5-甲基-2-萘酚 | 66256-29-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 中文名称: 5-甲基-2-萘酚
• 中文别名: 5-甲基萘-2-醇
• 英文名称: 5-methyl-2-naphthol
• 英文别名: 5-Methylnaphthalen-2-ol
• CAS: 66256-29-9
• 化学式: C₁₁H₁₀O
• mdl: MFCD11114472
• 分子量: 158.2
• InChiKey: VVTMLJYBQHRIPC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

安全信息

• 海关编码：
  2907199090

反应信息

• 作为反应物：
  描述：

  5-甲基-2-萘酚 在 氨 、 sodium 作用下， 生成 5-甲基-3,4-二氢-1H-2-萘酮
  参考文献：
  名称：

  Bey,P.; Ourisson,G., Bulletin de la Societe Chimique de France, 1968, p. 2464 - 2468

  摘要：

  DOI：
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 氢氧化钾 、 水 作用下， 生成 5-甲基-2-萘酚
  参考文献：
  名称：

  EEG P300 Event-Related Markers of Hypnosis

  摘要：

  Barabasz, Barabasz, Jensen, Calvin, Trevisan, and Warner (1999) showed that, when subjects are stringently selected for hypnotizability and responses are time locked to events, robust markers of hypnotic responding emerge that reflect alterations in consciousness that correspond to subjects' subjective experiences of perceptual alteration. To further test the Barabasz et al. (1999) hypothesis, we obtained EEG visual P300 event-related potentials (ERPs) from 20 high- and low-hypnotizable subjects. The effects of positive obstructive and negative CI obliterating instructions were tested during waking and alert hypnotic conditions. High-hypnotizables showed greater ERP amplitudes in response to the negative hallucination condition and lower ERP amplitudes in response to the positive obstructive hallucination when compared to the low-hypnotizables. Contrary to socio-psychological or role play conceptualizations, the hypnotic induction resulted in specific psychophysiological responses which could not be produced by waking imagination or by the lows who were trying to mimic hypnotic responding.

  DOI：

  10.1080/00029157.2001.10403468

文献信息

• NITROGENOUS CYCLIC COMPOUND AND COLOR CHANGING FILM COMPRISING SAME
  申请人：LG CHEM, LTD.

  公开号：US20200095265A1

  公开（公告）日：2020-03-26

  The present specification relates to a compound containing nitrogen, and a color conversion film, a backlight unit, and a display device, including the same.

  本说明书涉及一种含有氮的化合物，以及包括该化合物的色转换膜、背光单元和显示设备。
• HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING SAME
  申请人：LG CHEM, LTD.

  公开号：US20180051007A1

  公开（公告）日：2018-02-22

  The present specification relates to a hetero-cyclic compound and an organic light emitting device comprising the same.

  本规范涉及一种杂环化合物和包括该化合物的有机发光器件。
• POLYCYCLIC AROMATIC COMPOUND AND ORGANOELECTROLUMINESCENT DEVICE USING THE SAME
  申请人：SFC CO., LTD.

  公开号：US20210305514A1

  公开（公告）日：2021-09-30

  Disclosed is a polycyclic aromatic compound that can be employed in an organic layer of an organic electroluminescent device. Also disclosed is a highly efficient organic electroluminescent device including the polycyclic aromatic compound. The use of the polycyclic aromatic compound significantly improves the luminous efficiency of the device.

  揭示了一种多环芳香化合物，可用于有机电致发光器件的有机层中。还揭示了包括该多环芳香化合物的高效有机电致发光器件。使用该多环芳香化合物显著提高了器件的发光效率。
• Tandem Iridium Catalysis as a General Strategy for Atroposelective Construction of Axially Chiral Styrenes
  作者：Jie Wang、Xiaotian Qi、Xiao-Long Min、Wenbin Yi、Peng Liu、Ying He

  DOI：10.1021/jacs.1c04400

  日期：2021.7.21

  Axially chiral styrenes are of great interest since they may serve as a class of novel chiral ligands in asymmetric synthesis. However, only recently have strategies been developed for their enantioselective preparation. Thus, the development of novel and efficient methodologies is highly desirable. Herein, we reported the first tandem iridium catalysis as a general strategy for the synthesis of axially

  轴向手性苯乙烯很受关注，因为它们可以在不对称合成中作为一类新的手性配体。然而，直到最近才开发出用于它们的对映选择性制备的策略。因此，非常需要开发新颖有效的方法。在此，我们报道了第一个串联铱催化作为合成轴向手性苯乙烯的通用策略，该方法通过不对称烯丙基取代异构化( AASI ) 使用碳酸肉桂酯类似物作为亲电子试剂和萘酚作为亲核试剂。在这种方法中，轴向手性苯乙烯是通过两个独立的铱催化循环产生的：铱催化的不对称烯丙基取代和原位通过由相同的铱催化剂催化的立体有择的 1,3-氢化物转移进行异构化。实验和计算研究都表明，异构化是通过铱催化的苄基 C-H 键氧化加成，然后是末端 C-H 还原消除来进行的。在中心到轴向的手性转移中，萘酚的羟基通过与 Ir(I) 中心协调在确保立体特异性方面发挥着至关重要的作用。该过程适应广泛的官能团兼容性。产物以极好的收率产生，具有极好的对映选择性，可以转化为各种轴向手性分子。
• Gold‐Catalyzed Atroposelective Synthesis of 1,1′‐Binaphthalene‐2,3′‐diols
  作者：Jianwei Zhang、Martin Simon、Christopher Golz、Manuel Alcarazo

  DOI：10.1002/anie.201915456

  日期：2020.3.27

  substituted benzyl alkynones. Essential for the achievement of high enantioselectivity during the key assembly of the naphto-3-ol unit is the use of TADDOL-derived α-cationic phosphonites as ancillary ligands. Preliminary results demonstrate that the transformation of the obtained binaphthyls into axially chiral monodentate phosphines is possible without degradation of enantiopurity.

  据报道，从一系列取代的苄基炔烃开始，具有高度的对映选择性（高达97％ee）的Au催化的Au催化1,1'-联萘-2,3'-二醇的合成。在萘-3-醇单元的关键组装过程中实现高对映选择性的关键是使用TADDOL衍生的α-阳离子亚膦酸酯作为辅助配体。初步结果表明，所获得的联萘可以转化为轴向手性单齿膦，而不会降低对映体纯度。