[4,5-二甲氧基-2-(4-甲氧基-苯乙烯基)-苯乙基]-二甲基-胺 | 24993-24-6

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 中文名称: [4,5-二甲氧基-2-(4-甲氧基-苯乙烯基)-苯乙基]-二甲基-胺
• 英文名称: [4,5-dimethoxy-2-(4-methoxy-styryl)-phenethyl]-dimethyl-amine
• 英文别名: [4,5-Dimethoxy-2-(4-methoxy-styryl)-phenaethyl]-dimethyl-amin；4.5.4'-Trimethoxy-2-(2-dimethylamino-aethyl)-stilben；4.5.4'-Trimethoxy-2-(β-dimethylamino-aethyl)-stilben；Tetramethylcoclaurimethin；Dimethyl-<4,5-dimethoxy-2-(4-methoxy-styryl)-phenaethyl>-amin；des-Base v. =,O-Dimethyl-coclaurin；2-[4,5-dimethoxy-2-[2-(4-methoxyphenyl)ethenyl]phenyl]-N,N-dimethylethanamine
• CAS: 24993-24-6
• 化学式: C₂₁H₂₇NO₃
• 分子量: 341.45
• InChiKey: CDEUAIWZABREND-UHFFFAOYSA-N

物化性质

• 熔点：
  85-86 °C
• 沸点：
  481.7±45.0 °C(Predicted)
• 密度：
  1.074±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  25
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  30.9
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  [4,5-二甲氧基-2-(4-甲氧基-苯乙烯基)-苯乙基]-二甲基-胺 在 potassium permanganate 、 丙酮 作用下， 生成 4,5-dimethoxy-2-vinylbenzoic acid
  参考文献：
  名称：

  Survey of Staphylococcal Enterotoxin Genes, Exfoliative Toxin Genes, and Toxic Shock Syndrome Toxin 1 Gene in Non-Staphylococcus aureus Species

  摘要：

  The aim of this study was to analyze the presence of staphylococcal exotoxin genes in staphylococci other than Staphylococcus aureus. Whereas for Staphylococcus aureus a large spectrum of different exotoxins responsible for toxin-mediated diseases has been described, only few and conflicting data are available regarding toxin production in all other staphylococcal species. A collection of clinical non-Staphylococcus aureus staphylococcal isolates were systematically screened for the presence of genes for toxic shock syndrome toxin 1, exfoliative toxins, and classical enterotoxins by using multiplex polymerase chain reaction enzyme immunoassays. In a total of 461 isolates of 18 different (sub)species derived from clinical specimens, no toxin gene sequences were amplified. The results indicate that the occurrence of toxin genes involved in staphylococcal toxin-mediated diseases is at least very rare in human-derived isolates of non-Staphylococcus aureus species.

  DOI：

  10.1007/pl00011281
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 sodium hydroxide 作用下， 生成 [4,5-二甲氧基-2-(4-甲氧基-苯乙烯基)-苯乙基]-二甲基-胺
  参考文献：
  名称：

  Fujita; Tomimatsu, Yakugaku Zasshi/Journal of the Pharmaceutical Society of Japan, 1959, vol. 79, p. 1260,1266

  摘要：

  DOI：

文献信息

• Kondo; Kondo, Journal fur praktische Chemie (Leipzig 1954), 1930, vol. <2>126, p. 46
  作者：Kondo、Kondo

  DOI：——

  日期：——
• Kondo; Kondo, Yakugaku Zasshi/Journal of the Pharmaceutical Society of Japan, 1926, p. 105
  作者：Kondo、Kondo

  DOI：——

  日期：——
• Über die Spaltung des Berbamins mit Chlorkohlensäureester
  作者：Friedrich V. Bruchhausen、Christoph Schäfer

  DOI：10.1002/ardp.19572900803

  日期：——
• THE SYNTHESIS OF dl-ARMEPAVINE¹
  作者：LÉO MARION、LIONEL LEMAY、VINCENT PORTELANCE

  DOI：10.1021/jo01147a033

  日期：1950.1
• Die Konstitution des Phaeantharins
  作者：Friedrich V. Bruchhausen、Alfredo C. Santos、Joachim Knabe、Gertrudes A. Santos

  DOI：10.1002/ardp.19572900507

  日期：——