2,2′-azobis(2-methylpropionamidine)dihydrochloride

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 2,2′-azobis(2-methylpropionamidine)dihydrochloride
• 英文别名: 2,2'-azobis(2-methylpropanimidamidine) dihydrochloride；2,2'-azo-bis-(2-methylpropionamidine)-dihydrochloride；2, 2'-azobis[2-methylpropionamidine] dihydrochloride；2,2′-Azobis(2-amidinopropane) dihydrochloride；2,2'-azobis(2-methylpropionamidine) dihydrochloride；2,2’-azobisisobutylamidine dihydrochloride
• 化学式: C₈H₁₈N₆*2ClH
• 分子量: 271.193
• InChiKey: QMYCJCOPYOPWTI-IERUDJENSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.29
• 重原子数：
  15.0
• 可旋转键数：
  4.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  124.46
• 氢给体数：
  4.0
• 氢受体数：
  4.0

反应信息

• 作为反应物：
  描述：

  4-甲硫基-2-氧代-丁酸 、 2,2′-azobis(2-methylpropionamidine)dihydrochloride 以 phosphate buffer 为溶剂， 反应 1.67h， 生成 乙烯
  参考文献：
  名称：

  Total oxidant scavenging capacity (TOSC) of microsomal and cytosolic fractions from Antarctic, Arctic and Mediterranean scallops: differentiation between three potent oxidants

  摘要：

  The enhanced formation of reactive oxygen species (ROS) is a common pathway of toxicity induced by stressful environmental conditions. In polar environments, characterization of antioxidant defences in key sentinel species may be of particular value as early detection biomarkers of unforeseen effects of human activities which are progressively increasing in these remote areas.The complexities associated with predicting the consequences at the 'organism level' of variations of specific antioxidant defences have been recently overcome by the ability to quantify an index of specific biological resistance to various kinds of ROS.The total oxyradical scavenging capacity (TOSC) assay has been used in three species of scallops for quantifying their ability to neutralize peroxyl (ROO.) and hydroxyl ((OH)-O-.) radicals and peroxynitrite (HOONO). Adamussium colbecki and Chlamys islandicus represent key organisms for monitoring Antarctic and Arctic regions while Pecten jacobaeus was chosen for a comparison with a related temperate species. TOSC values for ROO. were significantly higher in A. colbecki indicating this species as the most efficient scavenger of ROO.. Mediterranean scallops had the lowest TOSC for ROO.. A. colbecki also exhibited the highest scavenging capacity for (OH)-O-. with values more than 2-fold greater than for C. islandicus and P. jacobaeus. TOSC for HOONO was lower for all scallops as compared to those for ROO. or (OH)-O-.. TOSC for microsomes was not significantly different among the species for any ROS studied, and the percentage contribution to the specific TOSC for the various oxidants of microsomes of all scallops accounted for 1-3% of the total TOSC of the post-mitochondrial fraction. The specific TOSC of scallop microsomes for (OH)-O-. was approximately ten times lower than that for ROO. or HOONO.The higher basal capability of the Antarctic scallop to neutralize different reactive oxygen species is discussed in terms of a possible adaptation to this extreme environment and TOSC is validated as a quantifiable measure of susceptibility to oxidative stress in marine organisms. (C) 2000 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s0166-445x(99)00070-3

文献信息

• [EN] PARTICLES FOR ELECTROPHORETIC DISPLAYS<br/>[FR] PARTICULES POUR ÉCRANS D'AFFICHAGE ÉLECTROPHORÉTIQUES
  申请人：MERCK PATENT GMBH

  公开号：WO2012019704A1

  公开（公告）日：2012-02-16

  This invention relates to coloured polymer particles preferably with surface functionality for charge retention, a process for their preparation, the use of these particles for the preparation of an electrophoretic device, colour electrophoretic displays comprising such particle, and new polymerisable dyes.

  这项发明涉及彩色聚合物颗粒，最好具有表面功能以保持电荷，一种它们的制备方法，利用这些颗粒制备电泳装置，包括这种颗粒的彩色电泳显示器，以及新的可聚合染料。
• Aqueous photoprotective compositions comprising acrylamido-2-methylpropanesulfonic acid polymers and 4,4-diarylbutadiene UV-A sunscreens
  申请人：L'OREAL

  公开号：US20040228815A1

  公开（公告）日：2004-11-18

  Photoprotective compositions, e.g., oil-in-water or water-in-oil emulsions, well suited for the photoprotection of the skin, lips and/or hair against the damaging effects of UV-radiation, comprise at least one aqueous phase, at least one oily phase, at least one partially or completely neutralized, crosslinked or non-crosslinked water-soluble or water-dispersible acrylamido-2-methylpropanesulfonic acid (AMPS) polymer and at least one UV radiation-screening system, said at least one screening system comprising at least one 4,4-diarylbutadiene UV-A-screening agent

  光保护组合物，例如油包水或水包油乳液，非常适合用于保护皮肤、嘴唇和/或头发免受紫外辐射的损害作用，包括至少一个水相，至少一个油相，至少一个部分或完全中和的、交联或非交联的水溶性或水分散性丙烯酰胺-2-甲基丙烯磺酸（AMPS）聚合物，以及至少一个UV辐射屏蔽系统，所述至少一个屏蔽系统包括至少一个4,4-二芳基丁二烯UV-A屏蔽剂
• Perfluorinated amide salts and their uses as ionic conducting materials
  申请人：——

  公开号：US20020009650A1

  公开（公告）日：2002-01-24

  The invention concerns ionic compounds in which the anionic load has been delocalized. A compound disclosed by the invention is comprised of an amide or one of its salts, including an anionic portion combined with at least one cationic portion M +m in sufficient numbers to ensure overall electronic neutrality; the compound is further comprised of M as a hydroxonium, a nitrosonium NO + , an ammonium —NH 4 +, a metallic cation with the valence m, an organic cation with the valence m, or an organometallic cation with the valence m. The anionic portion matches the formula R F —SO x —N − Z, wherein R F is a perfluorinated group, x is 1 or 2, and Z is an electroattractive substituent. The compounds can be used notably for ionic conducting materials, electronic conducting materials, colorants, and the catalysis of various chemical reactions.

  该发明涉及离子化合物，其中阴离子载荷已被解离。该发明揭示的一种化合物由酰胺或其盐之一组成，包括与至少一个阳离子部分M+min结合以确保整体电子中性；该化合物进一步由M作为氢氧离子、亚硝基 NO+、铵离子—NH4+、具有价态m的金属阳离子、具有价态m的有机阳离子，或具有价态m的有机金属阳离子组成。阴离子部分符合公式RF—SOx—N−Z，其中RF是全氟化基团，x为1或2，Z是一个电子吸引取代基。这些化合物可以用于离子导电材料、电子导电材料、着色剂以及各种化学反应的催化。
• Novel compounds comprising a thiocarbonyl-sulfanyl group, which can be used for the radical synthesis of-alpha-perfluoroalkylamines
  申请人：Zard Samir

  公开号：US20060122404A1

  公开（公告）日：2006-06-08

  The invention relates to compounds having the general formula (I), the method of preparation thereof and the use thereof in organic radical synthesis. The invention also relates to compounds having the formula (II), the method of preparation thereof and a method for preparing compounds having the formula (VIII).

  该发明涉及具有通式（I）的化合物，其制备方法及在有机自由基合成中的用途。该发明还涉及具有通式（II）的化合物，其制备方法以及制备具有通式（VIII）的化合物的方法。
• COSMETIC COMPOSITION COMPRISING AT LEAST ONE CATIONIC COPOLYMER AND AT LEAST ONE ANIONIC ASSOCIATIVE POLYMER AND COSMETIC TREATMENT PROCESSES USING SAID COMPOSITION
  申请人：BIGANSKA Olga

  公开号：US20090074692A1

  公开（公告）日：2009-03-19

  The disclosure relates to novel cosmetic compositions comprising, in a cosmetically acceptable medium: (i) at least one cationic polymer which are produced by polymerization of a mixture of monomers comprising: a) at least one vinyl monomer substituted with at least one amino group, b) at least one hydrophobic nonionic vinyl monomer, c) at least one associative vinyl monomer, and e) at least one hydroxylated nonionic vinyl monomer, and (ii) at least one anionic associative polymers.

  该披露涉及新型化妆品组合物，包括在适合用于化妆的介质中的：(i) 至少一种阳离子聚合物，其由包括：a) 至少一种含有至少一个氨基团的乙烯单体，b) 至少一种疏水非离子乙烯单体，c) 至少一种关联性乙烯单体，和e) 至少一种羟基化非离子乙烯单体的单体混合物聚合而成，以及(ii) 至少一种阴离子关联性聚合物。