cis/trans-3-Amino-2-methyl-pent-2-en-nitril | 53094-19-2

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: cis/trans-3-Amino-2-methyl-pent-2-en-nitril
• 英文别名: (Z)-3-amino-2-methylpent-2-enenitrile
• CAS: 53094-19-2
• 化学式: C₆H₁₀N₂
• 分子量: 110.159
• InChiKey: VPFGWBGYONWGNJ-WAYWQWQTSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  8
• 可旋转键数：
  1
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  49.8
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  丙腈 生成 cis/trans-3-Amino-2-methyl-pent-2-en-nitril
  参考文献：
  名称：

  乙腈一钠，它们的制备，性质和反应

  摘要：

  通过双（三甲基甲硅烷基）酰胺钠与乙腈或相应的腈在任何一种溶液中在低温下反应，制得乙腈单钠盐和同源化合物。讨论了这些化合物的IR和NMR光谱。乙腈钠仅加到极性双键（羰基和氰基）上。已表明乙腈和类似化合物是腈与烯胺的缩合反应的中间体。乙腈钠最好是在氰化物受体存在下充当卡宾生成器。

  DOI：

  10.1016/s0022-328x(00)92412-4

文献信息

• Monosodium acetonitriles, their preparation, properties and reactions
  作者：Carl Krüger

  DOI：10.1016/s0022-328x(00)92412-4

  日期：1967.7

  Monosodium acetonitrile and homologous compounds are prepared by the reaction of sodium bis(trimethylsilyl)amide with acetonitrile or the corresponding nitriles in either solution at low temperature. The IR and NMR spectra of these compounds are discussed. Sodium acetonitrile adds to polar double bonds (carbonyl and cyano groups) only. It is shown that sodium acetonitrile and analogous compounds are

  通过双（三甲基甲硅烷基）酰胺钠与乙腈或相应的腈在任何一种溶液中在低温下反应，制得乙腈单钠盐和同源化合物。讨论了这些化合物的IR和NMR光谱。乙腈钠仅加到极性双键（羰基和氰基）上。已表明乙腈和类似化合物是腈与烯胺的缩合反应的中间体。乙腈钠最好是在氰化物受体存在下充当卡宾生成器。
• Benzamidines, alkamidines and formamidines formed by use of aryl- and alkyliminodimagnesium: Molar ratio and structure of reagent governing the reaction
  作者：Masao Okubo、Yasumasa Omote

  DOI：10.1002/(sici)1099-1395(199604)9:4<212::aid-poc775>3.0.co;2-a

  日期：1996.4

  In order to extend the the method for preparation of amidines using N-Mg reagents, aryl- and alkyliminodimagnesium [IDMg, ArN(MgBr)(2) and RN(MgBr)(2)] were reacted with esters, amides, ortho- esters, acetals, aminoacetal and arene- and alkane carbonitriles, Among the compounds used, aminoacetal and carbonitriles were proved to be useful as starting materials for amidine preparation; alkyl-IDMgs were successfully used for the first time, It was noted that an excess molar amount of IDMg is needed in the reported reaction of ArN(MgBr), with benzonitrile (aryl-aryl combination), whereas no excess is needed in aryl-alkyl, alkyl-aryl, and alkyl-alkyl combinations of reagent and substrate, From the viewpoint previously proposed in terms of relative efficiency of single electron transfer in the reactions of magnesium reagents, the most probable reason for the difference in the need for an excess molar amount of aryl and alkyl IDMg was ascribed to the difference in the electron-donating abilities of reagents, Additional minor reasons are discussed.