷基和环状烷基基团；y是0到7的整数，z是0到4的整数；可选地，(c)多功能胺。还公开了胺-环氧组合物和由这些组合物制成的物品。
• [EN] AMIDOAMINE AND POLYAMIDE CURING AGENTS, COMPOSITIONS, AND METHODS<br/>[FR] AGENTS, COMPOSITIONS ET PROCÉDÉS DE DURCISSEMENT D'AMIDOAMINE ET DE POLYAMIDES
  申请人：EVONIK DEGUSSA GMBH

  公开号：WO2017136333A1

  公开（公告）日：2017-08-10

  A composition including an amidoamine curing agent composition or a polyamide curing agent composition are disclosed. The composition includes the reaction products of (1) an amine component including at least one multifunctional amine of structure (I): wherein each R is independently H or CH2CH2CH2NH2; R1 is H, CH3CH2CH2N-, C1-C21 alkyl, or C1-C21 alkenyl; n is 2; and m is 1 or 2, with (2) a fatty acid or ester component selected from the group consisting of a dimer fatty acid or ester component, a monofunctional fatty acid or ester component, and combinations thereof. The amidoamine curing agent composition remains as liquid at ambient temperature.

  本发明涉及一种包括肽胺固化剂组合物或聚酰胺固化剂组合物的组成物。该组合物包括以下反应产物：(1)胺组分，包括至少一种结构为(I)的多功能胺，其中每个R独立地为H或CH2CH2CH2NH2; R1为H、CH3CH2CH2N-、C1-C21烷基或C1-C21烯基; n为2; m为1或2；(2)脂肪酸或酯组分，选自二聚脂肪酸或酯组分、单功能脂肪酸或酯组分及其组合物。该肽胺固化剂组合物在常温下仍保持液态。
• Organosilane Coating Compositions and Use Thereof
  申请人：Colreavy John

  公开号：US20100330380A1

  公开（公告）日：2010-12-30

  A sol-gel coating composition comprising a hydrolysed organosilane, an organometallic precursor and a corrosion inhibitor, wherein the corrosion inhibitor is a chelator for the organometallic precursor. The corrosion inhibitor and the organometallic precursor may form a nanoparticulate complex. The coating composition may comprise one or more additive selected from: an antimicrobial additive, a hardener, a water repelling additive, a dye, a scratch resistant additive and a flexibility enhancing additive. A process for preparing a sol gel coating composition is also described, the process comprising the steps of: hydrolysing an organosilane in the presence of a catalyst; chelating an organometallic precursor; mixing the hydrolysed silane and the chelated organometallic precursor; and hydrolysing the organosilane-organometallic precursor mixture.

  一种溶胶-凝胶涂层组合物，包括水解的有机硅烷、有机金属前体和腐蚀抑制剂，其中腐蚀抑制剂是有机金属前体的螯合剂。腐蚀抑制剂和有机金属前体可以形成纳米颗粒复合物。涂层组合物可以包括以下一种或多种添加剂：抗菌添加剂、硬化剂、防水添加剂、染料、耐刮擦添加剂和增强柔韧性添加剂。还描述了一种制备溶胶-凝胶涂层组合物的方法，包括以下步骤：在催化剂存在下水解有机硅烷；螯合有机金属前体；混合水解硅烷和螯合有机金属前体；以及水解有机硅烷-有机金属前体混合物。
• Trifunctional electrocatalysts of ternary iron copper molybdenum−Schiff bases complexes applied to Zn−air battery and alkaline water splitting
  作者：Tzu Hsuan Chiang、Yu-Si Chen

  DOI：10.1039/d3cy00228d

  日期：——

  The oxygen reduction reaction (ORR), oxygen evolution reaction (OER), and hydrogen evolution reaction (HER) performance of electrocatalysts have unique characteristics useful for Zn-air batteries and over-water splitting. In this study,...

  电催化剂的氧还原反应（ORR）、氧进化反应（OER）和氢进化反应（HER）性能具有独特的特性，可用于锌-空气电池和过水分解。在这项研究中，...
• METHOD FOR PRODUCING HYDROPHOBIC PEPTIDE
  申请人：Kaneka Corporation

  公开号：EP3199540A1

  公开（公告）日：2017-08-02

  An object of the present invention is to provide a producing method: that allows any hydrophobic peptide to be used as an object to be purified, in hydrophilizing a hydrophobic peptide, synthesized by solid-phase peptide synthesis, with a hydrophilic unit and purifying the hydrophobic peptide by HPLC, regardless of the type of the amino acid residue at the N-terminus; that allows the hydrophilic unit to be flexibly selected in accordance with the type of the hydrophobic peptide; and that is excellent in versatility. The present invention is characterized by a method for producing a purified peptide from a supported crude peptide including a support and a first peptide chain bonded to the support at a C-terminus, the method comprising: a hydrophilization step A of introducing a linker and a hydrophilic unit to an amino group of the supported crude peptide in this order stepwise or at a single step to obtain a support-free hydrophilized peptide; a support cleavage step B of cleaving a bond between the first peptide chain and the support at any stage before bonding the linker to the supported crude peptide until the hydrophilized peptide is obtained, or after a supported hydrophilized peptide is obtained; a chromatographic purification step of treating the support-free hydrophilized peptide obtained by the hydrophilization step A and the support cleavage step B, by liquid chromatography; and a linker cleavage step of cleaving a bond between the linker and the first peptide chain included in the chromatographically-purified support-free hydrophilized peptide, by chemical treatment.

  本发明的目的是提供一种生产方法：该方法可以将任何疏水性多肽作为纯化对象，在用亲水单元亲水固相多肽合成法合成的疏水性多肽时，通过高效液相色谱法纯化疏水性多肽，而不考虑N端氨基酸残基的类型；该方法可以根据疏水性多肽的类型灵活选择亲水单元；该方法具有优异的通用性。 本发明的特征在于一种从支持粗肽生产纯化肽的方法，该粗肽包括支持物和在 C 端与支持物键合的第一肽链，该方法包括： 亲水化步骤 A，按此顺序逐步或单步将连接体和亲水单元引入到支撑粗肽的氨基上，以获得无支撑的亲水化肽； 支持物裂解步骤B，在将连接物与支持物粗肽结合之前的任何阶段裂解第一肽链与支持物之间的键，直到获得亲水肽，或在获得支持物亲水肽之后； 色谱纯化步骤：用液相色谱法处理通过亲水化步骤 A 和支持物裂解步骤 B 获得的无支持物亲水化肽；以及 连接体裂解步骤，通过化学处理裂解连接体与色谱纯化的无支撑亲水肽中的第一肽链之间的键。