2,3-diphenyl-valeric acid | 5699-60-5

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 2,3-diphenyl-valeric acid
• 英文别名: 2,3-Diphenyl-valeriansaeure；α.β-Diphenyl-butan-α-carbonsaeure；α.β-Diphenyl-n-valeriansaeure；2,3-Diphenylpentanoic acid
• CAS: 5699-60-5
• 化学式: C₁₇H₁₈O₂
• 分子量: 254.329
• InChiKey: KFYZUZIIWJDNNS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  19
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2,3-diphenyl-valeric acid 生成 3-ethyl-2-phenylindanone
  参考文献：
  名称：

  MIURA, MASAHIRO;NOJIMA, MASATOMO;KUSABAYASHI, SHIGEKAZU;MCCULLOUGH, K. J., J. AMER. CHEM. SOC., 1984, 106, N 10, 2932-2936

  摘要：

  DOI：
• 作为产物：
  描述：

  (E)-2,3-二苯基丙烯腈 在 盐酸 、 乙醚 作用下， 生成 2,3-diphenyl-valeric acid
  参考文献：
  名称：

  Kohler, American Chemical Journal, 1906, vol. 35, p. 403

  摘要：

  DOI：

文献信息

• Nucleopolyhedrovirus infection in obliquebanded leafroller (Lepidoptera: Tortricidae)
  作者：I. Pronier、J. Paré、J-C Wissocq、C. Vincent

  DOI：10.4039/ent134303-3

  日期：2002.6

  A virus isolated from obliquebanded leafroller, Choristoneura rosaceana (Harris), larvae collected in an apple, Malus domestica Borkh. (Rosaceae), orchard of Saint-Joseph-du-Lac (Quebec, Canada) was studied. Microscopic studies revealed that it was a uninucleocapsid nucleopolyhedrovirus from the family Baculoviridae. Larval mortality was approximately 75% (0% mortality in control group) in larvae infected as third instars immersed in a suspension of 1.7 × 10⁸ occlusion bodies/mL. The average time for larval mortality was 23 ± 3 d after treatment. The majority (95.5%) of infected larvae died as fifth or sixth instars. Infection was observed primarily in fat body cells, and occasionally in the tracheal matrix and epidermis. Mean larval development time of infected larvae surviving to pupae was 20 ± 3 d, significantly greater than the 18 ± 3 d observed in control larvae. Adult emergence was significantly lower in pupae of treated larvae (73.6%) than in the control group (93.5%). Our work constitutes the first baseline study of naturally occurring virus of the obliquebanded leafroller.

  摘要 研究了从加拿大魁北克省圣约瑟夫-杜拉克（Saint-Joseph-du-Lac）苹果园采集的斜带卷叶蛾幼虫 Choristoneura rosaceana (Harris) 身上分离出的一种病毒。显微镜研究表明，它是一种无核噬核多角体病毒，属于杆状病毒科。三龄幼虫感染后，浸泡在 1.7 × 108 个闭锁体/毫升的悬浮液中，幼虫死亡率约为 75%（对照组死亡率为 0%）。幼虫平均死亡时间为处理后 23 ± 3 d。大多数（95.5%）受感染的幼虫在第五或第六龄时死亡。感染主要出现在脂肪体细胞中，偶尔也会出现在气管基质和表皮中。感染幼虫存活到蛹的平均发育时间为 20 ± 3 d，明显高于对照幼虫的 18 ± 3 d。经处理幼虫的蛹成虫率（73.6%）明显低于对照组（93.5%）。我们的研究是对斜带卷叶螟自然发生的病毒进行的首次基线研究。
• Peptide ligands specific to immonoglobulins
  申请人：TECNOGEN S.C.P.A.

  公开号：EP1621546A1

  公开（公告）日：2006-02-01

  A compound of formula:          (X1-X2-His-X3-CO)n-R     (I) where: X1is H or an amino acid residue of cysteine (Cys) having L or D configuration, wherein each pair of amino acid residues of Cys, optionally present as X1, can be in the form of a cystine residue owing to an -S-S- bridge formed by the -SH functions of two Cys residues, X2is an amino acid residue of tyrosine (Tyr) or of histidine (His) having L or D configuration, X3is an amino acid residue of His or Tyr having L or D configuration, provided, however, that X2 is Tyr when X3 is His and X2 is His when X3 is Tyr, Hisis an amino acid residue of histidine having L or D configuration, nis an integer of from 1 to 4, Rwhen n is 1, is OH, a residue of a single amino acid, or a peptide chain comprising from 2 to 7 amino acids,     whereas, when n is 2, 3 or 4, it is a group capable of forming a dimer, a trimer and, respectively, a tetramer.

  式的化合物： (X1-X2-His-X3-CO)n-R (I) 其中 X1 是 H 或具有 L 或 D 构型的半胱氨酸（Cys）的氨基酸残基，其中由于两个 Cys 残基的 -SH 功能形成的-S-S-桥，每对 Cys 的氨基酸残基（可选择作为 X1 存在）可以是胱氨酸残基的形式、 X2 是具有 L 或 D 构型的酪氨酸（Tyr）或组氨酸（His）的氨基酸残基、 X3 是具有 L 或 D 构型的 His 或 Tyr 的氨基酸残基，但条件是当 X3 是 His 时，X2 是 Tyr；当 X3 是 Tyr 时，X2 是 His、 His 是组氨酸的氨基酸残基，具有 L 或 D 构型、 n 是 1 至 4 的整数、 当 n 为 1 时，为 OH、单个氨基酸残基或由 2 至 7 个氨基酸组成的肽链、 而 当 n 为 2、3 或 4 时，是能够分别形成二聚体、三聚体和四聚体的基团。
• PENICILLIN-G ACYLASES
  申请人：BEHROUZIAN BEHNAZ

  公开号：US20100143968A1

  公开（公告）日：2010-06-10

  The present disclosure relates to engineered penicillin G acylase (PGA) enzymes having improved properties, polynucleotides encoding such enzymes, compositions including the enzymes, and methods of using the enzymes.
• US8247192B2
  申请人：——

  公开号：US8247192B2

  公开（公告）日：2012-08-21
• US8569013B2
  申请人：——

  公开号：US8569013B2

  公开（公告）日：2013-10-29