N-[(9Z,21Z,33E)-27-acetamido-7,19,31-trihydroxy-10,22,34-trimethyl-2,8,14,20,26,32-hexaoxo-15-(2-oxopropyl)-1,13,25-trioxa-7,19,31-triazacyclohexatriaconta-9,21,33-trien-3-yl]acetamide

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 大环内酰胺类
• 英文名称: N-[(9Z,21Z,33E)-27-acetamido-7,19,31-trihydroxy-10,22,34-trimethyl-2,8,14,20,26,32-hexaoxo-15-(2-oxopropyl)-1,13,25-trioxa-7,19,31-triazacyclohexatriaconta-9,21,33-trien-3-yl]acetamide
• 化学式: C₄₀H₆₁N₅O₁₅
• 分子量: 851.9
• InChiKey: DKTIACCDXSJFBS-MAEHEDQVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.7
• 重原子数：
  60
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  276
• 氢给体数：
  5
• 氢受体数：
  15

文献信息

• METHOD FOR DETECTING INFECTIONS
  申请人：Doyle John Martin

  公开号：US20140178902A1

  公开（公告）日：2014-06-26

  The present invention relates to a method for detecting infections caused by or associated with siderophore-secreting microorganisms and kits and components used therein for carrying out the method. In one aspect the invention relates to a method for detecting siderophores and/or detecting infections caused by or associated with siderophore-secreting microorganisms in a biological sample of a subject, the method comprising providing a solid support having either bound siderophore or a conjugate thereof, or bound anti-siderophore antibody; reacting the bound siderophore or a conjugate thereof, with an anti-siderophore antibody, and a biological sample of a subject; or reacting the bound anti-siderophore antibody with a siderophore or conjugate thereof, and a biological sample of a subject; and detecting and/or quantifying the presence of the siderophore in the biological sample.