3-O-tetradecyl-L-ascorbic acid | 106396-33-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氢呋喃
• 英文名称: 3-O-tetradecyl-L-ascorbic acid
• 英文别名: (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-3-tetradecoxy-2H-furan-5-one
• CAS: 106396-33-2
• 化学式: C₂₀H₃₆O₆
• 分子量: 372.502
• InChiKey: ZQDRNBBCEGUCAJ-FUHWJXTLSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  26
• 可旋转键数：
  16
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.85
• 拓扑面积：
  96.2
• 氢给体数：
  3
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  5,6-O-isopropylidene-3-O-tetradecyl-L-ascorbic acid 生成 3-O-tetradecyl-L-ascorbic acid
  参考文献：
  名称：

  NIHRO, YASUNORI;MIYATAKA, HIDEKI;SUDO, TADAMITSU;MATSUMOTO, HITOSHI;SATOH+, J. MED. CHEM., 34,(1991) N, C. 2152-2157

  摘要：

  DOI：

文献信息

• Regioselective Synthesis of 3-O-Alkyl Ethers of Ascorbic Acid without Protecting Groups in a Single Step
  作者：Uwe Beifuss、Olaf Kunz、Gundula Voss

  DOI：10.1016/s0040-4020(99)01013-3

  日期：2000.1

  The direct alkylation of L-ascorbic acid (vitamin C) with alkyl mesylates using sodium hydrogen carbonate as a base without protecting groups proceeds regioselectively and yields the corresponding 3-O-alkyl ethers of L-ascorbic acid exclusively. (C) 2000 Elsevier Science Ltd. All rights reserved.
• METHOD AND COMPOSITION FOR THERMALLY STABILIZING VITAMIN C WITHIN NANO LAYERS OF MONTMORILLONITE CLAY
  申请人：Goonesekara Chandhi S.

  公开号：US20110184006A1

  公开（公告）日：2011-07-28

  A thermally stable Vitamin C composition containing montmorillonite, an organic acid containing L-ascorbic acid or a derivative thereof, a divalent cation present within nanolayers of the montmorillonite, wherein the organic acid is combined with the divalent cation within the nanolayers to form an organic acid-montmorillonite chelate.
• NIHRO, YASUNORI;MIYATAKA, HIDEKI;SUDO, TADAMITSU;MATSUMOTO, HITOSHI;SATOH+, J. MED. CHEM., 34,(1991) N, C. 2152-2157
  作者：NIHRO, YASUNORI、MIYATAKA, HIDEKI、SUDO, TADAMITSU、MATSUMOTO, HITOSHI、SATOH+

  DOI：——

  日期：——