2-ethoxy-4-((naphthalen-2-ylimino)methyl)phenyl ethyl carbonate | 1026017-19-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2-ethoxy-4-((naphthalen-2-ylimino)methyl)phenyl ethyl carbonate
• CAS: 1026017-19-5
• 化学式: C₂₂H₂₁NO₄
• 分子量: 363.413
• InChiKey: AGWKDGFAZHROLC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.52
• 重原子数：
  27.0
• 可旋转键数：
  6.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  57.12
• 氢给体数：
  0.0
• 氢受体数：
  5.0

反应信息

• 作为反应物：
  描述：

  2-ethoxy-4-((naphthalen-2-ylimino)methyl)phenyl ethyl carbonate 、 5,5-二甲基-1,3-环己二酮 以 乙醇 为溶剂， 生成
  参考文献：
  名称：

  Methyl-and ethyl carbonates derived from vanillin and vanillal in the synthesis of nitrogen-containing compounds

  摘要：

  Reactions of 4-hydroxy-3-methoxybenzaldehyde and 3-ethoxy-4-hydroxybenzildehyde with methyl and ethyl chloroformates in the presence of pyridine gave the corresponding methyl and ethyl carbonates which were brought into condensation with biphenyl-4-amine, naphthalen-1- and -2-amines. and 3-and 4-aminobenzoic acids to obtain the corresponding Schiff bases. Alkyl 4-(9,9-dimethyl-1 1-oxo-7,8,9,10,11,12-hexahydrobenzo[a]acridin-12-yl)-2-alkoxyphenyl carbonates were selectively synthesized by cascade heterocyclization of naphthalen-2-amine, 5,5-dimethylcyclohexane- 1,3-dione, and 4-formyl-2-methoxy(or ethoxy)phenyl methyl](or ethyl) carbonates. Ammonium salts were obtained from the benzoacridine derivatives and Schiff bases derived from aminobenzoic acids.

  DOI：

  10.1134/s1070363207050155
• 作为产物：
  描述：

  乙基香兰素 在 吡啶 作用下， 以 甲醇 、 苯 为溶剂， 生成 2-ethoxy-4-((naphthalen-2-ylimino)methyl)phenyl ethyl carbonate
  参考文献：
  名称：

  Methyl-and ethyl carbonates derived from vanillin and vanillal in the synthesis of nitrogen-containing compounds

  摘要：

  Reactions of 4-hydroxy-3-methoxybenzaldehyde and 3-ethoxy-4-hydroxybenzildehyde with methyl and ethyl chloroformates in the presence of pyridine gave the corresponding methyl and ethyl carbonates which were brought into condensation with biphenyl-4-amine, naphthalen-1- and -2-amines. and 3-and 4-aminobenzoic acids to obtain the corresponding Schiff bases. Alkyl 4-(9,9-dimethyl-1 1-oxo-7,8,9,10,11,12-hexahydrobenzo[a]acridin-12-yl)-2-alkoxyphenyl carbonates were selectively synthesized by cascade heterocyclization of naphthalen-2-amine, 5,5-dimethylcyclohexane- 1,3-dione, and 4-formyl-2-methoxy(or ethoxy)phenyl methyl](or ethyl) carbonates. Ammonium salts were obtained from the benzoacridine derivatives and Schiff bases derived from aminobenzoic acids.

  DOI：

  10.1134/s1070363207050155