Diethyl-carbamic acid 2'-diethylcarbamoyloxy-[1,1']binaphthalenyl-2-yl ester | 142010-76-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: Diethyl-carbamic acid 2'-diethylcarbamoyloxy-[1,1']binaphthalenyl-2-yl ester
• 英文别名: [1-[2-(diethylcarbamoyloxy)naphthalen-1-yl]naphthalen-2-yl] N,N-diethylcarbamate
• CAS: 142010-76-2
• 化学式: C₃₀H₃₂N₂O₄
• 分子量: 484.595
• InChiKey: HJYIJQLWSDDTFJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7
• 重原子数：
  36
• 可旋转键数：
  9
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  59.1
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  Diethyl-carbamic acid 2'-diethylcarbamoyloxy-[1,1']binaphthalenyl-2-yl ester 在 2-碘-1,1,1-三氟乙烷 作用下， 以79%的产率得到Diethyl-carbamic acid 2'-diethylcarbamoyloxy-3,3'-diiodo-[1,1']binaphthalenyl-2-yl ester
  参考文献：
  名称：

  A simple preparation of iodoarenes, iodoalkenes and iodoalkynes by reaction of organolithiums with 2,2,2-trifluoro-1-iodoethane

  摘要：

  Organolithium anions, generated either by deprotonation or lithium-bromine exchange, when quenched with 2,2,2-trifluoro-1-iodoethane produce cleanly the synthetically useful iodoarenes, iodoalkenes and iodoalkynes. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(99)01343-x
• 作为产物：
  描述：

  S-1,1'-联-2-萘酚 、 N,N-二乙基氯甲酰胺 在 吡啶 作用下， 以76 %的产率得到Diethyl-carbamic acid 2'-diethylcarbamoyloxy-[1,1']binaphthalenyl-2-yl ester
  参考文献：
  名称：

  4-甲基四氢吡喃：一种用于制备手性联醇催化剂和醛不对称烷基化的多功能替代溶剂

  摘要：

  在台式需氧条件下进行的两次有机金属介导的转化中，强调了 4-甲基四氢吡喃 (4-MeTHP) 作为反应介质的有益效果。 4-MeTHP 的使用使参与联萘酚 (BINOL)-氨基甲酸酯阴离子 Fries 重排的有机锂物质具有显着的稳定性，并且在有机锌试剂的不对称加成中，4-MeTHP 比其他可持续溶剂具有优越的性能。由BINOL-(双)甲酰胺衍生物催化的醛。

  DOI：

  10.1002/ejoc.202400313

文献信息

• Catalyst components for the polymerization of olefins
  申请人：Basell Poliolefine Italia S.r.l.

  公开号：EP2803678A1

  公开（公告）日：2014-11-19

  A solid catalyst component for the polymerization of olefins comprising Mg, Ti, Cl and at least an electron donor compound which is the reaction product obtained by bringing into contact a Mg compound and a Ti compound having at least a Ti-halogen bond with an electron donor selected from specific diphenol derivatives.

  一种用于烯烃聚合的固体催化剂组分，包括Mg、Ti、Cl和至少一种电子供体化合物，该化合物是通过将Mg化合物和至少含有一种Ti-卤素键的Ti化合物与选自特定二酚衍生物的电子供体接触而获得的反应产物。
• Copper-Catalysed Asymmetric Conjugate Addition of Organometallic Reagents to Linear Enones
  作者：Simon M.W Bennett、Stephen M Brown、Anthony Cunningham、Michael R Dennis、James P Muxworthy、Michael A Oakley、Simon Woodward

  DOI：10.1016/s0040-4020(00)00140-x

  日期：2000.4

  Methods for enantioselective 1,4-addition of main-group organometallics to linear enones are overviewed. Thiourethane and thioether 1,1′-binaphthyl-based ligands are effective for copper-catalysed 1,4-addition of ZnEt2 and AlR3 (R=Me, Et) to trans-alkyl-3-en-2-ones; enantioselectivities of up to 72% e.e. are attained. In comparison 1,4-addition of ZnEt2 to 2-cyclohexenone proceeds in up to 77% e.e

  概述了将主族有机金属与线性烯酮进行对映选择性1,4-加成的方法。硫代氨基甲酸酯和硫醚1,1'-联萘基配体对ZnEt 2和AlR 3（R = Me，Et）的铜催化1,4-加成反应生成反-烷基-3-en-2- one有效。对映选择性高达ee的72％。相比之下，在具有相同配体家族的情况下，ZnEt 2向2-环己烯酮的1,4-加成反应最多可产生77％ee。
• CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS
  申请人：BASELL POLIOLEFINE ITALIA S.R.L.

  公开号：US20160115261A1

  公开（公告）日：2016-04-28

  A solid catalyst component for the polymerization of olefins comprising Mg, Ti, Cl and at least an electron donor compound which is the reaction product obtained by bringing into contact a Mg compound and a Ti compound having at least a Ti-halogen bond with an electron donor selected from specific diphenol derivatives.

  用于烯烃聚合的固体催化剂组分，包括Mg、Ti、Cl和至少一种电子供体化合物，该电子供体化合物是通过将Mg化合物和至少具有Ti-卤素键的Ti化合物与特定的二苯酚衍生物中选择的电子供体接触而获得的反应产物组成的。
• Copper-Catalysed Asymmetric 1,4-Addition of Organozinc Compounds to Linear Aliphatic Enones Using 2,2′-Dihydroxy 3,3′-Dithioether Derivatives of 1,1′-Binaphthalene
  作者：Christoph Börner、Michael R. Dennis、Ekkehard Sinn、Simon Woodward

  DOI：10.1002/1099-0690(200107)2001:13<2435::aid-ejoc2435>3.0.co;2-0

  日期：2001.7
• Expedient route to 3- and 3,3′-substituted 1,1′-bi-2-naphthols by directed ortho metalation and suzuki cross coupling methods
  作者：Paul J. Cox、Wei Wang、Victor Snieckus

  DOI：10.1016/s0040-4039(00)74182-7

  日期：1992.4

  A directed ortho metalation-based route to 3- and 3,3'-substituted binaphthols 2a-c and 3a-c, including chiral materials, is described. Using the Suzuki cross coupling process, dibromo system 3a (E = Br) has been transformed into 3,3'-diaryl binaphthols 5.