6,6-dimethyl-3,3a,5,6a-tetrahydro-2H-furo[3,2-b]furan

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 呋喃类
• 英文名称: 6,6-dimethyl-3,3a,5,6a-tetrahydro-2H-furo[3,2-b]furan
• 化学式: C₈H₁₄O₂
• 分子量: 142.2
• InChiKey: RBFUGCIJGBJYMR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• SUBSTITUTED 4-ALKOXYPICOLINAMIDE ANALOGS AS MGLUR5 NEGATIVE ALLOSTERIC MODULATORS AND METHODS OF MAKING AND USING THE SAME
  申请人：VANDERBILT UNIVERSITY

  公开号：US20170247366A1

  公开（公告）日：2017-08-31

  Disclosed are negative allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with glutamate dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
• [EN] NOVEL METHODS OF USING NITRIC OXIDE DONOR COMPOUNDS FOR TREATMENT OF COVID-19 AND OTHER INFECTIOUS DISEASES<br/>[FR] NOUVEAUX PROCÉDÉS D'UTILISATION DE COMPOSÉS DONNEURS D'OXYDE NITRIQUE POUR LE TRAITEMENT DE LA COVID-19 ET D'AUTRES MALADIES INFECTIEUSES
  申请人：COEURATIVE INC

  公开号：WO2021202317A2

  公开（公告）日：2021-10-07

  The present invention provides novel methods of using nitric oxide donor compounds for treating infectious diseases, for example, COVID-19.