cis-2,4,5-tris(2-nitrophenyl)-2-imidazoline

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: cis-2,4,5-tris(2-nitrophenyl)-2-imidazoline
• 英文别名: 2,4,5-tris(2-nitrophenyl)-4,5-dihydro-1H-imidazole；(4R,5S)-2,4,5-tris(2-nitrophenyl)-4,5-dihydro-1H-imidazole
• 化学式: C₂₁H₁₅N₅O₆
• 分子量: 433.38
• InChiKey: NAAUIZGGOJFOGE-BGYRXZFFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  32
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  162
• 氢给体数：
  1
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  邻硝基苯甲醛 在 氨 作用下， 以 四氢呋喃 为溶剂， 以50%的产率得到cis-2,4,5-tris(2-nitrophenyl)-2-imidazoline
  参考文献：
  名称：

  摘要：

  Novel data were obtained concerning the reaction of aromatic aldehydes with ammonia. A preparative method for the synthesis of new substituted 1,3,5-triaryl-2,4-diazapenta-1,4-dienes was developed. These products are the starting reactants for syntheses of cis- and trans-2,4,5-triaryl-2-imidazolines and 2,4,5-triarylimidazoles.

  DOI：

  10.1023/a:1023915024572

文献信息

• ——
  作者：M. V. Proskurnina、N. A. Lozinskaya、S. E. Tkachenko、N. S. Zefirov

  DOI：10.1023/a:1020997325550

  日期：——

  By reaction of aromatic aldehydes with ammonium acetate a series of 1,2-diaryl-1,2-diamino-ethanes and their derivatives was obtained. The mechanism of reaction was suggested and its principal stages were proved. Reactions with ammonium acetate of aromatic aldehydes containing ortho-substituents resulted in the corresponding 2,4,5-triaryl-4,5-dihydroimidazoles.
• ——
  作者：N. A. Lozinskaya

  DOI：10.1023/a:1023915024572

  日期：——

  Novel data were obtained concerning the reaction of aromatic aldehydes with ammonia. A preparative method for the synthesis of new substituted 1,3,5-triaryl-2,4-diazapenta-1,4-dienes was developed. These products are the starting reactants for syntheses of cis- and trans-2,4,5-triaryl-2-imidazolines and 2,4,5-triarylimidazoles.