C8-10-脂肪醇硫酸单酯与三乙醇胺的化合物 | 7376-31-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机硫酸及其衍生物
• 中文名称: C8-10-脂肪醇硫酸单酯与三乙醇胺的化合物
• 中文别名: 三乙醇胺硫酸盐(1:1)；硫酸TEA盐；2,2',2''-次氮基三乙醇硫酸盐
• 英文名称: triethanolamine sulfate
• 英文别名: triethanolammonium sulfate；2-[bis(2-hydroxyethyl)amino]ethanol;sulfuric acid
• CAS: 7376-31-0；117875-77-1；21121-22-2；68585-46-6
• 化学式: 2C₆H₁₆NO₃*O₄S
• 分子量: 396.459
• InChiKey: RZRILSWMGXWSJY-UHFFFAOYSA-N

物化性质

• 物理描述：
  Liquid

计算性质

• 辛醇/水分配系数(LogP)：
  -2.39
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  147
• 氢给体数：
  5
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  aluminum(III) sulfate 、 C8-10-脂肪醇硫酸单酯与三乙醇胺的化合物 在 硫酸 作用下， 以 水 为溶剂， 生成 aluminum triethanolammonium sulfate hexahydrate
  参考文献：
  名称：

  三价铝和铁的双硫酸盐与二或三乙醇铵一价阳离子的合成、表征和热分解

  摘要：

  摘要 通过在硫酸存在下蒸发M(III)硫酸盐和二乙醇硫酸铵或三乙醇硫酸铵的含水混合物，得到Al(III)和Fe(III)的双硫酸盐。所得化合物的化学计量通过元素和TG分析确定。发现它们具有以下通式： Al(HOCH 2 CH 2 ) 2 NH 2 (SO 4 ) 2 ·6H 2 O；Al(HOCH 2 CH 2 ) 3 NH(SO 4 ) 2 ·6H 2 O；Fe(HOCH 2 CH 2 ) 2 NH 2 (SO 4 ) 2 ·4H 2 O；Fe(HOCH 2 CH 2 ) 3 NH(SO 4 ) 2 ·6H 2 O。从X射线粉末衍射图可以得出结论，所研究的化合物具有不同的晶体结构。从 TG 曲线还确定，它们在低温下失水，并且无水复盐在低温下（约 523 K）分解。

  DOI：

  10.1016/0040-6031(95)02675-4
• 作为产物：
  描述：

  三乙醇胺 在 硫酸 作用下， 以 甲醇 为溶剂， 反应 26.0h， 生成 C8-10-脂肪醇硫酸单酯与三乙醇胺的化合物
  参考文献：
  名称：

  Cleaner enzymatic production of biodiesel with easy separation procedures triggered by a biocompatible hydrophilic ionic liquid

  摘要：

  一种生物相容性和亲水性离子液体被发现能够有效促进不同油资源的酶促生物柴油生产，产率优异。

  DOI：

  10.1039/c9gc03796a

文献信息

• [EN] BIOCATALYTIC PROCESSES FOR THE PREPARATION OF VILANTEROL<br/>[FR] PROCÉDÉS BIOCATALYTIQUES DE PRÉPARATION DE VILANTÉROL
  申请人：TEVA PHARMACEUTICALS INT GMBH

  公开号：WO2017001907A1

  公开（公告）日：2017-01-05

  A process for preparing Vilanterol includes a biocatalytic conversion of a ketone substrate to its corresponding alcohol, and then converting the obtained alcohol into Vilanterol. Polypeptides may be used for the biocatalytic conversion of the ketone substrate, such as 2-bromo-l-(2,2-dimethyl-4H-l,3-benzodioxin-6-yl)ethanone, to an enantiopure alcohol, (R)-2-bromo-l-(2,2-dimethyl-4H-l,3-benzodioxin-6-yl)ethanol for the preparation of Vilanterol. Also disclosed is vilanterol tartrate and solid state forms thereof for use as medicaments and for the preparation of other vilanterol salts, or of vilanterol, solid state forms and/or formulations thereof. Also disclosed is a process for the preparation of pharmaceutical formulations including vilanterol tartrate and solid state forms thereof, as well as a method of treating a person suffering from COPD and asthma by administering a therapeutically effective amount of any one or a combination of vilanterol tartrate and solid state forms thereof or a pharmaceutical composition and/or formulation comprising vilanterol tartrate and solid state forms thereof.

  制备维兰特罗的过程包括将酮底物进行生物催化转化为其相应的醇，然后将得到的醇转化为维兰特罗。多肽可用于酮底物的生物催化转化，例如将2-溴-1-(2,2-二甲基-4H-1,3-苯并二氧杂环己-6-基)乙酮转化为对映纯醇，(R)-2-溴-1-(2,2-二甲基-4H-1,3-苯并二氧杂环己-6-基)乙醇，用于制备维兰特罗。还公开了维兰特罗酒石酸盐及其作为药物用途的固态形式，以及用于制备其他维兰特罗盐或维兰特罗、固态形式和/或其制剂。还公开了一种包括维兰特罗酒石酸盐和固态形式的制备药物制剂的过程，以及通过给予治疗有效量的维兰特罗酒石酸盐和固态形式的任一种或组合，或包含维兰特罗酒石酸盐和固态形式的药物组合物和/或制剂，来治疗患有慢性阻塞性肺病(COPD)和哮喘的人的方法。
• Composition for treating inflammation which contains zinc pyrrolidonecarboxylate
  申请人：Iwasaki Keiji

  公开号：US20050271606A1

  公开（公告）日：2005-12-08

  The present invention provides a composition which suppresses inflammation of the skin. The composition of the present invention contains zinc pyrrolidonecarboxylate. The composition of the present invention may be formulated as a cosmetic or any externally applied agent.

  本发明提供一种能够抑制皮肤炎症的组合物。本发明的组合物包含吡咯烷酮羧酸锌。本发明的组合物可以制成化妆品或任何外用药剂。
• Cation-modified galactomannan polysaccharide and cosmetic composition containing the same
  申请人：Takeda Hiromitsu

  公开号：US20060275235A1

  公开（公告）日：2006-12-07

  The present invention provides a cation-modified galactomannan polysaccharide which gives excellent conditioning effects and gives good feeling and flexibility when it is used in a hair treatment composition, and improves feeling of use by conditioning effects and emulsification conditions when it is used in a skin cosmetic composition such as body cleansing agent. Concretely, the present invention provides a cation-modified galactomannan polysaccharide obtained by substituting some of hydroxyl groups contained in an cation-modified galactomannan polysaccharide which is nonionic polysaccharide and constitutes mannose as a main chain and galactose as a side chain and the composition ratio of mannose and galactose is 1:1 and obtained from albumen portion of a seed of fenugreek ( Trigonella foenum - graecum ) which is a leguminus plant, with a specific quaternary nitrogen-containing group, and a cosmetic composition containing the cation-modified cation-modified galactomannan.

  本发明提供了一种阳离子修饰的半乳糖聚糖多糖，当用于头发护理组合物时，能够提供优异的调理效果，并在使用时给人良好的感觉和柔软度；当用于皮肤化妆品组合物，例如身体清洁剂时，能够通过调理效果和乳化条件来提高使用感受。具体而言，本发明提供了一种阳离子修饰的半乳糖聚糖多糖，其通过用具有特定季铵氮含量的阳离子修饰代替非离子聚糖中含有的一些羟基，该聚糖以甘露糖为主链，以半乳糖为侧链，甘露糖和半乳糖的组成比为1:1，该聚糖来源于胡芦巴（Trigonella foenum-graecum）的种子蛋白质部分。同时，本发明还提供了一种含有该阳离子修饰的半乳糖聚糖多糖的化妆品组合物。
• Ketoreductase Polypeptides for the Production of Azetidinone
  申请人：Campopiano Onorato

  公开号：US20090162909A1

  公开（公告）日：2009-06-25

  The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize a variety of chiral compounds.

  本公开提供了经过改良的酮还原酶酶，其性能比自然存在的野生型酮还原酶酶有所提高。还提供了编码经过改良的酮还原酶酶的多核苷酸，能够表达经过改良的酮还原酶酶的宿主细胞，以及使用经过改良的酮还原酶酶合成各种手性化合物的方法。
• [EN] ALKANOLAMINE SULFATE WATER CONDITIONERS<br/>[FR] AGENTS DE CONDITIONNEMENT DE L'EAU À BASE DE SULFATE D'ALCANOLAMINE
  申请人：HUNTSMAN PETROCHEMICAL LLC

  公开号：WO2016057170A1

  公开（公告）日：2016-04-14

  Embodiments of the present disclosure include an agricultural composition containing an agriculturally active ingredient and a water conditioning agent. The water conditioning agent is an alkanolammonium sulfate. Embodiments of the present disclosure further include a method of conditioning water while maintaining comparable volatility in an agricultural formulation by adding at least one water conditioning agent to an agriculturally active ingredient, wherein the water conditioning agent comprises at least one alkanolamine sulfate.

  本公开的实施例包括一种农业组合物，其含有农业活性成分和水调节剂。水调节剂是一种烷基醇胺硫酸盐。本公开的实施例还包括一种方法，通过向至少一个农业活性成分添加至少一种水调节剂来调节水质，同时保持农业配方中可比的挥发性，其中所述水调节剂包括至少一种烷基胺硫酸盐。