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(1'S,2'R)-2-(1'-benzyl-3'-dimethylamino-2'-methyl-1'-phenyl-propoxy)dinaphtho[2,1-d:1',2'-f](1,3,2) dioxaphosphepine | 479253-09-3

中文名称
——
中文别名
——
英文名称
(1'S,2'R)-2-(1'-benzyl-3'-dimethylamino-2'-methyl-1'-phenyl-propoxy)dinaphtho[2,1-d:1',2'-f](1,3,2) dioxaphosphepine
英文别名
(2R,3S)-3-(12,14-dioxa-13-phosphapentacyclo[13.8.0.02,11.03,8.018,23]tricosa-1(15),2(11),3,5,7,9,16,18,20,22-decaen-13-yloxy)-N,N,2-trimethyl-3,4-diphenylbutan-1-amine
(1'S,2'R)-2-(1'-benzyl-3'-dimethylamino-2'-methyl-1'-phenyl-propoxy)dinaphtho[2,1-d:1',2'-f](1,3,2) dioxaphosphepine化学式
CAS
479253-09-3
化学式
C39H36NO3P
mdl
——
分子量
597.693
InChiKey
JZPOLOLCAURGTK-DJRZPZLQSA-N
BEILSTEIN
——
EINECS
——
  • 物化性质
  • 计算性质
  • ADMET
  • 安全信息
  • SDS
  • 制备方法与用途
  • 上下游信息
  • 反应信息
  • 文献信息
  • 表征谱图
  • 同类化合物
  • 相关功能分类
  • 相关结构分类

计算性质

  • 辛醇/水分配系数(LogP):
    10
  • 重原子数:
    44
  • 可旋转键数:
    8
  • 环数:
    7.0
  • sp3杂化的碳原子比例:
    0.18
  • 拓扑面积:
    38.8
  • 氢给体数:
    0
  • 氢受体数:
    4

上下游信息

  • 上游原料
    中文名称 英文名称 CAS号 化学式 分子量

反应信息

  • 作为反应物:
    描述:
    (1'S,2'R)-2-(1'-benzyl-3'-dimethylamino-2'-methyl-1'-phenyl-propoxy)dinaphtho[2,1-d:1',2'-f](1,3,2) dioxaphosphepine 、 di(rhodium)tetracarbonyl dichloride 以 二氯甲烷 为溶剂, 以82%的产率得到chloro[(1'S,2'R)-2-(1'-benzyl-3'-dimethylamino-2'-methyl-1'-phenyl-propoxy)dinaphtho[2,1-d:1',2'-f](1,3,2) dioxaphosphepine]monocarbonylrhodium(I)
    参考文献:
    名称:
    New amino-, imino- and oxazolinophosphites based on 1,1′-bi-2-naphtol: coordination and catalytic properties
    摘要:
    A series of the new chiral BINOL-based phosphite P,N-hybrid ligands was prepared. The coordination behavior of all the ligands was studied and the neutral complexes [Rh(CO)Cl(P<^>N)] were synthesized in order to characterize a degree of the electronic non-symmetry of donating centers. Also the neutral and cationic complexes cis-[PdCl2(eta(2)-P<^>N=)], cis-[PdCl2(eta(1)-P<^>N=)(2)], cis-[PdCl(eta(2)-P<^>N=)(eta(1)-P<^>N=)]Cl-+(-), [Pd(allyl)(eta(2)-P<^>N=)]X-+(-) (X- = Cl-, BF4-) were obtained and characterized. The new P,N-hydrid ligands gave up to 81% ee in the enantioselective Pd-catalyzed alkylation of 3-penten-2-yl carbonate by dimethyl malonate and up to 60% ee in the Rh-catalyzed hydrosilylation of acetophenone and acetylferrocene by diphenylsilane. (C) 2002 Elsevier Science B.V. All rights reserved.
    DOI:
    10.1016/s0022-328x(02)01561-9
  • 作为产物:
    描述:
    (R)-(1,1′-联萘-2,2′-二氧)氯膦(2S,3R)-(+)-4-二甲氨基-1,2-二苯基-3-甲基-2-丁醇三乙胺 作用下, 以 甲苯 为溶剂, 以89%的产率得到(1'S,2'R)-2-(1'-benzyl-3'-dimethylamino-2'-methyl-1'-phenyl-propoxy)dinaphtho[2,1-d:1',2'-f](1,3,2) dioxaphosphepine
    参考文献:
    名称:
    New amino-, imino- and oxazolinophosphites based on 1,1′-bi-2-naphtol: coordination and catalytic properties
    摘要:
    A series of the new chiral BINOL-based phosphite P,N-hybrid ligands was prepared. The coordination behavior of all the ligands was studied and the neutral complexes [Rh(CO)Cl(P<^>N)] were synthesized in order to characterize a degree of the electronic non-symmetry of donating centers. Also the neutral and cationic complexes cis-[PdCl2(eta(2)-P<^>N=)], cis-[PdCl2(eta(1)-P<^>N=)(2)], cis-[PdCl(eta(2)-P<^>N=)(eta(1)-P<^>N=)]Cl-+(-), [Pd(allyl)(eta(2)-P<^>N=)]X-+(-) (X- = Cl-, BF4-) were obtained and characterized. The new P,N-hydrid ligands gave up to 81% ee in the enantioselective Pd-catalyzed alkylation of 3-penten-2-yl carbonate by dimethyl malonate and up to 60% ee in the Rh-catalyzed hydrosilylation of acetophenone and acetylferrocene by diphenylsilane. (C) 2002 Elsevier Science B.V. All rights reserved.
    DOI:
    10.1016/s0022-328x(02)01561-9
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文献信息

  • New amino-, imino- and oxazolinophosphites based on 1,1′-bi-2-naphtol: coordination and catalytic properties
    作者:K.N Gavrilov、O.G Bondarev、R.V Lebedev、A.I Polosukhin、A.A Shyryaev、S.E Lyubimov、P.V Petrovskii、S.K Moiseev、V.N Kalinin、N.S Ikonnikov、V.A Davankov、A.V Korostylev
    DOI:10.1016/s0022-328x(02)01561-9
    日期:2002.8
    A series of the new chiral BINOL-based phosphite P,N-hybrid ligands was prepared. The coordination behavior of all the ligands was studied and the neutral complexes [Rh(CO)Cl(P<^>N)] were synthesized in order to characterize a degree of the electronic non-symmetry of donating centers. Also the neutral and cationic complexes cis-[PdCl2(eta(2)-P<^>N=)], cis-[PdCl2(eta(1)-P<^>N=)(2)], cis-[PdCl(eta(2)-P<^>N=)(eta(1)-P<^>N=)]Cl-+(-), [Pd(allyl)(eta(2)-P<^>N=)]X-+(-) (X- = Cl-, BF4-) were obtained and characterized. The new P,N-hydrid ligands gave up to 81% ee in the enantioselective Pd-catalyzed alkylation of 3-penten-2-yl carbonate by dimethyl malonate and up to 60% ee in the Rh-catalyzed hydrosilylation of acetophenone and acetylferrocene by diphenylsilane. (C) 2002 Elsevier Science B.V. All rights reserved.
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