2-(3-anilinopropyl)-7H-purin-6-amine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 咪唑并嘧啶类
• 英文名称: 2-(3-anilinopropyl)-7H-purin-6-amine
• 化学式: C₁₄H₁₆N₆
• 分子量: 268.32
• InChiKey: LQWWMWXKPUBSDT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  20
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  92.5
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• ANTISENSE OLIGONUCLEOTIDES FOR TREATMENT OF CANCER STEM CELLS
  申请人：ANDES BIOTECHNOLOGIES S.A.

  公开号：EP2970970A1

  公开（公告）日：2016-01-20
• [EN] ANTISENSE OLIGONUCLETOTIDES FOR TREATMENT OF CANCER STEM CELLS<br/>[FR] OLIGONUCLÉOTIDES ANTISENS POUR LE TRAITEMENT DE CELLULES SOUCHES CANCÉREUSES
  申请人：ANDES BIOTECHNOLOGIES S A

  公开号：WO2014153209A1

  公开（公告）日：2014-09-25

  The invention provides oligonucleotides complementary to a non-coding chimeric mitochondrial RNA as well as compositions and kits comprising the same, and their use in treating and preventing metastasis or relapse of a cancer in an individual previously treated for cancer with a therapy. The invention also provides oligonucleotides complementary to a non-coding chimeric mitochondrial RNA as well as compositions and kits comprising the same, and their use in treating a refractory cancer (e.g., a refractory HPV-associated cancer).