2,4,6-octatriynenitrile | 98436-69-2

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 2,4,6-octatriynenitrile
• 英文别名: octa-2,4,6-triynenitrile；Octa-2,4,6-triinnitril
• CAS: 98436-69-2
• 化学式: C₈H₃N
• 分子量: 113.119
• InChiKey: DHPXVNMVXDJNGW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  9
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  23.8
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  戊-1,3-二炔 在 甲醇 、 ammonium chloride 、 氨 、 phosphorus pentoxide 、 copper(l) chloride 作用下， 100.0 ℃ 、1.33 Pa 条件下， 生成 2,4,6-octatriynenitrile
  参考文献：
  名称：

  Bohlmann; Mannhardt, Chemische Berichte, 1956, vol. 89, p. 2268,2272

  摘要：

  DOI：

文献信息

• OXINDOLE DERIVATIVES
  申请人：Chen Li

  公开号：US20080081810A1

  公开（公告）日：2008-04-03

  There is provided compounds of the formula wherein R 6 , V, W, X, Y, Q and n are as described. The compounds exhibit activity as anticancer agents.

  提供的化合物具有以下结构式，其中R6、V、W、X、Y、Q和n如所述。这些化合物表现出抗癌药物的活性。
• DIARYLTHIOHYDANTOIN COMPOUNDS
  申请人：Jung Michael

  公开号：US20080139634A2

  公开（公告）日：2008-06-12

  The present invention relates to diarylthiohydantoin compounds and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.

  本发明涉及二芳基硫代异噁唑酮化合物及其合成方法，以及将其用于治疗激素难治性前列腺癌的方法。
• USE OF ANTIMICROBIAL POLYMERS FOR RE-SENSITIZATION OF MICROORGANISMS UPON EMERGENCE OF RESISTANCE TO ANTI-MICROBIAL AGENTS
  申请人：Mor Amram

  公开号：US20110105386A1

  公开（公告）日：2011-05-05

  Methods and compositions for treating microbial infections associated with an emergence of resistance of a pathogenic microorganism to an antimicrobial agent, following treatment with antimicrobial agent are disclosed. The methods are effected by using a polymer which exhibits antimicrobial re-sensitizing activity, for re-sensitizing the pathogenic microorganisms to the antimicrobial agent, in combination with the antimicrobial agent. Further disclosed are novel polymers having an antimicrobial re-sensitizing activity.
• ANTIBIOTIC DRUG DELIVERY AND POTENTIATION
  申请人：Mor Amram

  公开号：US20120237562A1

  公开（公告）日：2012-09-20

  Disclosed are compositions-of-matter comprising polymer-mediated cochleates, which are formed from a calcium-free mixture of a wide variety of phospholipids that are atypical for forming cochleates. Further disclosed are compositions-of-matter comprising these cochleates which co-encapsulate another bioactive agent. The polymer mediating the formation of these cochleates exhibits a plurality of positively charged amino acid residues and omega-amino-fatty acid moieties, and may further exhibit antimicrobial, anticancerous and drug-potentiating activity. Further disclosed are pharmaceutical compositions and methods using the compositions-of-matter disclosed herein, and processes of preparing same.
• US8058269B2
  申请人：——

  公开号：US8058269B2

  公开（公告）日：2011-11-15