3-Methylenetetrahydro-2H-thiopyran | 792959-19-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 噻烷
• 英文名称: 3-Methylenetetrahydro-2H-thiopyran
• 英文别名: 3-methylidenethiane
• CAS: 792959-19-4
• 化学式: C₆H₁₀S
• 分子量: 114.21
• InChiKey: ORXNDJXLIIJEEW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  7
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  25.3
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• [EN] NOVEL COMPOUNDS<br/>[FR] NOUVEAUX COMPOSÉS
  申请人：GLAXOSMITHKLINE IP DEV LTD

  公开号：WO2015180612A1

  公开（公告）日：2015-12-03

  Disclosed are novel retinoid-related orphan receptor gamma (RORγ) modulators and their use in the treatment of diseases mediated by RORγ.

  揭示了新型视黄醇相关孤儿受体γ（RORγ）调节剂及其在通过RORγ介导的疾病治疗中的应用。
• PEPTIDES AND COMPOUNDS THAT BIND TO A RECEPTOR
  申请人：Dower J. William

  公开号：US20070148091A1

  公开（公告）日：2007-06-28

  Described are peptides and peptide mimetics that bind to and activate the thrombopoietin receptor. Such peptides and peptide mimetics are useful in methods for treating hematological disorders and particularly, thrombocytopenia resulting from chemotherapy, radiation therapy, or bone marrow transfusions as well as in diagnostic methods employing labeled peptides and peptide mimetics.
• COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS
  申请人：Tong Ling

  公开号：US20120015926A1

  公开（公告）日：2012-01-19

  This invention relates to compounds of the Formula (I): (Chemical formula should be inserted here as it appears on abstract in paper form) (I) or a pharmaceutically acceptable salt thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF- or combinations thereof.
• NOVEL COMPOUNDS
  申请人：GlaxoSmithKline Intellectual Property Developement Limited

  公开号：US20170197978A1

  公开（公告）日：2017-07-13

  The present invention relates to novel retinoid-related orphan receptor gamma (RORγ) modulators and their use in the treatment of diseases mediated by RORγ.
• US8227422B2
  申请人：——

  公开号：US8227422B2

  公开（公告）日：2012-07-24