2-Ethyl-3-[6-ethyl-5-[6-ethyl-5-[6-ethyl-5-(6-ethyl-3,4,5-trimethyloxan-2-yl)oxy-3,4-dimethyloxan-2-yl]oxy-3,4-dimethyloxan-2-yl]oxy-3,4-dimethyloxan-2-yl]oxy-6-[2-ethyl-6-(2-ethyl-6-methoxy-4,5-dimethyloxan-3-yl)oxy-4,5-dimethyloxan-3-yl]oxy-4,5-dimethyloxane

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧烷类
• 英文名称: 2-Ethyl-3-[6-ethyl-5-[6-ethyl-5-[6-ethyl-5-(6-ethyl-3,4,5-trimethyloxan-2-yl)oxy-3,4-dimethyloxan-2-yl]oxy-3,4-dimethyloxan-2-yl]oxy-3,4-dimethyloxan-2-yl]oxy-6-[2-ethyl-6-(2-ethyl-6-methoxy-4,5-dimethyloxan-3-yl)oxy-4,5-dimethyloxan-3-yl]oxy-4,5-dimethyloxane
• 英文别名: 2-ethyl-3-[6-ethyl-5-[6-ethyl-5-[6-ethyl-5-(6-ethyl-3,4,5-trimethyloxan-2-yl)oxy-3,4-dimethyloxan-2-yl]oxy-3,4-dimethyloxan-2-yl]oxy-3,4-dimethyloxan-2-yl]oxy-6-[2-ethyl-6-(2-ethyl-6-methoxy-4,5-dimethyloxan-3-yl)oxy-4,5-dimethyloxan-3-yl]oxy-4,5-dimethyloxane
• 化学式: C₆₅H₁₁₈O₁₄
• 分子量: 1123.6
• InChiKey: WMZGOWKFXFCMGG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  16.7
• 重原子数：
  79
• 可旋转键数：
  20
• 环数：
  7.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  129
• 氢给体数：
  0
• 氢受体数：
  14

文献信息

• INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN THE ISOELECTRIC POINT OF WHICH IS COMPRISED IN 5.8 AND 8.5 AND AN ANIONIC COMPOUND BEARING CARBOXYLATE CHARGES AND HYDROPHOBIC RADICALS
  申请人：ADOCIA

  公开号：US20140235536A1

  公开（公告）日：2014-08-21

  A composition in the form of an injectable aqueous solution, the pH of which is from 6.6 to 7.8, comprises at least: a) a basal insulin, the isoelectric point pI of which is between 5.8 and 8.5; and b) an anionic compound bearing carboxylate charges and hydrophobic radicals. The composition may also include a prandial insulin.