hydron;N,N,2-trimethyl-3-phenothiazin-10-ylpropan-1-amine;chloride

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻嗪类
• 英文名称: hydron;N,N,2-trimethyl-3-phenothiazin-10-ylpropan-1-amine;chloride
• 化学式: C18H23ClN2S
• 分子量: 334.9
• InChiKey: QUVSTPKPFAPBQU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.91
• 重原子数：
  22
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  31.8
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Percutaneously absorbable patches
  申请人：——

  公开号：US20040146548A1

  公开（公告）日：2004-07-29

  It is intended to provide percutaneously absorbable patches having an improved percutaneous absorbability of an anti-inflammatory agent in the form of a salt and an improved stability. Namely, percutaneously absorbable patches having an adhesive base layer which contains an anti-inflammatory agent in the form of a salt, an ammonium salt compound, an absorption enhancer and/or a solubilizer.

  本发明旨在提供可经皮吸收的贴片，其盐形式消炎剂的经皮吸收性得到改善，稳定性得到提高。也就是说，经皮可吸收贴片具有粘合剂基层，该基层含有盐、铵盐化合物、吸收促进剂和/或增溶剂形式的消炎剂。
• PERCUTANEOUSLY ABSORBABLE PATCHES
  申请人：Hisamitsu Pharmaceutical Co., Inc.

  公开号：EP1400240B1

  公开（公告）日：2010-04-21
• Anti-scarring drug combinations and use thereof
  申请人：Hunter L. William

  公开号：US20070208134A1

  公开（公告）日：2007-09-06

  The present invention provides devices or implants that comprise anti-scarring drug combinations, methods or making such devices or implants, and methods of inhibiting fibrosis between the devices or implants and tissue surrounding the devices or implants. The present invention also provides compositions that comprise anti-fibrotic drug combinations, and their uses in various medical applications including the prevention of surgical adhesions, treatment of inflammatory arthritis, treatment of scars and keloids, the treatment of vascular disease, and the prevention of cartilage loss.