m5Cyt-Ribf.rCyd.hm5Cyt-Ribf

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 嘧啶核苷
• 英文名称: m5Cyt-Ribf.rCyd.hm5Cyt-Ribf
• 英文别名: 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(hydroxymethyl)pyrimidin-2-one;4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidin-2-one;4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
• 化学式: C29H43N9O16
• 分子量: 773.7
• InChiKey: PAZYPTRSBHMKTR-UEFKCPGGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -7.89
• 重原子数：
  54
• 可旋转键数：
  7
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.59
• 拓扑面积：
  406
• 氢给体数：
  13
• 氢受体数：
  16

文献信息

• METHODS AND PRODUCTS FOR EXPRESSING PROTEINS IN CELLS
  申请人：Factor Bioscience Inc.

  公开号：EP2914728A1

  公开（公告）日：2015-09-09
• [EN] METHODS AND PRODUCTS FOR EXPRESSING PROTEINS IN CELLS<br/>[FR] PROCÉDÉS ET PRODUITS POUR L'EXPRESSION DE PROTÉINES DANS DES CELLULES
  申请人：FACTOR BIOSCIENCE INC

  公开号：WO2014071219A1

  公开（公告）日：2014-05-08

  The present invention relates in part to nucleic acids encoding proteins, therapeutics comprising nucleic acids encoding proteins, methods for inducing cells to express proteins using nucleic acids, methods, kits and devices for transfecting, gene editing, and reprogramming cells, and cells, organisms, and therapeutics produced using these methods, kits, and devices. Methods and products for altering the DNA sequence of a cell are described, as are methods and products for inducing cells to express proteins using synthetic RNA molecules. Therapeutics comprising nucleic acids encoding gene-editing proteins are also described.