2,3-二甲基-6,7-二氯喹喔啉 | 52736-71-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 中文名称: 2,3-二甲基-6,7-二氯喹喔啉
• 中文别名: 2,3-二氯吡啶-4-羧酸
• 英文名称: 6,7-dichloro-2,3-dimethylquinoxaline
• CAS: 52736-71-7
• 化学式: C₁₀H₈Cl₂N₂
• mdl: MFCD00107126
• 分子量: 227.093
• InChiKey: XUIDIVNOOAVBBF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  14
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  25.8
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2933990090

反应信息

• 作为产物：
  描述：

  4,5-二氯-2-硝基苯胺 、 2,3-丁二醇 在 sodium hydroxide 作用下， 以 甲苯 为溶剂， 反应 3.0h， 以63%的产率得到2,3-二甲基-6,7-二氯喹喔啉
  参考文献：
  名称：

  NaOH-Mediated Direct Synthesis of Quinoxalines from o-Nitroanilines and Alcohols via a Hydrogen-Transfer Strategy

  摘要：

  A NaOH-mediated sustainable synthesis of functionalized quinoxalines is disclosed via redox condensation of o-nitroamines with diols and α-hydroxy ketones. Under optimized conditions, various o-nitroamines and alcohols are well tolerated to generate the desired products in 44-99% yields without transition metals and external redox additives.

  DOI：

  10.1021/acs.joc.0c02453

文献信息

• PROCESS FOR PRODUCING OPTICALLY ACTIVE AMINE
  申请人：TAKASAGO INTERNATIONAL CORPORATION

  公开号：US20150210657A1

  公开（公告）日：2015-07-30

  A process for producing an optically active amine compound, characterized by asymmetrically hydrogenating a prochiral carbon-nitrogen double bond in the presence of a ruthenium complex represented by general formula (1) or (2) (wherein P represents an optically active diphosphine, X represents an anionic group, and Ar represents an optionally substituted arylene group).

  一种制备光学活性胺化合物的方法，其特征在于在存在由通用式（1）或（2）表示的钌配合物的情况下，对一个丙半胱氨基双键进行不对称氢化（其中P代表光学活性二膦，X代表阴离子基团，Ar代表可选择取代的芳基基团）。
• Green and Efficient Synthesis of Quinoxaline Derivatives via Ceric Ammonium Nitrate Promoted and in Situ Aerobic Oxidation of .ALPHA.-Hydroxy Ketones and .ALPHA.-Keto Oximes in Aqueous Media
  作者：Ahmad Shaabani、Ali Maleki

  DOI：10.1248/cpb.56.79

  日期：——

  The direct conversion of alpha-hydroxy ketones and alpha-keto oximes into quinoxaline derivatives in the presence of a catalytic amount of ceric ammonium nitrate via metal-catalyzed aerobic oxidation followed by in situ trapping with aromatic 1,2-diamines in water as a green and efficient reaction media, is reported.

  在催化量的硝酸铈铵存在下，通过金属催化的需氧氧化，将α-羟基酮和α-酮肟直接转化为喹喔啉衍生物，然后在水中将芳族1,2-二胺原位捕集为绿色高效反应介质的报道。
• Quinoxalino-fused sultines and their application in Diels–Alder reactions
  作者：Wen-Sheng Chung、Jing-Horng Liu

  DOI：10.1039/a606764f

  日期：——

  The synthesis of 7,8-disubstituted quinoxalino[2,3-d][1,2λ 4 ]oxathiine 2-oxides 7a–c, precursors for quinoxalino-o-quinodimethanes 3a–c, and their application in the Diels–Alder reactions are reported.

  报道了7,8-二取代喹咯啉[2,3-d][1,2λ4]噁二烯2-氧化物7a–c的合成，它们是喹咯啉-对奎纳二烯3a–c的前体，并且讨论了它们在Diels–Alder反应中的应用。
• PROTON EXCHANGE MEMBRANES
  申请人：Fuchs Alan

  公开号：US20110033776A1

  公开（公告）日：2011-02-10

  The present invention is directed to proton exchange membranes such as for use in fuel cells. In one embodiment, a polyetherquinoxaline is obtained by reaction between a haloquinoxaline and at least one diol, which forms a repeating unit including an ether linkage. The polyetherquinoxaline is suitable for use in a proton exchange membrane, which can be used in a fuel cell.
• US9328079B2
  申请人：——

  公开号：US9328079B2

  公开（公告）日：2016-05-03