1-naphthylmethyl allyl sulfide | 132974-65-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 1-naphthylmethyl allyl sulfide
• 英文别名: 1-Allylmercaptomethyl-naphthalin；1-(Prop-2-enylsulfanylmethyl)naphthalene
• CAS: 132974-65-3
• 化学式: C₁₄H₁₄S
• 分子量: 214.331
• InChiKey: MRVZKVXZPIOCKZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  25.3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1-naphthylmethyl allyl sulfide 、 dichlorocarbene 生成 (氯甲基)萘
  参考文献：
  名称：

  AL-SHURA, A. M.;BRATKOV, A. A.;ANISIMOV, A. V.;VIKTOROVA, E. A., BECTH. MGU. CEP. 2, 31,(1990) N, S. 392-397

  摘要：

  DOI：
• 作为产物：
  描述：

  1-mercaptomethylnaphthalene 在 四(三苯基膦)钯 N,N-二异丙基乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 1.0h， 生成 1-naphthylmethyl allyl sulfide
  参考文献：
  名称：

  Allylic protection of thiols and cysteine: II: The N-[2,3,5,6-tetrafluoro-4-(N′-piperidino)-phenyl], N-allyloxycarbonylaminomethyl (Fnam) group

  摘要：

  S-[N-[2,3,5,6-tetrafluoro-4-(N'-piperidino)-phenyl], N-allyloxycarbonyl]-aminomethyl (Fnam) derivatives of thiols in general and cysteine in particular are readily deprotected by palladium catalysed allylic cleavage in the presence of various nucleophilic species. They are perfectly stable in both the basic conditions (piperidine/DMF) of Fmoc group removal and the acidic conditions (TFA/CH2Cl2) of t-Bu and Boc group removal. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(99)00323-3

文献信息

• Sulfonium compound and polymerisation initator comprising the sulfonium compound as the main ingredient
  申请人：SANSHIN KAGAKU KOGYO CO., LTD.

  公开号：EP0393893B1

  公开（公告）日：1995-01-11
• AL-SHURA, A. M.;BRATKOV, A. A.;ANISIMOV, A. V.;VIKTOROVA, E. A., BECTH. MGU. CEP. 2, 31,(1990) N, S. 392-397
  作者：AL-SHURA, A. M.、BRATKOV, A. A.、ANISIMOV, A. V.、VIKTOROVA, E. A.

  DOI：——

  日期：——
• Allylic protection of thiols and cysteine: II: The N-[2,3,5,6-tetrafluoro-4-(N′-piperidino)-phenyl], N-allyloxycarbonylaminomethyl (Fnam) group
  作者：Paloma Gomez-Martinez、André Malanda Kimbonguila、François Guibé

  DOI：10.1016/s0040-4020(99)00323-3

  日期：1999.5

  S-[N-[2,3,5,6-tetrafluoro-4-(N'-piperidino)-phenyl], N-allyloxycarbonyl]-aminomethyl (Fnam) derivatives of thiols in general and cysteine in particular are readily deprotected by palladium catalysed allylic cleavage in the presence of various nucleophilic species. They are perfectly stable in both the basic conditions (piperidine/DMF) of Fmoc group removal and the acidic conditions (TFA/CH2Cl2) of t-Bu and Boc group removal. (C) 1999 Elsevier Science Ltd. All rights reserved.