(3alpha)-Pregnane-3,20-diol | 883879-68-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: (3alpha)-Pregnane-3,20-diol
• 英文别名: (3R,8R,9S,10S,13S,14S,17S)-17-(1-hydroxyethyl)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
• CAS: 883879-68-3
• 化学式: C₂₁H₃₆O₂
• 分子量: 320.5
• InChiKey: YWYQTGBBEZQBGO-KHOKLYTISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  23
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• BRAIN-ENHANCED DELIVERY OF NEUROACTIVE PEPTIDES BY SEQUENTIAL METABOLISM
  申请人：UNIVERSITY OF FLORIDA

  公开号：EP0661986A1

  公开（公告）日：1995-07-12
• EP0661986A4
  申请人：——

  公开号：EP0661986A4

  公开（公告）日：1997-04-23
• Compounds and method for the prevention and treatment of diabetic retinopathy
  申请人：——

  公开号：US20030211981A1

  公开（公告）日：2003-11-13

  The invention provides peptide derivatives designed to deliver peptides having growth factor inhibitory activity, especially somatostatin analogs, to the retina by sequential metabolism. The peptide derivatives, which comprise a dihydropyridine pyridinium salt-type redox targetor moiety, a bulky lipophilic function and an amino acid/dipeptide/tripeptide spacer, are used in the prevention and treatment of diabetic retinopathy.
• US5084277A
  申请人：——

  公开号：US5084277A

  公开（公告）日：1992-01-28
• US5116619A
  申请人：——

  公开号：US5116619A

  公开（公告）日：1992-05-26