5-[1-Hydroxy-3-[hydroxy(propoxy)phosphoryl]oxypropan-2-yl]oxypentanoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油磷脂
• 英文名称: 5-[1-Hydroxy-3-[hydroxy(propoxy)phosphoryl]oxypropan-2-yl]oxypentanoic acid
• 英文别名: 5-[1-hydroxy-3-[hydroxy(propoxy)phosphoryl]oxypropan-2-yl]oxypentanoic acid
• 化学式: C₁₁H₂₃O₈P
• 分子量: 314.27
• InChiKey: VBPQGLHDMAXQJQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.7
• 重原子数：
  20
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.91
• 拓扑面积：
  123
• 氢给体数：
  3
• 氢受体数：
  8

文献信息

• Oxidized Lipids and Treatment or Prevention of Fibrosis
  申请人：Vascular Biogenics Ltd.

  公开号：US20170258818A1

  公开（公告）日：2017-09-14

  The present invention is directed to methods of treating or preventing fibrosis comprising an oxidized lipid or pharmaceutical composition comprising the same.
• US8802875B2
  申请人：——

  公开号：US8802875B2

  公开（公告）日：2014-08-12
• [EN] MOTILE SPERM DOMAIN CONTAINING PROTEIN 2 AND INFLAMMATION<br/>[FR] PROTÉINE 2 CONTENANT LE DOMAINE DU SPERME MOTILE ET INFLAMMATION
  申请人：VASCULAR BIOGENICS LTD

  公开号：WO2017021855A2

  公开（公告）日：2017-02-09

  Disclosed herein are methods of treating, preventing, or reducing the incidence of an inflammatory disease or disorder and methods of inhibiting, preventing, or reducing the incidence of one or more activities in a cell with an inhibitor of a Motile Sperm Domain containing Protein 2 (MOSPD2). Also disclosed are inhibitors of MOSPD2 and pharmaceutical compositions containing MOSPD2 inhibitors.