4-癸基苯-1,3-二醇 | 53156-47-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 中文名称: 4-癸基苯-1,3-二醇
• 英文名称: 4-decylresorcinol
• 英文别名: 4-Decyl-resorcin；2.4-Dihydroxy-1-decyl-benzol；2.4-Dioxy-1-n-decyl-benzol；4-n-Decyl-resorcin；1,3-Benzenediol, 4-decyl-；4-decylbenzene-1,3-diol
• CAS: 53156-47-1
• 化学式: C₁₆H₂₆O₂
• 分子量: 250.381
• InChiKey: QJZPSSRNQMRETN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  18
• 可旋转键数：
  9
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4-癸基苯-1,3-二醇 在 磺酰氯 、 乙醚 作用下， 生成 4-chloro-6-decyl-resorcinol
  参考文献：
  名称：

  Tomita et al., Yakugaku Zasshi/Journal of the Pharmaceutical Society of Japan, 1951, vol. 71, p. 593

  摘要：

  DOI：
• 作为产物：
  描述：

  1-(2,4-dihydroxyphenyl)-decan-1-one 在 盐酸 、 amalgamated zinc 作用下， 以 乙醇 为溶剂， 以57%的产率得到4-癸基苯-1,3-二醇
  参考文献：
  名称：

  Mizobuchi, Shigeyuki; Sato, Yuko, Agricultural and Biological Chemistry, 1985, vol. 49, # 5, p. 1327 - 1334

  摘要：

  DOI：

文献信息

• MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME
  申请人：TABATA Masayoshi

  公开号：US20110224343A1

  公开（公告）日：2011-09-15

  The present invention provides a modifier for aromatic polyesters which enhances the melt fluidity of aromatic polyesters without a significant decrease in the heat resistance of the aromatic polyesters, and an aromatic polyester resin composition including the modifier for aromatic polyesters. The present invention relates to a modifier for aromatic polyesters comprising polyhydric phenol residues and residues of aromatic polycarboxylic acid, acid halide or acid anhydride thereof, and the modifier comprises a material having a structure composed of a first residue selected from the group consisting of divalent residues represented by Formula (I): —Ar—W 1 x —Ar— and by Formula (II): —Ar—, the first residues being bonded to two identical or different second residues selected from the group consisting of monovalent residues represented by Formula (III): and monovalent residues represented by Formula (IV): —O—C(O)—R 7 —.

  本发明提供了一种用于芳香族聚酯的改性剂，可以增强芳香族聚酯的熔融流动性，而不明显降低芳香族聚酯的耐热性，以及包括该改性剂的芳香族聚酯树脂组合物。本发明涉及一种用于芳香族聚酯的改性剂，包括多羟基酚残基和芳香族多羧酸、酸卤或其酸酐残基，该改性剂包括具有以下结构的材料：第一残基，选择自由式(I)所代表的二价残基：—Ar—W1x—Ar—和自由式(II)所代表的：—Ar—，第一残基与选择自由式(III)所代表的单价残基：和自由式(IV)所代表的单价残基：—O—C(O)—R7—的两个相同或不同的第二残基结合。
• Chemical synthesis and tyrosinase inhibitory activity of resorcinol alkyl glucosides, hydroxyalkyl resorcinols, and alkyl resorcinols
  作者：Wakana Ishioka、Ken-ichi Nihei

  DOI：10.1016/j.molstruc.2022.133668

  日期：2022.11

  length of the alkyl chain. The gap in the activities between the C2 and C3 analogs was decreased in the order: resorcinol alkyl glucosides>hydroxyalkyl resorcinols>alkyl resorcinols. It indicates that the sugar and hydroxy groups interfered in the functions when they were adjacent to the resorcinol ring. C14 analog 22 (IC50 = 0.81 µM) with the poor water solubility showed slightly weak activity compared

  为了开发新型酪氨酸酶抑制剂，间苯二酚烷基葡糖苷7 – 12通过 Wittig 和/或 Horner-Wadsworth-Emmons 反应合成，其中 Koenigs-Knorr 糖基化是关键步骤。对于酪氨酸酶催化的氧化，观察到 7-12 的半数最大抑制浓度 (IC 50 ) 为35.9-0.39 µM。还评估了羟烷基间苯二酚13-18和烷基间苯二酚19-24的酪氨酸酶抑制活性，以研究糖对其结构的影响。因此，IC 50的13 – 18和19 – 24分别为 9.27–0.32 µM 和 1.58–0.53 µM。随着烷基链长度的增加，大多数衍生物变得更有效。C 2和C 3类似物之间的活性差距按顺序减小：间苯二酚烷基糖苷>羟烷基间苯二酚>烷基间苯二酚。这表明糖和羟基在与间苯二酚环相邻时会干扰功能。水溶性差的C 14类似物22 (IC 50  = 0.81 µM) 与 C 10类似物21 (IC
• AROMATIC POLYESTER
  申请人：Muroran Institute of Technology

  公开号：EP2479203A1

  公开（公告）日：2012-07-25

  The present invention provides an aromatic polyester which is substantially free from the occurrence of coloration and retains significantly high transparency even after being thermally processed at high temperature and which has high flowability. The aromatic polyester contains a polyhydric phenol residue and a residue of any one of aromatic polycarboxylic acid, halide thereof, and anhydride thereof, and terminals of the aromatic polyester have a structure represented by the formula -C(O)-R. The aromatic polyester has an end-capping rate of 90% or higher and a weight average molecular weight (Mw) ranging from 3,000 to 1,000,000.

  本发明提供了一种芳香族聚酯，该聚酯基本上不会发生着色，即使在高温热加工后仍能保持明显的高透明度，并且具有高流动性。芳香族聚酯含有多羟基苯酚残留物和芳香族多羧酸、其卤化物和其酸酐中任意一种的残留物，芳香族聚酯的端基具有式 -C(O)-R 所代表的结构。芳香族聚酯的端盖率为 90% 或更高，重量平均分子量（Mw）为 3,000 至 1,000,000 之间。
• HAIR DEFORMATION TREATMENT AGENT
  申请人：Kao Corporation

  公开号：EP3228300A1

  公开（公告）日：2017-10-11

  An agent for hair deforming treatment comprising the following components (A), (B) and (C) : (A) glyoxylic acid, or a hydrate or a salt thereof, (B) resorcin, and (C) water, wherein the molar ratio of the content of the component (B) to the content of the component (A), (B)/(A), is 0.2 or more and 5 or less.

  一种用于头发变形处理的药剂，由以下成分组成(A)、(B)和(C)： (A) 乙二酸，或其水合物或鹽、 (B) 间苯二酚，以及 (C) 水、 其中(B)组分含量与(A)组分含量的摩尔比(B)/(A)为 0.2 或 0.2 以上 5 或 5 以下。
• Peptides for skin rejuvenation and methods of using the same
  申请人：Anteis SA

  公开号：US10543195B2

  公开（公告）日：2020-01-28

  The invention provides compositions for stimulating the formation of one or more extracellular matrix components that contain a lipoaminoacid derivative of the tripeptide carnosine such as N-Octanoyl Carnosine. Also provided are compositions containing N-Octanoyl Carnosine in combination with selected tripeptide and/or tetrapeptides as well as pharmaceutical and/or cosmetic compositions containing such compositions. The invention further provides methods of using the compositions and compositions of the invention to treat, alleviate, and/or ameliorate a symptom, condition, disorder, or disease of the skin or mucosa, wherein the symptom, condition, disorder, or disease is associated with changes in extracellular matrix components.

  本发明提供了刺激一种或多种细胞外基质成分形成的组合物，这些组合物含有三肽肉碱的脂氨基酸衍生物，如 N-辛酰肉碱。本发明还提供了含有 N-辛酰肉碱与所选三肽和/或四肽的组合物，以及含有此类组合物的药物和/或化妆品组合物。本发明进一步提供了使用本发明的组合物和组合物治疗、减轻和/或改善皮肤或粘膜的症状、状况、失调或疾病的方法，其中症状、状况、失调或疾病与细胞外基质成分的变化有关。