Disodium 4-((3-carboxylato-4-hydroxy-1-naphthyl)phenylmethylene)-1,4-dihydro-1-oxo-2-naphthoate | 5715-76-4

• 物质功能分类: 化学试剂 - 有机试剂 - 多环化合物
• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: Disodium 4-((3-carboxylato-4-hydroxy-1-naphthyl)phenylmethylene)-1,4-dihydro-1-oxo-2-naphthoate
• 英文别名: disodium;4-[(Z)-(3-carboxy-4-oxonaphthalen-1-ylidene)-phenylmethyl]-1-oxidonaphthalene-2-carboxylate
• CAS: 5715-76-4
• 化学式: C29H16Na2O6
• 分子量: 506.4
• InChiKey: YMXSSEMZYBUPOI-PJXKUKQXSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  -3.25
• 重原子数：
  37
• 可旋转键数：
  2
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  118
• 氢给体数：
  1
• 氢受体数：
  6

安全信息

• 安全说明：
  S24/25

文献信息

• Indicating devices based on lateral diffusion of a mobile phase through a non-porous stationary phase
  申请人：JP LABORATORIES, INC

  公开号：US10451595B2

  公开（公告）日：2019-10-22

  This invention relates to indicating devices, such as time-temperature indicators based on lateral diffusion of a vapor of a solid and/or liquid mobile phase (e.g., a sublimeable dye or an activator) through a non-porous stationary phase, such as a thin layer of a polymeric material. The lateral diffusion of the mobile phase creates a noticeable boundary in the stationary phase whose movement depends upon processes, such as time and temperature.

  本发明涉及指示装置，如基于固体和/或液体流动相（如可升华染料或活化剂）的蒸汽通过无孔固定相（如聚合物材料薄层）的横向扩散的时间-温度指示器。流动相的横向扩散在固定相中形成一个明显的边界，其移动取决于时间和温度等过程。
• Color changing steam sterilization indicator
  申请人：——

  公开号：US20030211618A1

  公开（公告）日：2003-11-13

  There is provided a device ( 10 ) for monitoring sterilization of a material with steam comprising at least one layer ( 20 ), having incorporated therein an isomeric indicator ( 22 ), capable of undergoing at least one color change and optionally a controller ( 23 ) for said indicator capable of influencing the time and temperature required for said color change when contact with steam. Composed of polymeric binder ( 21 ).

  提供了一个装置 ( 10 )用于监测用蒸汽对材料进行灭菌的情况，该装置包括至少一层( 20 )，其中含有异构指示剂 ( 22 20 ），其中包含一个异构指示器（22 23 控制器（23），该指示器能够在与蒸汽接触时影响上述颜色变化所需的时间和温度。由聚合物粘合剂 ( 21 ).
• Method and device for detecting ammonia odors and helicobacter pylori urease infection
  申请人：Boga RameshBabu

  公开号：US20050084977A1

  公开（公告）日：2005-04-21

  The invention provides a breath testing device which visually indicates the presence of ammonia in a patient's breath, in particular ammonia from helicobacter pylori urease infection. The breath testing device comprises a visual indicating agent which changes color in response to ammonia odors, such as 4,4′-bis(dimethylamino)-benzhydrol (Michler's hydrol or BDMB), pararosaniline base and alpha-naphtholbenzein. The indicating agent is applied to a substrate which is then inserted into a tube or straw, which can be attached to the inlet of a breath collection balloon. When the patient blows into the tube or straw, the indicating agent will change color if it detects levels of ammonia which are consistent with helicobacter pylori urease infection.

  本发明提供了一种呼气检测装置，它能直观地显示患者呼气中是否存在氨，特别是来自以下方面的氨 幽门螺旋杆菌 脲酶感染产生的氨。这种呼气测试装置包括一种视觉指示剂，它在氨气味的作用下会变色，例如 4,4′-双（二甲基氨基）-苯甲醇（Michler's hydrol 或 BDMB）、对氨基苯胺碱和α-萘酚本素。指示剂涂抹在基质上，然后将基质插入管子或吸管中，吸管可连接到呼吸收集气球的入口。当患者对着管子或吸管吹气时，如果指示剂检测到符合以下条件的氨水平，指示剂就会变色 幽门螺旋杆菌 尿素酶感染。
• Absorbing organic reagent into diagnostic test devices by formation of amine salt complexes
  申请人：Profitt A. James

  公开号：US20050106748A1

  公开（公告）日：2005-05-19

  A method of applying an organic acid reagent having limited transolubility in organic solvents, aqueous solvents, and mixtures thereof to a component of a diagnostic test device by mixing an organic acid reagent and an amine to form a salt complex, dissolving the salt complex in a solvent to release the organic acid reagent into the solvent, and applying the solvent to the component of the diagnostic test device such that the organic acid reagent present in the solvent becomes integrated into the diagnostic test device. The amine is represented by the formula H m NR n wherein m is 0, 1, or 2; n is 1, 2, or 3; the sum of m and n is 3; and R is an independently selected group which renders the salt complex soluble in aqueous solvents, organic solvents, or mixtures thereof. The amine is also represented by the formula NR 4 + wherein R is an independently selected group which renders the salt complex soluble in aqueous solvents, organic solvents, or mixtures thereof. The organic acid reagent is selected from a carboxylic acid, a sulfonic acid, a phosphoric acid, and mixtures thereof. Preferred reagents are dyes like pyragallol red. In a specific embodiment the diagnostic test device is a paper test strip.

  一种将在有机溶剂、水性溶剂及其混合物中具有有限转溶性的有机酸试剂应用于诊断检测设备部件的方法，其方法是将有机酸试剂和胺混合形成盐络合物，将盐络合物溶解在溶剂中以将有机酸试剂释放到溶剂中，然后将溶剂应用于诊断检测设备部件，使存在于溶剂中的有机酸试剂融入诊断检测设备中。胺用式 H m NR n 其中 m 为 0、1 或 2；n 为 1、2 或 3；m 和 n 之和为 3；R 为独立选择的基团，该基团可使盐复合物溶于水溶剂、有机溶剂或其混合物中。胺也可由式 NR 4 + 其中 R 是一个独立选择的基团，可使盐络合物溶于水溶剂、有机溶剂或其混合物中。有机酸试剂选自羧酸、磺酸、磷酸及其混合物。首选的试剂是吡咯红等染料。在一个具体的实施方案中，诊断检测装置是纸质试纸。
• Personal care products with visual indicator of vaginitis
  申请人：Boga RameshBabu

  公开号：US20050124072A1

  公开（公告）日：2005-06-09

  There is provided a personal care product having a body side liner, a baffle and an indicator strip with two ends. The indicator has an amine sensitive dye near at least one end. The indicator extends from the target area just below the liner to just above the baffle such that the dye deposit is visible to an unaided eye. The dye changes color in the presence of amines which are characteristic of infection, thus alerting the user to the possibility of infection. Such an indicator placed in a feminine hygiene pad, for example, may be useful in the diagnosis of vaginitis.

  提供了一种个人护理产品，它有一个主体侧衬垫、一个挡板和一个两端有指示器的指示条。指示条至少在一端附近具有胺敏感染料。指示条从衬垫下方的目标区域一直延伸到挡板上方，这样染料沉积物就能被肉眼看到。当存在感染所特有的胺类物质时，染料就会变色，从而提醒使用者注意感染的可能性。例如，放置在女性卫生垫中的这种指示器可能有助于诊断阴道炎。