N1,n1-双(三甲基甲硅烷基)-1,4-丁二胺 | 13435-07-9

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 中文名称: N1,n1-双(三甲基甲硅烷基)-1,4-丁二胺
• 中文别名: N,N'-双(三甲基硅基)-1,4-丁二胺
• 英文名称: N,N'-bis-(trimethylsilyl)-1,4-butanediamine
• 英文别名: N,N'-bis(trimethylsilyl)-putresceine；2,2,9,9-tetramethyl-3,8-diaza-2,9-disila-decane；N,N'-Bis-trimethylsilyl-butandiyldiamin；2,2,9,9-Tetramethyl-3,8-diaza-2,9-disila-decan；N,N'-bis(trimethylsilyl)-1,4-butanediamine；N,N'-Bis-trimethylsilyl-tetramethylendiamin；N,N'-bis(trimethylsilyl)butane-1,4-diamine
• CAS: 13435-07-9
• 化学式: C₁₀H₂₈N₂Si₂
• 分子量: 232.517
• InChiKey: RGJRTSKMSWYFCI-UHFFFAOYSA-N

物化性质

• 沸点：
  87-8°C 4mm
• 密度：
  0,825 g/cm3
• 闪点：
  13°C

计算性质

• 辛醇/水分配系数(LogP)：
  2.62
• 重原子数：
  14
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  24.1
• 氢给体数：
  2
• 氢受体数：
  2

安全信息

• 危险等级：
  3.1
• 危险品标志：
  F,C
• 危险类别码：
  R11,R34
• 危险品运输编号：
  UN 1993
• 海关编码：
  2931900090
• 包装等级：
  II
• 危险类别：
  3.1

SDS

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Section 1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE
Product identifiers
: N,N′-Bis(trimethylsilyl)-1,4-butanediamine
Product name
CAS-No. : 13435-07-9
Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances

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Section 2. HAZARDS IDENTIFICATION
Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008 [EU-GHS/CLP]
Flammable liquids (Category 2)
Skin corrosion (Category 1B)
Classification according to EU Directives 67/548/EEC or 1999/45/EC
Highly flammable. Causes burns.
Label elements
Labelling according Regulation (EC) No 1272/2008 [CLP]
Pictogram
Signal word Danger
Hazard statement(s)
H225 Highly flammable liquid and vapour.
H314 Causes severe skin burns and eye damage.
Precautionary statement(s)
P210 Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
P280 Wear protective gloves/ protective clothing/ eye protection/ face
protection.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing.
P310 Immediately call a POISON CENTER or doctor/ physician.
Supplemental Hazard none
Statements
According to European Directive 67/548/EEC as amended.
Hazard symbol(s)
R-phrase(s)
R11 Highly flammable.
R34 Causes burns.
S-phrase(s)
S16 Keep away from sources of ignition - No smoking.
S26 In case of contact with eyes, rinse immediately with plenty of water and
seek medical advice.
S27 Take off immediately all contaminated clothing.
S36/37/39 Wear suitable protective clothing, gloves and eye/face protection.
S45 In case of accident or if you feel unwell, seek medical advice immediately
(show the label where possible).
Other hazards - none

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Section 3. COMPOSITION/INFORMATION ON INGREDIENTS
Substances
Formula : C10H28N2Si2
Molecular Weight : 232,51 g/mol
Component Concentration
N,N'-Bis(trimethylsilyl)-1,4-butanediamine
CAS-No. 13435-07-9 -

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Section 4. FIRST AID MEASURES
Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Take off contaminated clothing and shoes immediately. Wash off with soap and plenty of water. Consult a
physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with
water. Consult a physician.
Most important symptoms and effects, both acute and delayed
Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and
skin., spasm, inflammation and edema of the larynx, spasm, inflammation and edema of the bronchi,
pneumonitis, pulmonary edema, burning sensation, Cough, wheezing, laryngitis, Shortness of breath,
Headache, Nausea
Indication of any immediate medical attention and special treatment needed
no data available

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Section 5. FIREFIGHTING MEASURES
Extinguishing media
Suitable extinguishing media
For small (incipient) fires, use media such as "alcohol" foam, dry chemical, or carbon dioxide. For large
fires, apply water from as far as possible. Use very large quantities (flooding) of water applied as a mist or
spray; solid streams of water may be ineffective. Cool all affected containers with flooding quantities of
water.
Special hazards arising from the substance or mixture
Carbon oxides, nitrogen oxides (NOx), silicon oxides
Advice for firefighters
Wear self contained breathing apparatus for fire fighting if necessary.
Further information
Use water spray to cool unopened containers.

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Section 6. ACCIDENTAL RELEASE MEASURES
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid breathing vapors, mist or gas. Ensure adequate ventilation.
Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to
form explosive concentrations. Vapours can accumulate in low areas.
Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains.
Methods and materials for containment and cleaning up
Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and
place in container for disposal according to local regulations (see section 13).
Reference to other sections
For disposal see section 13.

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Section 7. HANDLING AND STORAGE
Precautions for safe handling
Avoid inhalation of vapour or mist.
Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic
charge.
Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are
opened must be carefully resealed and kept upright to prevent leakage.
Specific end use(s)
no data available

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Section 8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Control parameters
Components with workplace control parameters
Exposure controls
Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and
at the end of workday.
Personal protective equipment
Eye/face protection
Tightly fitting safety goggles. Faceshield (8-inch minimum). Use equipment for eye protection
tested and approved under appropriate government standards such as NIOSH (US) or EN
166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and
the standard EN 374 derived from it.
Body Protection
Complete suit protecting against chemicals, Flame retardant antistatic protective clothing, The type
of protective equipment must be selected according to the concentration and amount of the
dangerous substance at the specific workplace.
Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator
with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup
to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air
respirator. Use respirators and components tested and approved under appropriate government
standards such as NIOSH (US) or CEN (EU).

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Section 9. PHYSICAL AND CHEMICAL PROPERTIES
Information on basic physical and chemical properties
a) Appearance Form: liquid
b) Odour no data available
c) Odour Threshold no data available
d) pH no data available
e) Melting point/freezing no data available
point
f) Initial boiling point and 87 - 88 °C at 5 hPa
boiling range
g) Flash point 14 °C - closed cup
h) Evaporation rate no data available
i) Flammability (solid, gas) no data available
j) Upper/lower no data available
flammability or
explosive limits
k) Vapour pressure no data available
l) Vapour density no data available
m) Relative density 0,825 g/cm3
n) Water solubility no data available
o) Partition coefficient: n- no data available
octanol/water
p) Auto-ignition no data available
temperature
q) Decomposition no data available
temperature
r) Viscosity no data available
s) Explosive properties no data available
t) Oxidizing properties no data available
Other safety information
no data available

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Section 10. STABILITY AND REACTIVITY
Reactivity
no data available
Chemical stability
no data available
Possibility of hazardous reactions
no data available
Conditions to avoid
Heat, flames and sparks. Extremes of temperature and direct sunlight.
Incompatible materials
Strong oxidizing agents, acids, Alcohols
Hazardous decomposition products
Other decomposition products - no data available

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Section 11. TOXICOLOGICAL INFORMATION
Information on toxicological effects
Acute toxicity
no data available
Skin corrosion/irritation
no data available
Serious eye damage/eye irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as
probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
no data available
Specific target organ toxicity - single exposure
no data available
Specific target organ toxicity - repeated exposure
no data available
Aspiration hazard
no data available
Potential health effects
Inhalation
May be harmful if inhaled. Material is extremely destructive to the tissue of
the mucous membranes and upper respiratory tract.
Ingestion May be harmful if swallowed. Causes burns.
Skin May be harmful if absorbed through skin. Causes skin burns.
Eyes
Causes eye burns.
Signs and Symptoms of Exposure
Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and
skin., spasm, inflammation and edema of the larynx, spasm, inflammation and edema of the bronchi,
pneumonitis, pulmonary edema, burning sensation, Cough, wheezing, laryngitis, Shortness of breath,
Headache, Nausea
Additional Information
RTECS: Not available

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Section 12. ECOLOGICAL INFORMATION
Toxicity
no data available
Persistence and degradability
no data available
Bioaccumulative potential
no data available
Mobility in soil
no data available
Results of PBT and vPvB assessment
no data available
Other adverse effects
no data available

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Section 13. DISPOSAL CONSIDERATIONS
Waste treatment methods
Product
Burn in a chemical incinerator equipped with an afterburner and scrubber but exert extra care in igniting
as this material is highly flammable. Offer surplus and non-recyclable solutions to a licensed disposal
company. Contact a licensed professional waste disposal service to dispose of this material.
Contaminated packaging
Dispose of as unused product.

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Section 14. TRANSPORT INFORMATION
UN number
ADR/RID: 2733 IMDG: 2733 IATA: 2733
UN proper shipping name
ADR/RID: POLYAMINES, FLAMMABLE, CORROSIVE, N.O.S. (N,N'-Bis(trimethylsilyl)-1,4-
butanediamine)
IMDG: POLYAMINES, FLAMMABLE, CORROSIVE, N.O.S. (N,N'-Bis(trimethylsilyl)-1,4-
butanediamine)
IATA: Polyamines, flammable, corrosive, n.o.s. (N,N'-Bis(trimethylsilyl)-1,4-butanediamine)
Transport hazard class(es)
ADR/RID: 3 (8) IMDG: 3 (8) IATA: 3 (8)
Packaging group
ADR/RID: II IMDG: II IATA: II
Environmental hazards
ADR/RID: no IMDG Marine Pollutant: no IATA: no
Special precautions for user
no data available

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SECTION 15 - REGULATORY INFORMATION
N/A

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SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  β-丙内酯 、 N1,n1-双(三甲基甲硅烷基)-1,4-丁二胺 以 四氢呋喃 为溶剂， 反应 6.0h， 以76%的产率得到N,N-bis(trimethylsilylpropionate)-puresceine
  参考文献：
  名称：

  Taddei, Maurizio; Tempesti, Federica, Synthetic Communications, 1985, vol. 15, # 11, p. 1019 - 1024

  摘要：

  DOI：
• 作为产物：
  描述：

  四亚甲基二胺 、 三甲基硅烷基二乙胺 在 三甲基氯硅烷 作用下， 以 二氯甲烷 为溶剂， 以95%的产率得到N1,n1-双(三甲基甲硅烷基)-1,4-丁二胺
  参考文献：
  名称：

  Taddei, Maurizio; Tempesti, Federica, Synthetic Communications, 1985, vol. 15, # 11, p. 1019 - 1024

  摘要：

  DOI：

文献信息

• ACTIVE-SITE-DIRECTED ENZYME-ACTIVATED N-NITROSOAMIDE INHIBITORS OF TRYPSIN
  作者：Yulong Chen、Emil H. White

  DOI：10.1080/00304949609355908

  日期：1996.2
• Über darstellung und eigenschaften von monomeren, polymeren und cyclischen methylsilyldiaminen
  作者：Von Friedrich August Henglein、Klaus Lienhard

  DOI：10.1002/macp.1959.020320121

  日期：——

  AbstractDurch Reaktion von Trimethylchlorsilan, Dimethyldichlorsilan und Dimethyl‐bis‐[diäthylamino]‐silan mit Äthylendiamin, Dimethyläthylendiamin, Tetramethylendiamin und Hexamethylendiamin wurden verschiedene monomere, polymere und cyclische Methylsilyldiamine dargestellt. Die Eigenschaften der erhaltenen Verbindungen werden beschrieben.
• TADDEI, M.;TEMPESTI, F., SYNTH. COMMUN., 1985, 15, N 11, 1019-1024
  作者：TADDEI, M.、TEMPESTI, F.

  DOI：——

  日期：——
• Taddei, Maurizio; Tempesti, Federica, Synthetic Communications, 1985, vol. 15, # 11, p. 1019 - 1024
  作者：Taddei, Maurizio、Tempesti, Federica

  DOI：——

  日期：——