3-(4-anisidino)-4-cyanobenzo[b][1,6]naphthyridine | 645337-26-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: 3-(4-anisidino)-4-cyanobenzo[b][1,6]naphthyridine
• 英文别名: 3-(4-Methoxyanilino)benzo[b][1,6]naphthyridine-4-carbonitrile；3-(4-methoxyanilino)benzo[b][1,6]naphthyridine-4-carbonitrile
• CAS: 645337-26-4
• 化学式: C₂₀H₁₄N₄O
• 分子量: 326.357
• InChiKey: RURSNRWZHDYLJN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  25
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  70.8
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  3-chloro-4-cyanobenzo<1,6>naphthyridine 、 甲氧苯胺 以 甲醇 为溶剂， 反应 30.0h， 以98%的产率得到3-(4-anisidino)-4-cyanobenzo[b][1,6]naphthyridine
  参考文献：
  名称：

  摘要：

  The elect roreduction of benzo[b][1,6]naphthyridine derivatives in anhydrous media by the polarographic method was studied. It is found that the first step of the process is the transfer of an electron to position 10 of the molecule, which is consistent with the addition of nucleophilic reagents to this particular position of the tricyclic system in question.

  DOI：

  10.1023/a:1024917609689

文献信息

• ——
  作者：E. Yu. Khmel'nitskaya、A. S. Ivanov、N. Z. Tugusheva、N. B. Grigor'ev、V. G. Granik

  DOI：10.1023/a:1024917609689

  日期：——

  The elect roreduction of benzo[b][1,6]naphthyridine derivatives in anhydrous media by the polarographic method was studied. It is found that the first step of the process is the transfer of an electron to position 10 of the molecule, which is consistent with the addition of nucleophilic reagents to this particular position of the tricyclic system in question.