Methyl 1-tert-butylazetidine-3-carboxylate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氮杂环丁烷
• 英文名称: Methyl 1-tert-butylazetidine-3-carboxylate
• 英文别名: methyl 1-tert-butylazetidine-3-carboxylate
• 化学式: C₉H₁₇NO₂
• 分子量: 171.24
• InChiKey: VPVQXZCKHVAGTI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.89
• 拓扑面积：
  29.5
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• 1,3-DIARYL-SUBSTITUTED HETEROCYCLIC PESTICIDES
  申请人：E I DU PONT DE NEMOURS AND COMPANY

  公开号：US20150126364A1

  公开（公告）日：2015-05-07

  Disclosed are compounds of Formula 1, N-oxides, and salts thereof, wherein Q is and Z 1 , Z 2 , J 1 , J 2 , M, R 1a , R 1b , R 2a , R 2b , R 2c , R 2d , R 14 and R 14a are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound or a composition of the invention.

  本发明揭示了公式1，N-氧化物及其盐的化合物，其中Q为，Z1，Z2，J1，J2，M，R1a，R1b，R2a，R2b，R2c，R2d，R14和R14a如所述的定义。本发明还揭示了包含公式1化合物的组合物以及用于控制无脊椎动物害虫的方法，包括将该害虫或其环境与本发明化合物或组合物的生物有效量接触。
• RHO-ASSOCIATED PROTEIN KINASE INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD AND USE THEREOF
  申请人：BEIJING TIDE PHARMACEUTICAL CO., LTD.

  公开号：US20190276440A1

  公开（公告）日：2019-09-12

  The present invention relates to a Rho-associated protein kinase inhibitor of formula (I), a pharmaceutical composition comprising the same, a preparation method thereof, and a use of the same in preventing or treating a disease mediated by Rho-associated protein kinase (ROCK).
• US9113631B2
  申请人：——

  公开号：US9113631B2

  公开（公告）日：2015-08-25