(2S,3S)-1,4-bis(2-naphthylmethoxy)-2,3-diazidobutane | 254101-54-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: (2S,3S)-1,4-bis(2-naphthylmethoxy)-2,3-diazidobutane
• 英文别名: 2-[[(2S,3S)-2,3-diazido-4-(naphthalen-2-ylmethoxy)butoxy]methyl]naphthalene
• CAS: 254101-54-7
• 化学式: C₂₆H₂₄N₆O₂
• 分子量: 452.516
• InChiKey: OFCCYKRXFQMHAR-CLJLJLNGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.3
• 重原子数：
  34
• 可旋转键数：
  11
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  47.2
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  (2S,3S)-1,4-bis(2-naphthylmethoxy)-2,3-diazidobutane 在 palladium on activated charcoal 氢气 作用下， 以 甲醇 为溶剂， 20.0 ℃ 、101.32 kPa 条件下， 反应 18.0h， 以100%的产率得到(2S,3S)-1,4-bis<(2-naphthyl)methoxy>-2,3-diaminobutane
  参考文献：
  名称：

  Syntheses of C2-symmetric vicinal diamines derived from tartaric acid

  摘要：

  C-2-symmetric vicinal diamines 3b-f, derived from L-tartaric acid, with increasingly bulky terminal ether functionalities were prepared using two distinct sequences. Diamines 3b,c were obtained from the corresponding vicinal diols 4b,c, while diamines 3d-f were generated from dihydroxydiazide 7 via deprotection-reprotection strategies. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0957-4166(99)00353-5
• 作为产物：
  描述：

  (2S,3S)-1,4-bis(2-naphthylmethoxy)butane-2,3-diol 在 sodium azide 、 三乙胺 作用下， 以 二氯甲烷 、 二甲基亚砜 为溶剂， 反应 25.0h， 生成 (2S,3S)-1,4-bis(2-naphthylmethoxy)-2,3-diazidobutane
  参考文献：
  名称：

  Syntheses of C2-symmetric vicinal diamines derived from tartaric acid

  摘要：

  C-2-symmetric vicinal diamines 3b-f, derived from L-tartaric acid, with increasingly bulky terminal ether functionalities were prepared using two distinct sequences. Diamines 3b,c were obtained from the corresponding vicinal diols 4b,c, while diamines 3d-f were generated from dihydroxydiazide 7 via deprotection-reprotection strategies. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0957-4166(99)00353-5

文献信息

• Syntheses of C2-symmetric vicinal diamines derived from tartaric acid
  作者：Andreas Scheurer、Paul Mosset、Rolf W. Saalfrank

  DOI：10.1016/s0957-4166(99)00353-5

  日期：1999.9

  C-2-symmetric vicinal diamines 3b-f, derived from L-tartaric acid, with increasingly bulky terminal ether functionalities were prepared using two distinct sequences. Diamines 3b,c were obtained from the corresponding vicinal diols 4b,c, while diamines 3d-f were generated from dihydroxydiazide 7 via deprotection-reprotection strategies. (C) 1999 Elsevier Science Ltd. All rights reserved.