N-芴甲氧羰基-一聚乙二醇-琥珀酰亚胺酯 | 1807521-05-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 芴
• 中文名称: N-芴甲氧羰基-一聚乙二醇-琥珀酰亚胺酯
• 英文名称: Fmoc-PEG1-NHS ester
• 英文别名: (2,5-dioxopyrrolidin-1-yl) 3-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]propanoate
• CAS: 1807521-05-6
• 化学式: C₂₄H₂₄N₂O₇
• 分子量: 452.5
• InChiKey: BGPXUJXGIVJFGP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  33
• 可旋转键数：
  11
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  111
• 氢给体数：
  1
• 氢受体数：
  7

文献信息

• Comb Polymers
  申请人：Norman Timothy John

  公开号：US20080220005A1

  公开（公告）日：2008-09-11

  The present invention provides a process for producing a comb polymer comprising the steps of: a) providing: (i) (w+z) molar equivalents of a monomer; (ii) one molar equivalent of an initiator compound of formula (IX), wherein B 3 represents a halogen, B 2 represents H or a halogen, Y 1 represents a group capable of attaching the residue of an antibody or fragment thereof or capable of being converted into such a group, L represents a linker group, y is 1, 2 or 3, w is at least 1 and z is 0 or greater; (iii) a catalyst capable of catalysing the polymerisation of a plurality of the monomers to produce the comb polymer; and b) causing the catalyst to catalyse, in combination with the initiator, the polymerisation of a plurality of the monomers (i) to produce the comb polymer.
• FINE PARTICLES CONTAINING RARE EARTH ELEMENT AND FLUORESCENT PROBE USING THE SAME
  申请人：MATSUURA Daisuke

  公开号：US20080292520A1

  公开（公告）日：2008-11-27

  A main object of the present invention is to provide: fine particles whose excitation light is not the one such as UV light or the like which has negative effects on a subject to be analyzed, emit light stably, and has excellent light emitting efficiency, and a fluorescent probe labeled with the fine particles. In order to achieve the aforementioned object, the present invention provides a fluorescent probe comprising: fine particles containing a rare earth element characterized in that they are excited by light having a wavelength in a range of 500 nm to 2000 nm and thereby emit up-conversion emission; and a specific binding substance which binds to the fine particles containing a rare earth element.
• HETEROARYLENE-BRIDGED BENZODIAZEPINE DIMERS, CONJUGATES THEREOF, AND METHODS OF MAKING AND USING
  申请人：Bristol-Myers Squibb Company

  公开号：US20160199510A1

  公开（公告）日：2016-07-14

  Benzodiazepine dimers having a structure represented by wherein X comprises a heteroaromatic moiety and is as further defined in the application; R 1 is and the other variables in formulae (I), (Ia), and (Ib) are as defined in the application. Such dimers are useful as anti-cancer agents, especially when used in an antibody-drug conjugate (ADC).
• BENZODIAZEPINE DIMERS, CONJUGATES THEREOF, AND METHODS OF MAKING AND USING
  申请人：Bristol-Myers Squibb Company

  公开号：US20160200742A1

  公开（公告）日：2016-07-14

  Benzodiazepine dimers having a structure represented by wherein R 1 is wherein the variables in formulae (I), (Ia), and (Ib) are as defined in the application. Such dimers are useful as anti-cancer agents, especially when used in an antibody-drug conjugate (ADC).
• US7560284B2
  申请人：——

  公开号：US7560284B2

  公开（公告）日：2009-07-14