7,8-bis(4-bromophenyl)-4,4-diphenyl-3-(2,4,6-trimethylphenyl)-4H-4λ5-1,2,4-triazino[3,2-c][1,2,4,5]triazaphosphinin-4-ol | 1146356-13-9

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: 7,8-bis(4-bromophenyl)-4,4-diphenyl-3-(2,4,6-trimethylphenyl)-4H-4λ5-1,2,4-triazino[3,2-c][1,2,4,5]triazaphosphinin-4-ol
• 英文别名: 7,8-Bis(4-bromophenyl)-4-hydroxy-4,4-diphenyl-3-(2,4,6-trimethylphenyl)-[1,2,4]triazino[3,2-c][1,2,4,5]triazaphosphinine
• CAS: 1146356-13-9
• 化学式: C₃₇H₃₀Br₂N₅OP
• 分子量: 751.46
• InChiKey: QDTRGLCPXMAJLW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.4
• 重原子数：
  46
• 可旋转键数：
  5
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  72.9
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  (diphenylphosphoryl){2-[5,6-bis(4-bromophenyl)-1,2,4-triazin-3-yl]hydrazino} (2,4,6-trimethylphenyl)methanol 以 四氢呋喃 为溶剂， 生成 7,8-bis(4-bromophenyl)-4,4-diphenyl-3-(2,4,6-trimethylphenyl)-4H-4λ5-1,2,4-triazino[3,2-c][1,2,4,5]triazaphosphinin-4-ol
  参考文献：
  名称：

  Synthesis and Molluscicidal Activity of Phosphorus-Containing Heterocyclic Compounds Derived from 5,6-Bis (4-bromophenyl)-3-hydrazino-1,2,4-triazine

  摘要：

  Novel N-1-(phosphoryl moiety)-N-2-(1,2,4-triazin-3-yl)hydrazines 4, 6, 8, 9 and 12, iminophosphorane 3, iminophosphane 5, 1,2,4-triazinyldiazaphospholine 7, 1,2,4,3-triazaphospholinotriazines 2, 10, 11, and 1,2,4-triazino[3,2-c][1,2,4,5] triazaphosphine 13 have been obtained via treatment 5,6-bis(4-bromophenyl)-3-hydrazino-1,2,4-triazine (1) with various polyfunctional phosphorus reagents by stirring at room temperature or refluxing for long time in tetrahydrofuran. Structures of these compounds have been deduced upon the basis of elemental and spectral data. Molluscicidal activity of the prepared compounds against Biomphalaria Alexandrina snails (the intermediate host of Schistosoma mansoni) showed considerable activities.

  DOI：

  10.1080/10426500801967864

文献信息

• Synthesis and Molluscicidal Activity of Phosphorus-Containing Heterocyclic Compounds Derived from 5,6-Bis (4-bromophenyl)-3-hydrazino-1,2,4-triazine
  作者：T. E. Ali、R. M. Abdel-Rahman、F. I. Hanafy、S. M. El-Edfawy

  DOI：10.1080/10426500801967864

  日期：2008.9.15

  Novel N-1-(phosphoryl moiety)-N-2-(1,2,4-triazin-3-yl)hydrazines 4, 6, 8, 9 and 12, iminophosphorane 3, iminophosphane 5, 1,2,4-triazinyldiazaphospholine 7, 1,2,4,3-triazaphospholinotriazines 2, 10, 11, and 1,2,4-triazino[3,2-c][1,2,4,5] triazaphosphine 13 have been obtained via treatment 5,6-bis(4-bromophenyl)-3-hydrazino-1,2,4-triazine (1) with various polyfunctional phosphorus reagents by stirring at room temperature or refluxing for long time in tetrahydrofuran. Structures of these compounds have been deduced upon the basis of elemental and spectral data. Molluscicidal activity of the prepared compounds against Biomphalaria Alexandrina snails (the intermediate host of Schistosoma mansoni) showed considerable activities.