[(3R,3aR,6S,6aS)-3,6-dihydroxy-3,3a,5,6a-tetrahydro-2H-furo[3,2-b]furan-6-yl] (Z)-octadec-9-enoate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 呋喃类
• 英文名称: [(3R,3aR,6S,6aS)-3,6-dihydroxy-3,3a,5,6a-tetrahydro-2H-furo[3,2-b]furan-6-yl] (Z)-octadec-9-enoate
• 化学式: C₂₄H₄₂O₆
• 分子量: 426.6
• InChiKey: YIEDZZIRNWRJIW-QUVXAJQXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  30
• 可旋转键数：
  17
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  85.2
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• Composition comprising isosorbide monooleate
  申请人：BASF SE

  公开号：US10052272B2

  公开（公告）日：2018-08-21

  The present invention relates to a composition comprising isosorbide monooleate, a first surfactant selected from the group consisting of an alkyl glycoside having a weight average of the number of C-atoms in the alkyl chain of more than 11, cocoamidopropyl betaine and mixtures thereof, a second surfactant which is an alkyl glycoside having a weight average of the number of C-atoms in the alkyl chain of less than 11 and water. Furthermore it relates to a process for making this composition and to a cosmetic formulation, comprising this composition.

  本发明涉及一种组合物，该组合物包含单油酸异山梨醇酯、第一种表面活性剂（选自烷基链中 C 原子数的重量平均值大于 11 的烷基糖苷、椰油酰胺丙基甜菜碱及其混合物）、第二种表面活性剂（烷基链中 C 原子数的重量平均值小于 11 的烷基糖苷）和水。此外，它还涉及一种制造这种组合物的工艺和一种包含这种组合物的化妆品配方。
• Abuse resistant capsule
  申请人：R.P. Scherer Technologies, LLC

  公开号：US10420729B2

  公开（公告）日：2019-09-24

  The present invention is directed to an immediate release and extended release capsule or capsule fill which mitigates the abuse of abuse-susceptible active pharmaceutical ingredients by direct intravenous injection. The fill comprises a parenteral abuse resistant liquid formulation which when mixed with water and heated, results in a turbid, viscous or bubbling mixture that is not injectable with a standard insulin syringe. The abuse-susceptible active pharmaceutical ingredient is selected from the group consisting of opiates, opioids, tranquilizers, stimulants and narcotics.

  本发明涉及一种速释和缓释胶囊或胶囊填充剂，它可减少通过直接静脉注射滥用易滥用的活性药物成分。填充物包括一种肠外抗滥用液体制剂，当与水混合并加热时，会产生一种浑浊、粘稠或起泡的混合物，不能用标准胰岛素注射器注射。抗滥用活性药物成分选自阿片类、阿片类、镇静剂、兴奋剂和麻醉剂。
• ABUSE RESISTANT CAPSULE
  申请人：R.P. Scherer Technologies, LLC

  公开号：EP2968129A1

  公开（公告）日：2016-01-20
• A USE OF ISOSORBIDE MONOOLEATE
  申请人：BASF SE

  公开号：EP3169305A1

  公开（公告）日：2017-05-24
• A COMPOSITION COMPRISING ISOSORBIDE MONOOLEATE
  申请人：BASF SE

  公开号：EP3166585A1

  公开（公告）日：2017-05-17