1,4-dihydro-9,10-dihydroxy-1,4-methanoanthracene | 52457-24-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 1,4-dihydro-9,10-dihydroxy-1,4-methanoanthracene
• 英文别名: (1R,12S)-tetracyclo[10.2.1.02,11.04,9]pentadeca-2,4,6,8,10,13-hexaene-3,10-diol
• CAS: 52457-24-6
• 化学式: C₁₅H₁₂O₂
• 分子量: 224.259
• InChiKey: OIVUMSUWJNHLQC-DTORHVGOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  17
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1,4,4a,9a-Tetrahydro-1,4-endomethylen-anthrachinon 在 sodium hydride 、 氯化铵 作用下， 以 四氢呋喃 为溶剂， 生成 1,4-dihydro-9,10-dihydroxy-1,4-methanoanthracene
  参考文献：
  名称：

  Electronic control of stereoselectivity. 6. Directionality of singlet oxygen addition to 1,4-dimethoxynaphthalenes laterally fused to bridged bicyclic systems

  摘要：

  DOI：

  10.1021/jo01312a019

文献信息

• Synergistic Anticoagulant Composition
  申请人：Lewis David E.

  公开号：US20110082194A1

  公开（公告）日：2011-04-07

  A composition is provided that, when utilized in combination with warfarin, greatly improves the anticoagulant effects of warfarin in mammalian subjects. The composition is a compound having a naphthohydroquinone ring system substantially similar to the ring system of the reduced form of vitamin K 1 and has the general formula: where R 1 and R 4 are hydrogen or acyl, R 2 is a saturated or unsaturated alkyl group with up to 6 carbons, and R 3 is a saturated or unsaturated alkyl group with up to 20 carbons, or R 2 and R 3 are part of a cyclic or polycyclic ring system.
• US8765982B2
  申请人：——

  公开号：US8765982B2

  公开（公告）日：2014-07-01